{"id":"https://openalex.org/W1978660000","doi":"https://doi.org/10.1083/jcb.3.2.269","title":"STUDIES ON THE ENDOPLASMIC RETICULUM","display_name":"STUDIES ON THE ENDOPLASMIC RETICULUM","publication_year":1957,"publication_date":"1957-03-25","ids":{"openalex":"https://openalex.org/W1978660000","doi":"https://doi.org/10.1083/jcb.3.2.269","mag":"1978660000","pmid":"https://pubmed.ncbi.nlm.nih.gov/13438910","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2224093"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.3.2.269","doi":"https://doi.org/10.1083/jcb.3.2.269","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.3.2.269","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2224093/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113540546","display_name":"Keith R. Porter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keith R. Porter","raw_affiliation_strings":["From The Rockefeller Institute for Medical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From The Rockefeller Institute for Medical Research","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113604582","display_name":"George E. Palade","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George E. Palade","raw_affiliation_strings":["From The Rockefeller Institute for Medical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From The Rockefeller Institute for Medical Research","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":21.0772,"has_fulltext":true,"cited_by_count":775,"citation_normalized_percentile":{"value":0.99942474,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"3","issue":"2","first_page":"269","last_page":"300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.4221000075340271,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.4221000075340271,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.21809999644756317,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.093299999833107,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sarcoplasmic-reticulum","display_name":"sarcoplasmic reticulum","score":0.9769999980926514},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.9390000104904175},{"id":"https://openalex.org/keywords/striated-muscle","display_name":"striated muscle","score":0.9670000076293945},{"id":"https://openalex.org/keywords/myofibrils","display_name":"myofibrils","score":0.8349999785423279},{"id":"https://openalex.org/keywords/sarcomere","display_name":"sarcomere","score":0.8920000195503235},{"id":"https://openalex.org/keywords/muscle-contraction","display_name":"muscle contraction","score":0.6169999837875366},{"id":"https://openalex.org/keywords/sartorius-muscle","display_name":"sartorius muscle","score":0.9279999732971191},{"id":"https://openalex.org/keywords/myocardium","display_name":"myocardium","score":0.9089999794960022},{"id":"https://openalex.org/keywords/excitation-contraction-coupling","display_name":"excitation-contraction coupling","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.8936479687690735},{"id":"https://openalex.org/C7301908","wikidata":"https://www.wikidata.org/wiki/Q318623","display_name":"Myofibril","level":2,"score":0.8300912380218506},{"id":"https://openalex.org/C68731436","wikidata":"https://www.wikidata.org/wiki/Q1337087","display_name":"Sarcomere","level":3,"score":0.7995490431785583},{"id":"https://openalex.org/C199096232","wikidata":"https://www.wikidata.org/wiki/Q1545001","display_name":"Sarcolemma","level":3,"score":0.7044349908828735},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6985985636711121},{"id":"https://openalex.org/C174054327","wikidata":"https://www.wikidata.org/wiki/Q6947920","display_name":"Myofilament","level":3,"score":0.626867949962616},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4900726079940796},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.48523974418640137},{"id":"https://openalex.org/C2776050358","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Muscle contraction","level":2,"score":0.48233935236930847},{"id":"https://openalex.org/C139966638","wikidata":"https://www.wikidata.org/wiki/Q597678","display_name":"Sarcoplasm","level":3,"score":0.4498981535434723},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43197399377822876},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.33195817470550537},{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.29842129349708557},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15948325395584106}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003593","descriptor_name":"Cytoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009210","descriptor_name":"Myofibrils","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012508","descriptor_name":"Sarcolemma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012518","descriptor_name":"Sarcomeres","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012519","descriptor_name":"Sarcoplasmic Reticulum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014617","descriptor_name":"Vacuoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1083/jcb.3.2.269","doi":"https://doi.org/10.1083/jcb.3.2.269","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.3.2.269","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2224093","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2224093/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2224093/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biophys Biochem Cytol","raw_type":"Text"},{"id":"pmid:13438910","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13438910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biophysical and biochemical cytology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.283.555","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.283.555","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/26/68/J_Biophys_Biochem_Cytol_1957_Mar_25_3(2)_269-300.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2224093","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2224093/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2224093/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biophys Biochem Cytol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978660000.pdf","grobid_xml":"https://content.openalex.org/works/W1978660000.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1909608893","https://openalex.org/W1967446117","https://openalex.org/W1967669192","https://openalex.org/W1975714515","https://openalex.org/W1976274501","https://openalex.org/W1978592930","https://openalex.org/W1981414344","https://openalex.org/W1993244362","https://openalex.org/W2013040830","https://openalex.org/W2015869517","https://openalex.org/W2028013633","https://openalex.org/W2038011170","https://openalex.org/W2039462254","https://openalex.org/W2041690975","https://openalex.org/W2044564000","https://openalex.org/W2046648056","https://openalex.org/W2059114383","https://openalex.org/W2064644667","https://openalex.org/W2072557123","https://openalex.org/W2074386103","https://openalex.org/W2075672604","https://openalex.org/W2080669995","https://openalex.org/W2083745906","https://openalex.org/W2089114409","https://openalex.org/W2100666197","https://openalex.org/W2105083616","https://openalex.org/W2109218888","https://openalex.org/W2155520261","https://openalex.org/W2155555309","https://openalex.org/W2162734772","https://openalex.org/W2336063556","https://openalex.org/W2394979757","https://openalex.org/W2396920825","https://openalex.org/W2413562744","https://openalex.org/W2415753296","https://openalex.org/W2427949933","https://openalex.org/W2470885307","https://openalex.org/W2491728498"],"related_works":["https://openalex.org/W2155555309","https://openalex.org/W2024305870","https://openalex.org/W7099260321","https://openalex.org/W1495350220","https://openalex.org/W7095799176","https://openalex.org/W2069738178","https://openalex.org/W2075837868","https://openalex.org/W2025691829","https://openalex.org/W4230492470","https://openalex.org/W2409021161"],"abstract_inverted_index":{"Several":[0],"types":[1],"of":[2,11,20,28,45,65,94,109,114,151,165,174,182,235],"striated":[3],"muscle":[4,27,204],"have":[5],"been":[6,40],"examined":[7],"by":[8],"the":[9,15,23,29,46,60,82,95,99,107,110,139,142,154,157,166,171,183,186,191,195,198,213,216,221,225,232,236],"technics":[10],"electron":[12],"microscopy":[13],"and":[14,25,49,69,125,131,146,159,223],"findings":[16],"in":[17,34,72,104,121,153,203,231],"myotome":[18],"fibers":[19],"Amblystoma":[21],"larvae,":[22],"sartorius,":[24],"cardiac":[26],"rat":[30],"are":[31,118],"reported":[32],"on":[33,127],"some":[35],"detail.":[36],"Particular":[37],"attention":[38],"has":[39],"given":[41],"to":[42,52,170,185],"structural":[43],"components":[44],"interfibrillar":[47],"sarcoplasm":[48],"most":[50],"especially":[51],"a":[53,73,86],"finely":[54],"divided,":[55],"vacuolar":[56],"system":[57,101,135,167,199,217],"known":[58],"as":[59],"sarcoplasmic":[61],"reticulum.":[62],"This":[63],"consists":[64],"membrane-limited":[66],"vesicles,":[67],"tubules,":[68],"cisternae":[70],"associated":[71,111],"continuous":[74,137],"reticular":[75],"structure":[76,155,164],"which":[77,89],"forms":[78],"lace-like":[79],"sleeves":[80],"around":[81],"myofibrils.":[83,112],"It":[84],"shows":[85],"definable":[87],"organization":[88],"repeats":[90],"with":[91,106,188],"each":[92],"sarcomere":[93],"fiber":[96,140],"so":[97],"that":[98,197,212,224],"entire":[100],"is":[102,136,200,210,218,229],"segmented":[103],"phase":[105],"striations":[108],"Details":[113],"these":[115],"repetitive":[116],"patterns":[117],"presented":[119],"diagrammatically":[120],"Text-figs.":[122],"1,":[123],"2,":[124],"3":[126],"pages":[128],"279,":[129],"283,":[130],"288":[132],"respectively.":[133],"The":[134,163,178],"across":[138],"at":[141,156],"H":[143],"band":[144,161],"level":[145],"largely":[147],"discontinuous":[148],"longitudinally":[149],"because":[150],"interruptions":[152],"I":[158],"Z":[160],"levels.":[162],"relates":[168],"it":[169,209],"endoplasmic":[172],"reticulum":[173,184],"other":[175],"cell":[176],"types.":[177],"precise":[179],"morphological":[180],"relation":[181],"myofibrils,":[187],"specializations":[189],"opposite":[190],"different":[192],"bands,":[193],"prompts":[194],"supposition":[196],"functionally":[201],"important":[202],"contraction.":[205],"In":[206],"this":[207],"regard":[208],"proposed":[211],"membrane":[214],"limiting":[215],"polarized":[219],"like":[220],"sarcolemma":[222],"corresponding":[226],"potential":[227],"difference":[228],"utilized":[230],"intracellular":[233],"distribution":[234],"excitatory":[237],"impulse.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":17},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}