{"id":"https://openalex.org/W1978618471","doi":"https://doi.org/10.1006/abio.2001.5565","title":"Accessing Single Nucleotide Polymorphisms in Genomic DNA by Direct Multiplex Polymerase Chain Reaction Amplification on Oligonucleotide Microarrays","display_name":"Accessing Single Nucleotide Polymorphisms in Genomic DNA by Direct Multiplex Polymerase Chain Reaction Amplification on Oligonucleotide Microarrays","publication_year":2002,"publication_date":"2002-04-01","ids":{"openalex":"https://openalex.org/W1978618471","doi":"https://doi.org/10.1006/abio.2001.5565","mag":"1978618471","pmid":"https://pubmed.ncbi.nlm.nih.gov/11906147"},"language":"en","primary_location":{"id":"doi:10.1006/abio.2001.5565","doi":"https://doi.org/10.1006/abio.2001.5565","is_oa":false,"landing_page_url":"https://doi.org/10.1006/abio.2001.5565","pdf_url":null,"source":{"id":"https://openalex.org/S7858788","display_name":"Analytical Biochemistry","issn_l":"0003-2697","issn":["0003-2697","1096-0309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104956072","display_name":"Martin Huber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142901","display_name":"Vienna Biocenter","ror":"https://ror.org/04khwmr87","country_code":"AT","type":"other","lineage":["https://openalex.org/I4210142901"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Martin Huber","raw_affiliation_strings":["VBC-GENOMICS Bioscience Research GmbH, Rennweg 95b/5, A-1030 Vienna, Austria","VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, Rennweg 95b/5, A-1030 Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]},{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004779007","display_name":"Axel Muendlein","orcid":"https://orcid.org/0000-0002-5582-4125","observed_orcids":["https://orcid.org/0000-0002-5582-4125"]},"institutions":[{"id":"https://openalex.org/I4210142901","display_name":"Vienna Biocenter","ror":"https://ror.org/04khwmr87","country_code":"AT","type":"other","lineage":["https://openalex.org/I4210142901"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Axel M\u00fcndlein","raw_affiliation_strings":["VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011645931","display_name":"Eva Dornstauder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142901","display_name":"Vienna Biocenter","ror":"https://ror.org/04khwmr87","country_code":"AT","type":"other","lineage":["https://openalex.org/I4210142901"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Eva Dornstauder","raw_affiliation_strings":["VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061491532","display_name":"Christian Schneeberger","orcid":"https://orcid.org/0000-0002-7997-8014","observed_orcids":["https://orcid.org/0000-0002-7997-8014"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christian Schneeberger","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Vienna, Medical School, 1090, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Vienna, Medical School, 1090, Vienna, Austria","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014109887","display_name":"Cle\ufeffmens Tempfer","orcid":"https://orcid.org/0000-0002-6904-3258","observed_orcids":["https://orcid.org/0000-0002-6904-3258"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Clemens B. Tempfer","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Vienna, Medical School, 1090, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Vienna, Medical School, 1090, Vienna, Austria","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007190717","display_name":"Manfred W. Mueller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142901","display_name":"Vienna Biocenter","ror":"https://ror.org/04khwmr87","country_code":"AT","type":"other","lineage":["https://openalex.org/I4210142901"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Manfred W. Mueller","raw_affiliation_strings":["VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081535653","display_name":"Wolfgang M. Schmidt","orcid":"https://orcid.org/0000-0002-6944-2443","observed_orcids":["https://orcid.org/0000-0002-6944-2443"]},"institutions":[{"id":"https://openalex.org/I4210142901","display_name":"Vienna Biocenter","ror":"https://ror.org/04khwmr87","country_code":"AT","type":"other","lineage":["https://openalex.org/I4210142901"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Wolfgang M. Schmidt","raw_affiliation_strings":["VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VBC-GENOMICS Bioscience Research GmbH, 1030, Vienna, Austria","institution_ids":["https://openalex.org/I4210142901"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5081535653"],"corresponding_institution_ids":["https://openalex.org/I4210142901"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":3.7286,"has_fulltext":false,"cited_by_count":81,"citation_normalized_percentile":{"value":0.94457454,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"303","issue":"1","first_page":"25","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.23579999804496765,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.04699999839067459,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9890000224113464},{"id":"https://openalex.org/keywords/snp-genotyping","display_name":"SNP genotyping","score":0.9620000123977661},{"id":"https://openalex.org/keywords/dna-microarrays","display_name":"DNA microarrays","score":0.7850000262260437},{"id":"https://openalex.org/keywords/multiplex-pcr","display_name":"multiplex PCR","score":0.8460000157356262},{"id":"https://openalex.org/keywords/allele-specific-pcr","display_name":"allele-specific PCR","score":0.6899999976158142},{"id":"https://openalex.org/keywords/solid-phase-pcr","display_name":"solid-phase PCR","score":0.6200000047683716},{"id":"https://openalex.org/keywords/fluorescence-scanning","display_name":"fluorescence scanning","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.8052718639373779},{"id":"https://openalex.org/C163691529","wikidata":"https://www.wikidata.org/wiki/Q7391886","display_name":"SNP genotyping","level":5,"score":0.7372617721557617},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.6983546018600464},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.6699156761169434},{"id":"https://openalex.org/C90583042","wikidata":"https://www.wikidata.org/wiki/Q1952456","display_name":"Multiplex polymerase chain reaction","level":4,"score":0.6277642250061035},{"id":"https://openalex.org/C17757408","wikidata":"https://www.wikidata.org/wiki/Q4135516","display_name":"genomic DNA","level":3,"score":0.617777943611145},{"id":"https://openalex.org/C59701697","wikidata":"https://www.wikidata.org/wiki/Q6895959","display_name":"Molecular Inversion Probe","level":5,"score":0.6030899882316589},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5858277082443237},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.5687774419784546},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5670260190963745},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5579351782798767},{"id":"https://openalex.org/C54887055","wikidata":"https://www.wikidata.org/wiki/Q5205758","display_name":"DNA nanoball sequencing","level":5,"score":0.5074319243431091},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5026693344116211},{"id":"https://openalex.org/C156385826","wikidata":"https://www.wikidata.org/wiki/Q1341059","display_name":"Multiple displacement amplification","level":5,"score":0.4738609790802002},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4665166139602661},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.45669159293174744},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.42734047770500183},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35317546129226685},{"id":"https://openalex.org/C13575015","wikidata":"https://www.wikidata.org/wiki/Q1562492","display_name":"Genomic library","level":4,"score":0.2002471387386322},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1950499713420868},{"id":"https://openalex.org/C78063203","wikidata":"https://www.wikidata.org/wiki/Q3062596","display_name":"DNA extraction","level":4,"score":0.15042436122894287},{"id":"https://openalex.org/C3017666073","wikidata":"https://www.wikidata.org/wiki/Q1764062","display_name":"Base sequence","level":3,"score":0.06917068362236023},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1006/abio.2001.5565","doi":"https://doi.org/10.1006/abio.2001.5565","is_oa":false,"landing_page_url":"https://doi.org/10.1006/abio.2001.5565","pdf_url":null,"source":{"id":"https://openalex.org/S7858788","display_name":"Analytical Biochemistry","issn_l":"0003-2697","issn":["0003-2697","1096-0309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Biochemistry","raw_type":"journal-article"},{"id":"pmid:11906147","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11906147","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1499500424","https://openalex.org/W1974960276","https://openalex.org/W1975188059","https://openalex.org/W1992348777","https://openalex.org/W2018347065","https://openalex.org/W2020860003","https://openalex.org/W2025597030","https://openalex.org/W2034270708","https://openalex.org/W2036383542","https://openalex.org/W2036469722","https://openalex.org/W2037509330","https://openalex.org/W2042419359","https://openalex.org/W2059667789","https://openalex.org/W2082047757","https://openalex.org/W2083674311","https://openalex.org/W2103794559","https://openalex.org/W2105025553","https://openalex.org/W2108638990","https://openalex.org/W2108861052","https://openalex.org/W2122732537","https://openalex.org/W2130974514","https://openalex.org/W2140107851","https://openalex.org/W2162426408","https://openalex.org/W2168783815","https://openalex.org/W2227655822","https://openalex.org/W2978334699","https://openalex.org/W4230538884","https://openalex.org/W6629874611","https://openalex.org/W7034241361"],"related_works":["https://openalex.org/W2121308112","https://openalex.org/W2153437712","https://openalex.org/W2409733948","https://openalex.org/W2201466581","https://openalex.org/W2120512069","https://openalex.org/W1487000026","https://openalex.org/W1756257127","https://openalex.org/W2113311913","https://openalex.org/W7096267458","https://openalex.org/W287645300"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}