{"id":"https://openalex.org/W1978525919","doi":"https://doi.org/10.1021/jf400283w","title":"Effects of Pectin Pentaoligosaccharide from Hawthorn (Crataegus pinnatifida Bunge. var. Major) on the Activity and mRNA Levels of Enzymes Involved in Fatty Acid Oxidation in the Liver of Mice Fed a High-Fat Diet","display_name":"Effects of Pectin Pentaoligosaccharide from Hawthorn (Crataegus pinnatifida Bunge. var. Major) on the Activity and mRNA Levels of Enzymes Involved in Fatty Acid Oxidation in the Liver of Mice Fed a High-Fat Diet","publication_year":2013,"publication_date":"2013-07-15","ids":{"openalex":"https://openalex.org/W1978525919","doi":"https://doi.org/10.1021/jf400283w","mag":"1978525919","pmid":"https://pubmed.ncbi.nlm.nih.gov/23855516"},"language":"en","primary_location":{"id":"doi:10.1021/jf400283w","doi":"https://doi.org/10.1021/jf400283w","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf400283w","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090196232","display_name":"Tuoping Li","orcid":"https://orcid.org/0000-0001-9195-1378","observed_orcids":["https://orcid.org/0000-0001-9195-1378"]},"institutions":[{"id":"https://openalex.org/I118803816","display_name":"Liaoning University","ror":"https://ror.org/03xpwj629","country_code":"CN","type":"education","lineage":["https://openalex.org/I118803816"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Tuo-ping Li","raw_affiliation_strings":["Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","Department of Food Science, Liaoning University ,; The Engineering Technology Research Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory of Food Bioprocessing and Quality Control Technology, Shenyang 110036, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","institution_ids":["https://openalex.org/I118803816"]},{"raw_affiliation_string":"Department of Food Science, Liaoning University ,; The Engineering Technology Research Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory of Food Bioprocessing and Quality Control Technology, Shenyang 110036, China","institution_ids":["https://openalex.org/I118803816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101539922","display_name":"Rugang Zhu","orcid":"https://orcid.org/0000-0003-0731-868X","observed_orcids":["https://orcid.org/0000-0003-0731-868X"]},"institutions":[{"id":"https://openalex.org/I118803816","display_name":"Liaoning University","ror":"https://ror.org/03xpwj629","country_code":"CN","type":"education","lineage":["https://openalex.org/I118803816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ru-gang Zhu","raw_affiliation_strings":["Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","institution_ids":["https://openalex.org/I118803816"]},{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China","institution_ids":["https://openalex.org/I118803816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101396271","display_name":"Yinping Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118803816","display_name":"Liaoning University","ror":"https://ror.org/03xpwj629","country_code":"CN","type":"education","lineage":["https://openalex.org/I118803816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin-ping Dong","raw_affiliation_strings":["Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","institution_ids":["https://openalex.org/I118803816"]},{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China","institution_ids":["https://openalex.org/I118803816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100622984","display_name":"Yonghui Liu","orcid":"https://orcid.org/0000-0002-0875-8604","observed_orcids":["https://orcid.org/0000-0002-0875-8604"]},"institutions":[{"id":"https://openalex.org/I118803816","display_name":"Liaoning University","ror":"https://ror.org/03xpwj629","country_code":"CN","type":"education","lineage":["https://openalex.org/I118803816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong-hui Liu","raw_affiliation_strings":["Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research\rCenter for Food Bioprocessing of Liaoning Province; and The Key Laboratory\rof Food Bioprocessing and Quality Control Technology, Shenyang 110036,\rChina","institution_ids":["https://openalex.org/I118803816"]},{"raw_affiliation_string":"Department of Food Science, Liaoning University,; The Engineering Technology Research#R#Center for Food Bioprocessing of Liaoning Province; and The Key Laboratory#R#of Food Bioprocessing and Quality Control Technology, Shenyang 110036,#R#China","institution_ids":["https://openalex.org/I118803816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041038107","display_name":"Suhong Li","orcid":"https://orcid.org/0000-0002-3838-6952","observed_orcids":["https://orcid.org/0000-0002-3838-6952"]},"institutions":[{"id":"https://openalex.org/I32399674","display_name":"Shenyang Normal University","ror":"https://ror.org/05cdfgm80","country_code":"CN","type":"education","lineage":["https://openalex.org/I32399674"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Su-hong Li","raw_affiliation_strings":["Department of Food\rScience, Shenyang Normal University, Shenyang\r110034, China","Department of Food#R#Science, Shenyang Normal University, Shenyang#R#110034, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food\rScience, Shenyang Normal University, Shenyang\r110034, China","institution_ids":["https://openalex.org/I32399674"]},{"raw_affiliation_string":"Department of Food#R#Science, Shenyang Normal University, Shenyang#R#110034, China","institution_ids":["https://openalex.org/I32399674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100636770","display_name":"Gang Chen","orcid":"https://orcid.org/0000-0001-9151-0847","observed_orcids":["https://orcid.org/0000-0001-9151-0847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gang Chen","raw_affiliation_strings":["Forestry Biotechnology\rand Analysis\rTest Center, Liaoning Academy of Forestry Sciences, Shenyang 110032, China","Forestry Biotechnology#R#and Analysis#R#Test Center, Liaoning Academy of Forestry Sciences, Shenyang 110032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Forestry Biotechnology\rand Analysis\rTest Center, Liaoning Academy of Forestry Sciences, Shenyang 110032, China","institution_ids":[]},{"raw_affiliation_string":"Forestry Biotechnology#R#and Analysis#R#Test Center, Liaoning Academy of Forestry Sciences, Shenyang 110032, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5090196232"],"corresponding_institution_ids":["https://openalex.org/I118803816"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":5.2307,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.94750981,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"61","issue":"31","first_page":"7599","last_page":"7605"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13238","display_name":"Botanical Studies and Applications","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13238","display_name":"Botanical Studies and Applications","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":0.10729999840259552,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12489","display_name":"Microbial Metabolites in Food Biotechnology","score":0.06459999829530716,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crataegus-pinnatifida","display_name":"Crataegus pinnatifida","score":0.9470000267028809},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.8489999771118164},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.6769999861717224},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.9860000014305115},{"id":"https://openalex.org/keywords/acyl-coa-oxidase","display_name":"acyl-CoA oxidase","score":0.906000018119812},{"id":"https://openalex.org/keywords/carnitine-palmitoyltransferase-1","display_name":"carnitine palmitoyltransferase 1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/3-ketoacyl-coa-thiolase","display_name":"3-ketoacyl-CoA thiolase","score":0.9900000095367432},{"id":"https://openalex.org/keywords/2-4-dienoyl-coa-reductase","display_name":"2,4-dienoyl-CoA reductase","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pparalpha","display_name":"PPAR\u03b1","score":0.949999988079071},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.6240000128746033},{"id":"https://openalex.org/keywords/serum-triglycerides","display_name":"serum triglycerides","score":0.8840000033378601},{"id":"https://openalex.org/keywords/fecal-fat-excretion","display_name":"fecal fat excretion","score":0.9760000109672546},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6370000243186951},{"id":"https://openalex.org/keywords/cardiovascular-disease-prevention","display_name":"cardiovascular disease prevention","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2781031557","wikidata":"https://www.wikidata.org/wiki/Q24782380","display_name":"Thiolase","level":4,"score":0.6860948801040649},{"id":"https://openalex.org/C127078168","wikidata":"https://www.wikidata.org/wiki/Q138639","display_name":"Peroxisome","level":3,"score":0.621568500995636},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5668537020683289},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5615193843841553},{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.5458084940910339},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5313278436660767},{"id":"https://openalex.org/C2778435403","wikidata":"https://www.wikidata.org/wiki/Q243309","display_name":"Carnitine","level":2,"score":0.4987905025482178},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.494490385055542},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.487899512052536},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.4657025933265686},{"id":"https://openalex.org/C48289651","wikidata":"https://www.wikidata.org/wiki/Q106916817","display_name":"Fatty acid synthase","level":3,"score":0.42982175946235657},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35867416858673096},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.28040042519569397},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25936391949653625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15056738257408142}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002334","descriptor_name":"Carnitine O-Palmitoyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002334","descriptor_name":"Carnitine O-Palmitoyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002334","descriptor_name":"Carnitine O-Palmitoyltransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010368","descriptor_name":"Pectins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010368","descriptor_name":"Pectins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010368","descriptor_name":"Pectins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D027825","descriptor_name":"Crataegus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D027825","descriptor_name":"Crataegus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D027825","descriptor_name":"Crataegus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D042962","descriptor_name":"Acyl-CoA Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042962","descriptor_name":"Acyl-CoA Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042962","descriptor_name":"Acyl-CoA Oxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044925","descriptor_name":"Oxidoreductases Acting on CH-CH Group Donors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044925","descriptor_name":"Oxidoreductases Acting on CH-CH Group Donors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044925","descriptor_name":"Oxidoreductases Acting on CH-CH Group Donors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/jf400283w","doi":"https://doi.org/10.1021/jf400283w","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jf400283w","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},{"id":"pmid:23855516","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23855516","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of agricultural and food chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W83408023","https://openalex.org/W1834303186","https://openalex.org/W1909040817","https://openalex.org/W1964834484","https://openalex.org/W1965867257","https://openalex.org/W1966654138","https://openalex.org/W1966786144","https://openalex.org/W1967923229","https://openalex.org/W1968834637","https://openalex.org/W1969734540","https://openalex.org/W1978125779","https://openalex.org/W1979026271","https://openalex.org/W1981722355","https://openalex.org/W1981982211","https://openalex.org/W1986218237","https://openalex.org/W1989824965","https://openalex.org/W1991487270","https://openalex.org/W2001513552","https://openalex.org/W2004184623","https://openalex.org/W2010002703","https://openalex.org/W2010360119","https://openalex.org/W2016141715","https://openalex.org/W2024173696","https://openalex.org/W2029566261","https://openalex.org/W2038177557","https://openalex.org/W2041792049","https://openalex.org/W2051711682","https://openalex.org/W2056658749","https://openalex.org/W2058571343","https://openalex.org/W2072029917","https://openalex.org/W2083226856","https://openalex.org/W2084910749","https://openalex.org/W2094292815","https://openalex.org/W2097714259","https://openalex.org/W2104492370","https://openalex.org/W2111313276","https://openalex.org/W2128635872","https://openalex.org/W2129456939","https://openalex.org/W2131955003","https://openalex.org/W2134467287","https://openalex.org/W2136823038","https://openalex.org/W2145089546","https://openalex.org/W2148574834","https://openalex.org/W2154272456","https://openalex.org/W2160518844","https://openalex.org/W2168526937","https://openalex.org/W2169185606","https://openalex.org/W2324425660"],"related_works":["https://openalex.org/W2085825136","https://openalex.org/W1966774090","https://openalex.org/W2027647762","https://openalex.org/W2000673671","https://openalex.org/W2063649303","https://openalex.org/W1974662072","https://openalex.org/W2784805033","https://openalex.org/W4236863202","https://openalex.org/W2083701549","https://openalex.org/W2083020417"],"abstract_inverted_index":{"The":[0],"regulatory":[1],"effects":[2],"of":[3,22,104,146],"haw":[4],"pectin":[5],"pentaoligosaccharide":[6],"(HPPS)":[7],"on":[8],"fatty":[9,99],"acid":[10,100],"oxidation-related":[11,101],"enzyme":[12,102],"activities":[13,103],"and":[14,45,53,64,70,79,112,119,132,143,166],"mRNA":[15],"levels":[16,60],"were":[17,126],"investigated":[18],"in":[19,74],"the":[20,97,123,141],"liver":[21],"high":[23],"fat":[24],"diet":[25,52,91],"induced":[26],"hyperlipidemic":[27],"mice.":[28],"Results":[29,151],"showed":[30],"that":[31,153],"HPPS":[32,54,94,136,155],"(150":[33],"mg/kg":[34],"for":[35,50,84],"10":[36],"weeks)":[37],"significantly":[38,95],"suppresses":[39],"weight":[40],"gain":[41],"(32.3":[42],"\u00b1":[43,47,62,66,77,81],"0.26":[44],"21.1":[46],"0.14":[48],"g":[49],"high-fat":[51,90],"groups,":[55],"respectively),":[56,69,87],"decreases":[57],"serum":[58],"triacylglycerol":[59],"(1.64":[61],"0.09":[63],"0.91":[65],"0.02":[67],"mmol/L,":[68],"increases":[71],"lipid":[72],"excretion":[73],"feces":[75],"(55.7":[76],"0.38":[78],"106.4":[80],"0.57":[82],"mg/g":[83],"total":[85],"lipid,":[86],"compared":[88],"to":[89,139,163],"as":[92,160],"control.":[93],"increased":[96],"hepatic":[98],"acyl-CoA":[105],"oxidase,":[106],"carnitine":[107],"palmitoyltransferase":[108],"I,":[109],"3-ketoacyl-CoA":[110],"thiolase,":[111],"2,4-dienoyl-CoA":[113],"reductase":[114],"by":[115,128],"53.8,":[116],"74.2,":[117],"47.1,":[118],"24.2%,":[120],"respectively.":[121,134],"Meanwhile,":[122],"corresponding":[124],"mRNAs":[125],"up-regulated":[127],"89.6,":[129],"85.8,":[130],"82.9,":[131],"30.9%,":[133],"Moreover,":[135],"was":[137],"able":[138],"up-regulate":[140],"gene":[142],"protein":[144],"expressions":[145],"peroxisome":[147],"proliferator-activated":[148],"receptor":[149],"\u03b1.":[150],"suggest":[152],"continuous":[154],"ingestion":[156],"may":[157],"be":[158],"used":[159],"dietary":[161],"therapy":[162],"prevent":[164],"obesity":[165],"cardiovascular":[167],"diseases.":[168]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}