{"id":"https://openalex.org/W1978491570","doi":"https://doi.org/10.1016/0306-4522(95)00583-8","title":"Apomorphine and dopamine D1 receptor agonists increase the firing rates of subthalamic nucleus neurons","display_name":"Apomorphine and dopamine D1 receptor agonists increase the firing rates of subthalamic nucleus neurons","publication_year":1996,"publication_date":"1996-06-01","ids":{"openalex":"https://openalex.org/W1978491570","doi":"https://doi.org/10.1016/0306-4522(95)00583-8","mag":"1978491570","pmid":"https://pubmed.ncbi.nlm.nih.gov/9157332"},"language":"en","primary_location":{"id":"doi:10.1016/0306-4522(95)00583-8","doi":"https://doi.org/10.1016/0306-4522(95)00583-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4522(95)00583-8","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049697442","display_name":"Deborah S. Kreiss","orcid":"https://orcid.org/0009-0006-7070-6625","observed_orcids":["https://orcid.org/0009-0006-7070-6625"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.S. Kreiss","raw_affiliation_strings":["Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1406, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1406, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L.A. Anderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.A. Anderson","raw_affiliation_strings":["Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5C-103, 9000 Rockville Pike, Bethesda, MD 20892-1406, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5C-103, 9000 Rockville Pike, Bethesda, MD 20892-1406, U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034511392","display_name":"Judith R. Walters","orcid":"https://orcid.org/0000-0002-9192-5222","observed_orcids":["https://orcid.org/0000-0002-9192-5222"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J.R. Walters","raw_affiliation_strings":["Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5C-103, 9000 Rockville Pike, Bethesda, MD 20892-1406, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5C-103, 9000 Rockville Pike, Bethesda, MD 20892-1406, U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034511392"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":6.2892,"has_fulltext":false,"cited_by_count":123,"citation_normalized_percentile":{"value":0.96702207,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"72","issue":"3","first_page":"863","last_page":"876"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.03779999911785126,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subthalamic-nucleus","display_name":"subthalamic nucleus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dopamine-d1-receptor","display_name":"dopamine D1 receptor","score":0.7940000295639038},{"id":"https://openalex.org/keywords/apomorphine","display_name":"apomorphine","score":0.9729999899864197},{"id":"https://openalex.org/keywords/quinpirole","display_name":"quinpirole","score":0.8899999856948853},{"id":"https://openalex.org/keywords/skf-38393","display_name":"SKF 38393","score":0.9330000281333923},{"id":"https://openalex.org/keywords/skf-82958","display_name":"SKF 82958","score":0.9919999837875366},{"id":"https://openalex.org/keywords/sch-23390","display_name":"SCH 23390","score":0.9829999804496765},{"id":"https://openalex.org/keywords/neuronal-firing-rate","display_name":"neuronal firing rate","score":0.8600000143051147},{"id":"https://openalex.org/keywords/basal-ganglia","display_name":"basal ganglia","score":0.8730000257492065},{"id":"https://openalex.org/keywords/basal-ganglia-output","display_name":"basal ganglia output","score":0.7829999923706055},{"id":"https://openalex.org/keywords/dopamine-agonists","display_name":"dopamine agonists","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C2777319143","wikidata":"https://www.wikidata.org/wiki/Q2270424","display_name":"Subthalamic nucleus","level":5,"score":0.8742608428001404},{"id":"https://openalex.org/C2777525119","wikidata":"https://www.wikidata.org/wiki/Q269111","display_name":"Apomorphine","level":4,"score":0.7228462100028992},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.598402738571167},{"id":"https://openalex.org/C2778296116","wikidata":"https://www.wikidata.org/wiki/Q253187","display_name":"Quinpirole","level":4,"score":0.59088134765625},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.468289315700531},{"id":"https://openalex.org/C120069818","wikidata":"https://www.wikidata.org/wiki/Q415496","display_name":"Dopamine receptor","level":3,"score":0.4516441524028778},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.4429372251033783},{"id":"https://openalex.org/C44208683","wikidata":"https://www.wikidata.org/wiki/Q15335165","display_name":"Dopamine receptor D2","level":3,"score":0.41472291946411133},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4001380205154419},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3579727113246918},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32354897260665894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.273730993270874},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.25218507647514343},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.22092130780220032},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.14181414246559143},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.12386110424995422},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001058","descriptor_name":"Apomorphine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001345","descriptor_name":"Autoradiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013787","descriptor_name":"Thalamic Nuclei","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015647","descriptor_name":"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0306-4522(95)00583-8","doi":"https://doi.org/10.1016/0306-4522(95)00583-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0306-4522(95)00583-8","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},{"id":"pmid:9157332","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9157332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":105,"referenced_works":["https://openalex.org/W184200768","https://openalex.org/W249845531","https://openalex.org/W586370793","https://openalex.org/W633589597","https://openalex.org/W1768450208","https://openalex.org/W1884206649","https://openalex.org/W1910271960","https://openalex.org/W1965537515","https://openalex.org/W1966577272","https://openalex.org/W1973620174","https://openalex.org/W1976045951","https://openalex.org/W1979098045","https://openalex.org/W1980411146","https://openalex.org/W1980489779","https://openalex.org/W1982827121","https://openalex.org/W1983659655","https://openalex.org/W1984340210","https://openalex.org/W1984511977","https://openalex.org/W1986727719","https://openalex.org/W1987024745","https://openalex.org/W1987911844","https://openalex.org/W1988619576","https://openalex.org/W1988836643","https://openalex.org/W1989058665","https://openalex.org/W1990280414","https://openalex.org/W1992316798","https://openalex.org/W1995183156","https://openalex.org/W1997113789","https://openalex.org/W1997543830","https://openalex.org/W2002859264","https://openalex.org/W2003703317","https://openalex.org/W2011513679","https://openalex.org/W2011737473","https://openalex.org/W2013316323","https://openalex.org/W2019981460","https://openalex.org/W2021683549","https://openalex.org/W2023297242","https://openalex.org/W2024136403","https://openalex.org/W2028091796","https://openalex.org/W2028373322","https://openalex.org/W2028466783","https://openalex.org/W2031268318","https://openalex.org/W2032242647","https://openalex.org/W2033412830","https://openalex.org/W2036363236","https://openalex.org/W2039209240","https://openalex.org/W2039364302","https://openalex.org/W2039724227","https://openalex.org/W2039950820","https://openalex.org/W2040113239","https://openalex.org/W2043393596","https://openalex.org/W2044066882","https://openalex.org/W2044530383","https://openalex.org/W2047575016","https://openalex.org/W2049356275","https://openalex.org/W2050580902","https://openalex.org/W2053727139","https://openalex.org/W2056404977","https://openalex.org/W2057584841","https://openalex.org/W2057788173","https://openalex.org/W2059387706","https://openalex.org/W2060588252","https://openalex.org/W2065124234","https://openalex.org/W2066926328","https://openalex.org/W2066942245","https://openalex.org/W2068020919","https://openalex.org/W2074402500","https://openalex.org/W2074616189","https://openalex.org/W2075926563","https://openalex.org/W2076509976","https://openalex.org/W2078014006","https://openalex.org/W2079288340","https://openalex.org/W2080782023","https://openalex.org/W2081141578","https://openalex.org/W2081963528","https://openalex.org/W2084676667","https://openalex.org/W2085877827","https://openalex.org/W2086131200","https://openalex.org/W2087294379","https://openalex.org/W2087688448","https://openalex.org/W2091293272","https://openalex.org/W2091914373","https://openalex.org/W2113320486","https://openalex.org/W2136682365","https://openalex.org/W2137123069","https://openalex.org/W2138856840","https://openalex.org/W2142038349","https://openalex.org/W2159082363","https://openalex.org/W2163815564","https://openalex.org/W2170612253","https://openalex.org/W2176873872","https://openalex.org/W2177298617","https://openalex.org/W2255081356","https://openalex.org/W2290621392","https://openalex.org/W2297875861","https://openalex.org/W2402507191","https://openalex.org/W2414457638","https://openalex.org/W2499745540","https://openalex.org/W4238226939","https://openalex.org/W6640104688","https://openalex.org/W6657623599","https://openalex.org/W6676654253","https://openalex.org/W6691878476","https://openalex.org/W6696512750","https://openalex.org/W6697593969"],"related_works":["https://openalex.org/W2141101235","https://openalex.org/W1990168633","https://openalex.org/W2068970795","https://openalex.org/W1883604772","https://openalex.org/W2037853650","https://openalex.org/W2051536308","https://openalex.org/W2084497923","https://openalex.org/W2059370679","https://openalex.org/W1997162743","https://openalex.org/W2096757255"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}