{"id":"https://openalex.org/W1978446723","doi":"https://doi.org/10.4102/sajhivmed.v14i3.70","title":"MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis","display_name":"MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis","publication_year":2013,"publication_date":"2013-09-17","ids":{"openalex":"https://openalex.org/W1978446723","doi":"https://doi.org/10.4102/sajhivmed.v14i3.70","mag":"1978446723"},"language":"en","primary_location":{"id":"doi:10.4102/sajhivmed.v14i3.70","doi":"https://doi.org/10.4102/sajhivmed.v14i3.70","is_oa":true,"landing_page_url":"https://doi.org/10.4102/sajhivmed.v14i3.70","pdf_url":"https://sajhivmed.org.za/index.php/hivmed/article/download/70/106","source":{"id":"https://openalex.org/S74263619","display_name":"Southern African Journal of HIV Medicine","issn_l":"1608-9693","issn":["1608-9693","2078-6751"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","doyens","jpps-2","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315322","host_organization_name":"AOSIS","host_organization_lineage":["https://openalex.org/P4310315322"],"host_organization_lineage_names":["AOSIS"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern African Journal of HIV Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://sajhivmed.org.za/index.php/hivmed/article/download/70/106","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048757261","display_name":"James E. Scriven","orcid":"https://orcid.org/0000-0001-8463-7137","observed_orcids":["https://orcid.org/0000-0001-8463-7137"]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]},{"id":"https://openalex.org/I194839184","display_name":"Liverpool School of Tropical Medicine","ror":"https://ror.org/03svjbs84","country_code":"GB","type":"other","lineage":["https://openalex.org/I194839184"]},{"id":"https://openalex.org/I4405266898","display_name":"Institute of Infectious Disease and Molecular Medicine","ror":"https://ror.org/00900dw59","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274","https://openalex.org/I4405266898"]}],"countries":["GB","ZA"],"is_corresponding":false,"raw_author_name":"J Scriven","raw_affiliation_strings":["Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; Liverpool School of Tropical Medicine, Liverpool, United Kingdom","Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa","Liverpool School of Tropical Medicine, Liverpool, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; Liverpool School of Tropical Medicine, Liverpool, United Kingdom","institution_ids":["https://openalex.org/I157614274","https://openalex.org/I194839184","https://openalex.org/I4405266898"]},{"raw_affiliation_string":"Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274","https://openalex.org/I4405266898"]},{"raw_affiliation_string":"Liverpool School of Tropical Medicine, Liverpool, United Kingdom","institution_ids":["https://openalex.org/I194839184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112613402","display_name":"Jacqui Cirota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"J Cirota","raw_affiliation_strings":["Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088188014","display_name":"Charle Andre Viljoen","orcid":"https://orcid.org/0000-0001-7246-4136","observed_orcids":["https://orcid.org/0000-0001-7246-4136"]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"C Viljoen","raw_affiliation_strings":["Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004440549","display_name":"M Black","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"M Black","raw_affiliation_strings":["Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences,\r\nUniversity of Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences,\r\nUniversity of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009435222","display_name":"Graeme Meintjes","orcid":"https://orcid.org/0000-0003-1196-4414","observed_orcids":["https://orcid.org/0000-0003-1196-4414"]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]},{"id":"https://openalex.org/I4405266898","display_name":"Institute of Infectious Disease and Molecular Medicine","ror":"https://ror.org/00900dw59","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274","https://openalex.org/I4405266898"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB","ZA"],"is_corresponding":false,"raw_author_name":"G Meintjes","raw_affiliation_strings":["Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine,\r\nFaculty of Health Sciences, University of Cape Town, South Africa; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; Department of Medicine, Imperial College London, United Kingdom","Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine,\r\nFaculty of Health Sciences, University of Cape Town, South Africa","Department of Medicine, Imperial College London, United Kingdom","Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine,\r\nFaculty of Health Sciences, University of Cape Town, South Africa; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa; Department of Medicine, Imperial College London, United Kingdom","institution_ids":["https://openalex.org/I157614274","https://openalex.org/I4405266898","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine,\r\nFaculty of Health Sciences, University of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274","https://openalex.org/I4405266898"]},{"raw_affiliation_string":"Department of Medicine, Imperial College London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Division of Infectious Diseases and HIV Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":11152,"currency":"ZAR","value_usd":605},"apc_paid":{"value":11152,"currency":"ZAR","value_usd":605},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"3","first_page":"144","last_page":"144"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.2754000127315521,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9539999961853027},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.949999988079071},{"id":"https://openalex.org/keywords/amphotericin-b","display_name":"amphotericin B","score":0.8529999852180481},{"id":"https://openalex.org/keywords/cryptococcal-meningitis","display_name":"cryptococcal meningitis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/phlebitis","display_name":"phlebitis","score":0.7490000128746033},{"id":"https://openalex.org/keywords/central-venous-catheter-related-infection","display_name":"central venous catheter infection","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8935196399688721},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.7039339542388916},{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.664537787437439},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6461015939712524},{"id":"https://openalex.org/C2777238321","wikidata":"https://www.wikidata.org/wiki/Q876887","display_name":"Cellulitis","level":2,"score":0.6131951808929443},{"id":"https://openalex.org/C3019493264","wikidata":"https://www.wikidata.org/wiki/Q1470140","display_name":"Cryptococcal meningitis","level":4,"score":0.4964154362678528},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.42775851488113403},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.384159654378891},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3827608525753021},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2535334825515747},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22370943427085876},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2113649845123291},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.1568560004234314},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.10229271650314331},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.08325323462486267},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4102/sajhivmed.v14i3.70","doi":"https://doi.org/10.4102/sajhivmed.v14i3.70","is_oa":true,"landing_page_url":"https://doi.org/10.4102/sajhivmed.v14i3.70","pdf_url":"https://sajhivmed.org.za/index.php/hivmed/article/download/70/106","source":{"id":"https://openalex.org/S74263619","display_name":"Southern African Journal of HIV Medicine","issn_l":"1608-9693","issn":["1608-9693","2078-6751"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","doyens","jpps-2","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315322","host_organization_name":"AOSIS","host_organization_lineage":["https://openalex.org/P4310315322"],"host_organization_lineage_names":["AOSIS"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern African Journal of HIV Medicine","raw_type":"journal-article"},{"id":"doi:10.7196/sajhivmed.979","doi":"https://doi.org/10.7196/sajhivmed.979","is_oa":true,"landing_page_url":"https://doi.org/10.7196/sajhivmed.979","pdf_url":null,"source":{"id":"https://openalex.org/S74263619","display_name":"Southern African Journal of HIV Medicine","issn_l":"1608-9693","issn":["1608-9693","2078-6751"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","doyens","jpps-2","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315322","host_organization_name":"AOSIS","host_organization_lineage":["https://openalex.org/P4310315322"],"host_organization_lineage_names":["AOSIS"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern African Journal of HIV Medicine","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:16fcf68f8eea4a4a9d11744b6afe4b8c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/16fcf68f8eea4a4a9d11744b6afe4b8c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Southern African Journal of HIV Medicine, Vol 14, Iss 3, Pp 144-146 (2013)","raw_type":"article"},{"id":"pmh:oai:localhost:11427/34826","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11427/34826","pdf_url":null,"source":{"id":"https://openalex.org/S4306402129","display_name":"Open University of Cape Town (University of Cape Town)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I157614274","host_organization_name":"University of Cape Town","host_organization_lineage":["https://openalex.org/I157614274"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Southern African Journal of Hiv Medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4102/sajhivmed.v14i3.70","doi":"https://doi.org/10.4102/sajhivmed.v14i3.70","is_oa":true,"landing_page_url":"https://doi.org/10.4102/sajhivmed.v14i3.70","pdf_url":"https://sajhivmed.org.za/index.php/hivmed/article/download/70/106","source":{"id":"https://openalex.org/S74263619","display_name":"Southern African Journal of HIV Medicine","issn_l":"1608-9693","issn":["1608-9693","2078-6751"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","doyens","jpps-2","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315322","host_organization_name":"AOSIS","host_organization_lineage":["https://openalex.org/P4310315322"],"host_organization_lineage_names":["AOSIS"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern African Journal of HIV Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978446723.pdf","grobid_xml":"https://content.openalex.org/works/W1978446723.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1505577218","https://openalex.org/W2074827635","https://openalex.org/W2088875727","https://openalex.org/W2100485134","https://openalex.org/W2108433768","https://openalex.org/W2124643281","https://openalex.org/W2144543496","https://openalex.org/W2156101960","https://openalex.org/W2164625386","https://openalex.org/W2166356134","https://openalex.org/W2319117370","https://openalex.org/W2320636167"],"related_works":["https://openalex.org/W1979509347","https://openalex.org/W2547738482","https://openalex.org/W2348015445","https://openalex.org/W2145440018","https://openalex.org/W1490120766","https://openalex.org/W1994669492","https://openalex.org/W2274582116","https://openalex.org/W2351629159","https://openalex.org/W2402769752","https://openalex.org/W7098621241"],"abstract_inverted_index":{"Intravenous":[0],"amphotericin":[1,84],"B":[2],"is":[3,24,42],"a":[4],"key":[5],"component":[6],"of":[7,91,99,105],"the":[8,89,100],"antifungal":[9],"therapy":[10],"for":[11],"cryptococcal":[12,69],"meningitis":[13,70],"recommended":[14],"in":[15,31,57,94],"South":[16],"African":[17],"and":[18,37,97],"international":[19],"guidelines.":[20],"Unfortunately,":[21],"its":[22],"use":[23],"associated":[25],"with":[26,68,83],"significant":[27],"toxicity":[28],"including":[29],"deterioration":[30],"renal":[32],"function,":[33],"electrolyte":[34],"disturbance,":[35],"anaemia":[36],"infusion":[38],"reactions.":[39],"Chemical":[40],"phlebitis":[41],"common":[43],"following":[44],"administration":[45],"via":[46],"peripheral":[47],"cannulae.":[48],"This":[49],"can":[50],"be":[51],"complicated":[52],"by":[53],"bacterial":[54,61],"infection,":[55],"resulting":[56],"localised":[58],"cellulitis":[59],"or":[60,79],"sepsis.":[62],"Here":[63],"we":[64],"describe":[65],"two":[66],"patients":[67],"who":[71],"developed":[72],"methicillin-resistant":[73],"Staphylococcus":[74],"aureus":[75],"(MRSA)":[76],"bacteraemia":[77],"during,":[78],"shortly":[80],"after":[81],"treatment":[82,104],"B.":[85],"These":[86],"cases":[87],"illustrate":[88],"dangers":[90],"line-related":[92],"sepsis":[93],"hospitalised":[95],"individuals":[96],"some":[98],"difficulties":[101],"encountered":[102],"during":[103],"this":[106],"condition.":[107]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}