{"id":"https://openalex.org/W1978441935","doi":"https://doi.org/10.2460/ajvr.2002.63.370","title":"Evaluation of a bladder tumor antigen test for the diagnosis of lower urinary tract malignancies in dogs","display_name":"Evaluation of a bladder tumor antigen test for the diagnosis of lower urinary tract malignancies in dogs","publication_year":2002,"publication_date":"2002-03-01","ids":{"openalex":"https://openalex.org/W1978441935","doi":"https://doi.org/10.2460/ajvr.2002.63.370","mag":"1978441935","pmid":"https://pubmed.ncbi.nlm.nih.gov/11926180"},"language":"en","primary_location":{"id":"doi:10.2460/ajvr.2002.63.370","doi":"https://doi.org/10.2460/ajvr.2002.63.370","is_oa":true,"landing_page_url":"https://doi.org/10.2460/ajvr.2002.63.370","pdf_url":"https://avmajournals.avma.org/downloadpdf/journals/ajvr/63/3/ajvr.2002.63.370.pdf","source":{"id":"https://openalex.org/S196975874","display_name":"American Journal of Veterinary Research","issn_l":"0002-9645","issn":["0002-9645","1943-5681"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-2","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4322545313","host_organization_name":"American Veterinary Medical Association","host_organization_lineage":["https://openalex.org/P4322545313"],"host_organization_lineage_names":["American Veterinary Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Veterinary Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://avmajournals.avma.org/downloadpdf/journals/ajvr/63/3/ajvr.2002.63.370.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077835185","display_name":"Jean-Philippe H.G. Billet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jean-Philippe H.G. Billet","raw_affiliation_strings":["Department of Clinical Veterinary Science, Faculty of Medicine, University of Bristol, Langford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Veterinary Science, Faculty of Medicine, University of Bristol, Langford, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034036562","display_name":"Alasdair Hotston Moore","orcid":"https://orcid.org/0000-0001-5404-7283","observed_orcids":["https://orcid.org/0000-0001-5404-7283"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alasdair Hotston Moore","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040002552","display_name":"Peter Holt","orcid":"https://orcid.org/0000-0002-5739-2813","observed_orcids":["https://orcid.org/0000-0002-5739-2813"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter E. Holt","raw_affiliation_strings":["Department of Clinical Veterinary Science , Faculty of Medicine , University of Bristol , Langford House , Langford , Bristol BS40 5DU , UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Veterinary Science , Faculty of Medicine , University of Bristol , Langford House , Langford , Bristol BS40 5DU , UK","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.228,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.89698417,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"63","issue":"3","first_page":"370","last_page":"373"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.5289999842643738},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7170000076293945},{"id":"https://openalex.org/keywords/hematuria","display_name":"hematuria","score":0.8659999966621399},{"id":"https://openalex.org/keywords/urine-sample-storage","display_name":"urine sample storage","score":0.5199999809265137},{"id":"https://openalex.org/keywords/urine-ph","display_name":"urine pH","score":0.7480000257492065},{"id":"https://openalex.org/keywords/urine-specific-gravity","display_name":"urine specific gravity","score":0.9279999732971191},{"id":"https://openalex.org/keywords/intra-observer-variability","display_name":"intraobserver variability","score":0.621999979019165}],"concepts":[{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.8391692042350769},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7940804362297058},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.7757035493850708},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5640295147895813},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.5194898843765259},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.5120778679847717},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.5077129602432251},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4149625301361084},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41434958577156067},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38115525245666504},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3621087670326233},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3306221067905426},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000951","descriptor_name":"Antigens, Neoplasm","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006417","descriptor_name":"Hematuria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007841","descriptor_name":"Latex Fixation Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007841","descriptor_name":"Latex Fixation Tests","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013046","descriptor_name":"Specific Gravity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D014571","descriptor_name":"Urologic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014571","descriptor_name":"Urologic Neoplasms","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D014571","descriptor_name":"Urologic Neoplasms","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D015588","descriptor_name":"Observer Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2460/ajvr.2002.63.370","doi":"https://doi.org/10.2460/ajvr.2002.63.370","is_oa":true,"landing_page_url":"https://doi.org/10.2460/ajvr.2002.63.370","pdf_url":"https://avmajournals.avma.org/downloadpdf/journals/ajvr/63/3/ajvr.2002.63.370.pdf","source":{"id":"https://openalex.org/S196975874","display_name":"American Journal of Veterinary Research","issn_l":"0002-9645","issn":["0002-9645","1943-5681"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-2","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4322545313","host_organization_name":"American Veterinary Medical Association","host_organization_lineage":["https://openalex.org/P4322545313"],"host_organization_lineage_names":["American Veterinary Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Veterinary Research","raw_type":"journal-article"},{"id":"pmid:11926180","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11926180","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of veterinary research","raw_type":"Evaluation Study"}],"best_oa_location":{"id":"doi:10.2460/ajvr.2002.63.370","doi":"https://doi.org/10.2460/ajvr.2002.63.370","is_oa":true,"landing_page_url":"https://doi.org/10.2460/ajvr.2002.63.370","pdf_url":"https://avmajournals.avma.org/downloadpdf/journals/ajvr/63/3/ajvr.2002.63.370.pdf","source":{"id":"https://openalex.org/S196975874","display_name":"American Journal of Veterinary Research","issn_l":"0002-9645","issn":["0002-9645","1943-5681"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-2","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4322545313","host_organization_name":"American Veterinary Medical Association","host_organization_lineage":["https://openalex.org/P4322545313"],"host_organization_lineage_names":["American Veterinary Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Veterinary Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978441935.pdf","grobid_xml":"https://content.openalex.org/works/W1978441935.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W22723071","https://openalex.org/W106398603","https://openalex.org/W178785134","https://openalex.org/W1965099011","https://openalex.org/W1995949483","https://openalex.org/W2006091738","https://openalex.org/W2031279090","https://openalex.org/W2046638859","https://openalex.org/W2054734418","https://openalex.org/W2057449393","https://openalex.org/W2095194089","https://openalex.org/W2125908690","https://openalex.org/W2140633541","https://openalex.org/W2167072086","https://openalex.org/W2294652635","https://openalex.org/W2338139126","https://openalex.org/W2414601739","https://openalex.org/W2778146192","https://openalex.org/W4390363786"],"related_works":["https://openalex.org/W2129967741","https://openalex.org/W4255583615","https://openalex.org/W2031279090","https://openalex.org/W4405035128","https://openalex.org/W2006091738","https://openalex.org/W1495553874","https://openalex.org/W7120858092","https://openalex.org/W1965099011","https://openalex.org/W2912682140","https://openalex.org/W1558455145"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"the":[3,191,229],"use":[4],"of":[5,14,62,69,76,134,138,190,231],"a":[6,224],"human":[7],"bladder":[8,179],"tumor":[9,180],"antigen":[10,181],"test":[11,80,151,182],"for":[12,95,112,185,205,228],"diagnosis":[13],"lower":[15,38,99,192,214,232],"urinary":[16,28,39,45,100,121,193,198,215,233],"tract":[17,29,40,46,101,122,194,199,216,234],"malignancies":[18,189,235],"in":[19,236],"dogs.":[20,237],"SAMPLE":[21],"POPULATION:":[22],"Urine":[23],"samples":[24,78],"from":[25,35,103,117,142,195,210],"dogs":[26,36,97,104,114,118,125,143,187,196,207,211],"without":[27,105,144,197],"abnormalities":[30],"(n":[31],"=":[32],"18)":[33],"and":[34,56,65,71,74,88,92],"with":[37,98,115,119,126,188,208,212],"neoplasia":[41,102,116,209],"(20)":[42],"or":[43,162,165],"nonmalignant":[44,120],"disease":[47],"(16).":[48],"PROCEDURE:":[49],"Test":[50,86],"results":[51,81,128],"were":[52,82,90,129],"compared":[53],"among":[54,57],"groups":[55],"3":[58],"observers.":[59],"The":[60],"effects":[61],"urine":[63,77,141,158],"pH":[64],"specific":[66,160,204],"gravity,":[67,161],"degree":[68,133],"hematuria,":[70],"storage":[72,163],"temperature":[73,166],"time":[75,164],"on":[79,150,171],"also":[83],"assessed.":[84],"RESULTS:":[85],"sensitivity":[87],"specificity":[89,108],"90":[91],"94.4%,":[93],"respectively,":[94],"differentiating":[96,113,186,206],"abnormalities.":[106,217],"However,":[107,136],"decreased":[109],"to":[110,140],"35%":[111],"disease.":[123],"In":[124],"neoplasia,":[127],"significantly":[130],"affected":[131],"by":[132],"hematuria.":[135],"addition":[137],"blood":[139],"hematuria":[145],"had":[146,167],"no":[147,168],"significant":[148,169],"effect":[149,170],"results.":[152,172],"Although":[153,177],"intraobserver":[154],"variation":[155],"was":[156,183,202],"significant,":[157],"pH,":[159],"CONCLUSIONS":[173],"AND":[174],"CLINICAL":[175],"RELEVANCE:":[176],"this":[178],"sensitive":[184],"disease,":[200],"it":[201],"not":[203],"other":[213],"It":[218],"cannot,":[219],"therefore,":[220],"be":[221],"recommended":[222],"as":[223],"definitive":[225],"diagnostic":[226],"aid":[227],"detection":[230]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}