{"id":"https://openalex.org/W1978402873","doi":"https://doi.org/10.1101/gad.177774.111","title":"Intronic miR-26b controls neuronal differentiation by repressing its host transcript,ctdsp2","display_name":"Intronic miR-26b controls neuronal differentiation by repressing its host transcript,ctdsp2","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1978402873","doi":"https://doi.org/10.1101/gad.177774.111","mag":"1978402873","pmid":"https://pubmed.ncbi.nlm.nih.gov/22215807","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3258962"},"language":"en","primary_location":{"id":"doi:10.1101/gad.177774.111","doi":"https://doi.org/10.1101/gad.177774.111","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.177774.111","pdf_url":"http://genesdev.cshlp.org/content/26/1/25.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://genesdev.cshlp.org/content/26/1/25.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035843035","display_name":"Holger Dill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Holger Dill","raw_affiliation_strings":["Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, W\u00fcrzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032304407","display_name":"Bastian Linder","orcid":"https://orcid.org/0000-0003-1203-3136","observed_orcids":["https://orcid.org/0000-0003-1203-3136"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["CH","DE"],"is_corresponding":false,"raw_author_name":"Bastian Linder","raw_affiliation_strings":["Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","Department of Biochemistry, Theodor Boveri-Institute,","Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]},{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute,","institution_ids":[]},{"raw_affiliation_string":"Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037946418","display_name":"Alexander G. J. Fehr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["CH","DE"],"is_corresponding":false,"raw_author_name":"Alexander Fehr","raw_affiliation_strings":["Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","Department of Biochemistry, Theodor Boveri-Institute,","Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]},{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute,","institution_ids":[]},{"raw_affiliation_string":"Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012562828","display_name":"Utz Fischer","orcid":"https://orcid.org/0000-0002-1465-6591","observed_orcids":["https://orcid.org/0000-0002-1465-6591"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["CH","DE"],"is_corresponding":true,"raw_author_name":"Utz Fischer","raw_affiliation_strings":["Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","Department of Biochemistry, Theodor Boveri-Institute,","Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute, University of W\u00fcrzburg, D-97074 W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]},{"raw_affiliation_string":"Department of Biochemistry, Theodor Boveri-Institute,","institution_ids":[]},{"raw_affiliation_string":"Institute for Veterinary Pathology, Vetsiusse fac-ulty, University of Zu \u00a8rich, Winterthurerstrasse 268, CH-8057 Zu \u00a8rich, Switzerland","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"University of Wu \u00a8rzburg, D-97074 Wu \u00a8rzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012562828"],"corresponding_institution_ids":["https://openalex.org/I202697423","https://openalex.org/I25974101"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":132,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"1","first_page":"25","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9053000211715698,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.07750000059604645,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-26b","display_name":"miR-26b","score":0.9980000257492065},{"id":"https://openalex.org/keywords/microrna-host-gene","display_name":"microRNA host gene","score":0.4359999895095825},{"id":"https://openalex.org/keywords/intronic-microrna","display_name":"intronic microRNA","score":0.7590000033378601},{"id":"https://openalex.org/keywords/rest-nrsf","display_name":"REST/NRSF","score":0.6570000052452087},{"id":"https://openalex.org/keywords/neural-stem-cell-differentiation","display_name":"neural stem cell differentiation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/neuronal-differentiation","display_name":"neuronal differentiation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.925000011920929},{"id":"https://openalex.org/keywords/negative-feedback-loop","display_name":"negative feedback loop","score":0.800000011920929},{"id":"https://openalex.org/keywords/microrna-biogenesis","display_name":"microRNA biogenesis","score":0.8029999732971191},{"id":"https://openalex.org/keywords/rna-polymerase-ii-c-terminal-domain","display_name":"RNA polymerase II C-terminal domain","score":0.843999981880188}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9091572761535645},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.8170962333679199},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.6633403897285461},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.6329085230827332},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5663933157920837},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.5241339802742004},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.47745826840400696},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.46828457713127136},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4482734203338623},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.4387708902359009},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41979312896728516},{"id":"https://openalex.org/C67585878","wikidata":"https://www.wikidata.org/wiki/Q7243183","display_name":"Primary transcript","level":5,"score":0.4130687713623047},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4027935266494751},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.3795461356639862},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36418554186820984},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.19043231010437012},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.10049444437026978},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010749","descriptor_name":"Phosphoprotein Phosphatases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1101/gad.177774.111","doi":"https://doi.org/10.1101/gad.177774.111","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.177774.111","pdf_url":"http://genesdev.cshlp.org/content/26/1/25.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3258962","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3258962","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes Dev","raw_type":"Text"},{"id":"pmid:22215807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22215807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & development","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1101/gad.177774.111","doi":"https://doi.org/10.1101/gad.177774.111","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gad.177774.111","pdf_url":"http://genesdev.cshlp.org/content/26/1/25.full.pdf","source":{"id":"https://openalex.org/S168778273","display_name":"Genes & Development","issn_l":"0890-9369","issn":["0890-9369","1549-5477"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes & Development","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978402873.pdf","grobid_xml":"https://content.openalex.org/works/W1978402873.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1970829776","https://openalex.org/W1974950833","https://openalex.org/W1977130958","https://openalex.org/W1978337436","https://openalex.org/W1981186391","https://openalex.org/W1995865634","https://openalex.org/W1997932830","https://openalex.org/W1999874171","https://openalex.org/W2017270642","https://openalex.org/W2027815400","https://openalex.org/W2036475318","https://openalex.org/W2039141906","https://openalex.org/W2040190285","https://openalex.org/W2045342567","https://openalex.org/W2049907435","https://openalex.org/W2050869737","https://openalex.org/W2059805004","https://openalex.org/W2071925802","https://openalex.org/W2091811407","https://openalex.org/W2094253263","https://openalex.org/W2097751554","https://openalex.org/W2104806799","https://openalex.org/W2107444074","https://openalex.org/W2114870653","https://openalex.org/W2128464557","https://openalex.org/W2136295536","https://openalex.org/W2142718844","https://openalex.org/W2151911276","https://openalex.org/W2159807040","https://openalex.org/W2160102037","https://openalex.org/W2161272397","https://openalex.org/W2164598261","https://openalex.org/W2171230529","https://openalex.org/W4297820284","https://openalex.org/W7140261974"],"related_works":["https://openalex.org/W1993451395","https://openalex.org/W3160249752","https://openalex.org/W7113810484","https://openalex.org/W6927306644","https://openalex.org/W3152618497","https://openalex.org/W7113112552","https://openalex.org/W6964706635","https://openalex.org/W2118757935","https://openalex.org/W2054661497","https://openalex.org/W2040190285"],"abstract_inverted_index":{"Differentiation":[0],"of":[1,11,31,57,83,93,117],"neural":[2],"stem":[3],"cells":[4],"(NSCs)":[5],"to":[6],"neurons":[7],"requires":[8],"the":[9,15,94,113],"activation":[10],"genes":[12,58],"controlled":[13,59],"by":[14,60],"repressor":[16],"element":[17],"1":[18],"(RE1)":[19],"silencing":[20],"transcription":[21],"factor":[22,25],"(REST)/neuron-restrictive":[23],"silencer":[24],"(NRSF)":[26],"protein":[27,128],"complex.":[28],"Important":[29],"components":[30],"REST/NRSF":[32],"are":[33],"phosphatases":[34,42],"(termed":[35],"RNA":[36,46],"polymerase":[37,47],"II":[38,48],"C-terminal":[39],"domain":[40],"small":[41],"[CTDSPs])":[43],"that":[44,78,87],"inhibit":[45],"and":[49,130],"suppress":[50],"neuronal":[51,134],"gene":[52],"expression":[53,129],"in":[54,90,105,137],"NSCs.":[55],"Activation":[56],"CTDSPs":[61],"is":[62,69,71,80,88,103,110,120,131],"required":[63,132],"for":[64,133],"neurogenesis,":[65,123],"but":[66],"how":[67],"this":[68],"achieved":[70],"not":[72],"fully":[73],"understood.":[74],"Here":[75],"we":[76],"show":[77],"ctdsp2":[79,95],"a":[81,85],"target":[82],"miR-26b,":[84],"microRNA":[86],"encoded":[89],"an":[91],"intron":[92],"primary":[96],"transcript.":[97],"This":[98],"intrinsic":[99],"negative":[100],"feedback":[101],"loop":[102],"inactive":[104],"NSCs":[106],"because":[107],"miR-26b":[108,119],"biogenesis":[109],"inhibited":[111],"at":[112],"precursor":[114],"level.":[115],"Generation":[116],"mature":[118],"activated":[121],"during":[122],"where":[124],"it":[125],"suppresses":[126],"Ctdsp2":[127],"cell":[135],"differentiation":[136],"vivo.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":16},{"year":2015,"cited_by_count":21},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}