{"id":"https://openalex.org/W1978384276","doi":"https://doi.org/10.1074/jbc.m003402200","title":"FER Kinase Activation of Stat3 Is Determined by the N-terminal Sequence","display_name":"FER Kinase Activation of Stat3 Is Determined by the N-terminal Sequence","publication_year":2000,"publication_date":"2000-09-01","ids":{"openalex":"https://openalex.org/W1978384276","doi":"https://doi.org/10.1074/jbc.m003402200","mag":"1978384276","pmid":"https://pubmed.ncbi.nlm.nih.gov/10878010"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m003402200","doi":"https://doi.org/10.1074/jbc.m003402200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m003402200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m003402200","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007708970","display_name":"Smadar Priel-Halachmi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Smadar Priel-Halachmi","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026712484","display_name":"Israel Ben\u2010Dor","orcid":"https://orcid.org/0000-0002-9745-5196","observed_orcids":["https://orcid.org/0000-0002-9745-5196"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Israel Ben-Dor","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024915428","display_name":"Sally Shpungin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Sally Shpungin","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050527834","display_name":"Tamar Tennenbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Tamar Tennenbaum","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083822218","display_name":"Hana Molavani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Hana Molavani","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007462633","display_name":"Michal Bachrach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Michal Bachrach","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111839696","display_name":"Samuel Salzberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Samuel Salzberg","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012748714","display_name":"Uri Nir","orcid":"https://orcid.org/0000-0002-5867-2251","observed_orcids":["https://orcid.org/0000-0002-5867-2251"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Uri Nir","raw_affiliation_strings":["Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]},{"raw_affiliation_string":"From the Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel","institution_ids":["https://openalex.org/I13955877"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5012748714"],"corresponding_institution_ids":["https://openalex.org/I13955877"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.1309,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.75714286,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"275","issue":"37","first_page":"28902","last_page":"28910"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fer-kinase","display_name":"Fer kinase","score":0.7310000061988831},{"id":"https://openalex.org/keywords/stat3","display_name":"STAT3","score":0.6060000061988831},{"id":"https://openalex.org/keywords/tyrosine-phosphorylation","display_name":"tyrosine phosphorylation","score":0.8489999771118164},{"id":"https://openalex.org/keywords/n-terminal-sequence","display_name":"N-terminal sequence","score":0.8059999942779541},{"id":"https://openalex.org/keywords/tyrosine-kinase-activation","display_name":"tyrosine kinase activation","score":0.6399999856948853},{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"subcellular localization","score":0.8579999804496765},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.828000009059906},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.656000018119812},{"id":"https://openalex.org/keywords/stat2","display_name":"STAT2","score":0.968999981880188}],"concepts":[{"id":"https://openalex.org/C71829478","wikidata":"https://www.wikidata.org/wiki/Q901305","display_name":"Immunoprecipitation","level":3,"score":0.8369631767272949},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.7796897888183594},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.6631897687911987},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.6569961905479431},{"id":"https://openalex.org/C2777553839","wikidata":"https://www.wikidata.org/wiki/Q14330986","display_name":"Tyrosine phosphorylation","level":3,"score":0.643500566482544},{"id":"https://openalex.org/C197153747","wikidata":"https://www.wikidata.org/wiki/Q24780316","display_name":"SH2 domain","level":4,"score":0.5793104767799377},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5713990330696106},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5508117079734802},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.5051310658454895},{"id":"https://openalex.org/C2776879804","wikidata":"https://www.wikidata.org/wiki/Q7630919","display_name":"Subcellular localization","level":3,"score":0.4891689121723175},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4844786822795868},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.40677914023399353},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.3968963027000427},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2722334861755371},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07273808121681213}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014443","descriptor_name":"Tyrosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016475","descriptor_name":"3T3 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019556","descriptor_name":"COS Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050796","descriptor_name":"STAT3 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.m003402200","doi":"https://doi.org/10.1074/jbc.m003402200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m003402200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:10878010","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10878010","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m003402200","doi":"https://doi.org/10.1074/jbc.m003402200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m003402200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W49941713","https://openalex.org/W159302622","https://openalex.org/W168754456","https://openalex.org/W1483520515","https://openalex.org/W1550156431","https://openalex.org/W1908892780","https://openalex.org/W1943347383","https://openalex.org/W1959486232","https://openalex.org/W1968572778","https://openalex.org/W1974136298","https://openalex.org/W2001306989","https://openalex.org/W2007058107","https://openalex.org/W2009952247","https://openalex.org/W2016730049","https://openalex.org/W2029312116","https://openalex.org/W2032099089","https://openalex.org/W2035134361","https://openalex.org/W2044618871","https://openalex.org/W2071872700","https://openalex.org/W2074356752","https://openalex.org/W2076600290","https://openalex.org/W2078362278","https://openalex.org/W2081003617","https://openalex.org/W2083405476","https://openalex.org/W2083802827","https://openalex.org/W2086715846","https://openalex.org/W2089388428","https://openalex.org/W2096503154","https://openalex.org/W2101283727","https://openalex.org/W2105512558","https://openalex.org/W2108481832","https://openalex.org/W2108651703","https://openalex.org/W2114375471","https://openalex.org/W2120019133","https://openalex.org/W2132888121","https://openalex.org/W2138807703","https://openalex.org/W2140506935","https://openalex.org/W2144935474","https://openalex.org/W2147550224","https://openalex.org/W2154148872","https://openalex.org/W2156239323","https://openalex.org/W2163046152","https://openalex.org/W2163951902","https://openalex.org/W2166543499","https://openalex.org/W2173560213","https://openalex.org/W2322086909","https://openalex.org/W2410414924","https://openalex.org/W2413457152","https://openalex.org/W2418063160","https://openalex.org/W2496865180"],"related_works":["https://openalex.org/W1976449189","https://openalex.org/W2108651703","https://openalex.org/W7097665502","https://openalex.org/W2043012027","https://openalex.org/W2030865745","https://openalex.org/W2045041761","https://openalex.org/W2160770127","https://openalex.org/W7097761138","https://openalex.org/W1968572778","https://openalex.org/W2009952247"],"abstract_inverted_index":{"p94(fer)":[0,57,75,104,156,177],"and":[1,11,37,64,103,178,189],"p51(ferT)":[2,121,146,164,179],"are":[3,90],"two":[4,28,115],"tyrosine":[5,31,62],"kinases":[6],"that":[7,56],"share":[8],"identical":[9],"SH2":[10],"kinase":[12],"domains":[13],"but":[14,68,129,165],"differ":[15],"in":[16,38,81,117],"their":[17,33,182,193],"N-terminal":[18,143,153,174],"regions.":[19],"To":[20],"further":[21],"explore":[22],"the":[23,61,82,97,111,125,132,139,152,160,172],"cellular":[24,195],"functions":[25],"of":[26,66,70,87,99,113,127,134,145,155,163,176,187],"these":[27,114],"highly":[29],"related":[30],"kinases,":[32],"subcellular":[34,161],"distribution":[35],"profiles":[36],"vivo":[39],"phosphorylation":[40,63,98,126,133,186],"activity":[41,78],"were":[42],"followed":[43],"using":[44],"double":[45],"immunofluorescence":[46],"assay.":[47],"When":[48],"combined":[49],"with":[50,106,147],"immunoprecipitation":[51],"analysis,":[52],"this":[53,77],"assay":[54],"showed":[55],"can":[58,180],"lead":[59,95],"to":[60,96,131,168,184],"activation":[65],"Stat3":[67,102,128,188],"not":[69,123,158],"Stat1":[71],"or":[72],"Stat2.":[73],"Native":[74],"exerted":[76],"when":[79],"residing":[80],"cytoplasm.":[83],"However,":[84],"modified":[85],"forms":[86],"p94(fer),":[88,120],"which":[89],"constitutively":[91],"nuclear,":[92],"could":[93],"also":[94],"Stat3.":[100,170],"Endogenous":[101],"co-immunoprecipitated":[105],"each":[107],"other,":[108],"thus":[109],"proving":[110],"interaction":[112],"proteins":[116],"vivo.":[118],"Unlike":[119],"did":[122,157],"induce":[124,185],"led":[130],"other":[135],"nuclear":[136],"proteins.":[137],"Replacing":[138],"unique":[140],"43-amino":[141],"acid-long":[142],"tail":[144,154],"a":[148],"parallel":[149],"segment":[150],"from":[151],"change":[159],"localization":[162],"enabled":[166],"it":[167],"activate":[169],"Thus":[171],"different":[173,194],"sequences":[175],"affect":[181],"ability":[183],"most":[190],"probably":[191],"direct":[192],"functions.":[196]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}