{"id":"https://openalex.org/W1978353146","doi":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","title":"Antioxidant vitamin supplementation in Crohn's disease decreases oxidative stress a randomized controlled trial","display_name":"Antioxidant vitamin supplementation in Crohn's disease decreases oxidative stress a randomized controlled trial","publication_year":2003,"publication_date":"2003-02-01","ids":{"openalex":"https://openalex.org/W1978353146","doi":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","mag":"1978353146","pmid":"https://pubmed.ncbi.nlm.nih.gov/12591053"},"language":"en","primary_location":{"id":"doi:10.1111/j.1572-0241.2003.07226.x","doi":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113614396","display_name":"Elaheh Aghdassi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I2801845744","display_name":"Toronto General Hospital","ror":"https://ror.org/026pg9j08","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Elaheh Aghdassi","raw_affiliation_strings":["Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073975475","display_name":"Barbara E. Wendland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I2801845744","display_name":"Toronto General Hospital","ror":"https://ror.org/026pg9j08","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Barbara E. Wendland","raw_affiliation_strings":["Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076996656","display_name":"A. Hillary Steinhart","orcid":"https://orcid.org/0000-0001-7794-6150","observed_orcids":["https://orcid.org/0000-0001-7794-6150","https://orcid.org/0009-0000-4781-9601"]},"institutions":[{"id":"https://openalex.org/I1324220072","display_name":"Mount Sinai Hospital","ror":"https://ror.org/01zkyz108","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I1324220072"]},{"id":"https://openalex.org/I4210101641","display_name":"Mount Sinai Hospital","ror":"https://ror.org/019jr0130","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210101641","https://openalex.org/I4210149743"]},{"id":"https://openalex.org/I4210102044","display_name":"Mount Sinai Hospital","ror":"https://ror.org/01h9y0t02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4210102044"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.Hillary Steinhart","raw_affiliation_strings":["Division of Gastroenterology, Mount Sinai Hospital; USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Mount Sinai Hospital; USA","institution_ids":["https://openalex.org/I1324220072","https://openalex.org/I4210101641","https://openalex.org/I4210102044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109042217","display_name":"Stephen L. Wolman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I2801845744","display_name":"Toronto General Hospital","ror":"https://ror.org/026pg9j08","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Stephen L. Wolman","raw_affiliation_strings":["Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110881573","display_name":"Khursheed N. Jeejeebhoy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1297363086","display_name":"St. Michael's Hospital","ror":"https://ror.org/04skqfp25","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1297363086","https://openalex.org/I4399598460"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Khursheed Jeejeebhoy","raw_affiliation_strings":["Division of Gastroenterology, St. Michael Hospital, University of Toronto, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, St. Michael Hospital, University of Toronto, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1297363086","https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065541229","display_name":"Johane P. Allard","orcid":"https://orcid.org/0000-0002-8956-7059","observed_orcids":["https://orcid.org/0000-0002-8956-7059"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I2801845744","display_name":"Toronto General Hospital","ror":"https://ror.org/026pg9j08","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Johane P. Allard","raw_affiliation_strings":["Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology and Nutrition Research, Department of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":7.2086,"has_fulltext":false,"cited_by_count":141,"citation_normalized_percentile":{"value":0.97158786,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"98","issue":"2","first_page":"348","last_page":"353"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.46560001373291016,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8849999904632568},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.968999981880188},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9959999918937683},{"id":"https://openalex.org/keywords/alpha-tocopherol","display_name":"alpha-tocopherol","score":0.8519999980926514},{"id":"https://openalex.org/keywords/lipid-hydroperoxides","display_name":"lipid hydroperoxides","score":0.8500000238418579},{"id":"https://openalex.org/keywords/f2-isoprostanes","display_name":"F2-isoprostanes","score":0.9459999799728394},{"id":"https://openalex.org/keywords/alpha-1-acid-glycoprotein","display_name":"alpha-1-acid glycoprotein","score":0.8500000238418579},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.7870000004768372},{"id":"https://openalex.org/keywords/maintenance-therapy","display_name":"maintenance therapy","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8794976472854614},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.7643775939941406},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7606848478317261},{"id":"https://openalex.org/C2777551382","wikidata":"https://www.wikidata.org/wiki/Q141180","display_name":"Vitamin E","level":3,"score":0.689127504825592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.656153678894043},{"id":"https://openalex.org/C2780022331","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Vitamin C","level":2,"score":0.6221253275871277},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.6052299737930298},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5211320519447327},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5073067545890808},{"id":"https://openalex.org/C2779280984","wikidata":"https://www.wikidata.org/wiki/Q1472","display_name":"Crohn's disease","level":3,"score":0.4940791428089142},{"id":"https://openalex.org/C2780340399","wikidata":"https://www.wikidata.org/wiki/Q4198767","display_name":"Isoprostane","level":4,"score":0.4783477485179901},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3288886547088623},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.30201661586761475},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2728531062602997},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14135664701461792},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07577157020568848},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009961","descriptor_name":"Orosomucoid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1572-0241.2003.07226.x","doi":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2003.07226.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"doi:10.1016/s0002-9270(02)05894-x","doi":"https://doi.org/10.1016/s0002-9270(02)05894-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9270(02)05894-x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:12591053","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12591053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W71395560","https://openalex.org/W73457141","https://openalex.org/W134031355","https://openalex.org/W145879492","https://openalex.org/W1543776771","https://openalex.org/W1595582953","https://openalex.org/W1761355724","https://openalex.org/W1843577504","https://openalex.org/W1848314313","https://openalex.org/W1861709718","https://openalex.org/W1971288600","https://openalex.org/W1972153352","https://openalex.org/W1972987064","https://openalex.org/W1987522739","https://openalex.org/W1994175131","https://openalex.org/W2000181213","https://openalex.org/W2003471941","https://openalex.org/W2015747169","https://openalex.org/W2016098250","https://openalex.org/W2024016832","https://openalex.org/W2025653612","https://openalex.org/W2027416526","https://openalex.org/W2029195724","https://openalex.org/W2036682827","https://openalex.org/W2042421205","https://openalex.org/W2046513049","https://openalex.org/W2049785542","https://openalex.org/W2069050448","https://openalex.org/W2072796605","https://openalex.org/W2081754558","https://openalex.org/W2087270394","https://openalex.org/W2089830686","https://openalex.org/W2092305480","https://openalex.org/W2109977819","https://openalex.org/W2116984449","https://openalex.org/W2124072462","https://openalex.org/W2129463932","https://openalex.org/W2140082235","https://openalex.org/W2142469544","https://openalex.org/W2153857454","https://openalex.org/W2165347895","https://openalex.org/W2171265231","https://openalex.org/W2322802533","https://openalex.org/W2323652843","https://openalex.org/W2404854108","https://openalex.org/W2405501362","https://openalex.org/W2768323601","https://openalex.org/W3149527659","https://openalex.org/W4214589643","https://openalex.org/W4293103701"],"related_works":["https://openalex.org/W7133041027","https://openalex.org/W2039987491","https://openalex.org/W1843577504","https://openalex.org/W2019241557","https://openalex.org/W1980270812","https://openalex.org/W2541803109","https://openalex.org/W2320958669","https://openalex.org/W2014540972","https://openalex.org/W2154020258","https://openalex.org/W2091263675"],"abstract_inverted_index":{"OBJECTIVE:":[0],"We":[1],"showed":[2],"previously":[3],"that":[4,162],"patients":[5,43,163],"with":[6,19,72,164],"Crohn's":[7],"disease":[8,29],"(CD)":[9],"had":[10],"increased":[11,130,176],"oxidative":[12,51,135,158],"stress":[13,88,136],"and":[14,30,77,93,99,105,119,128,131,149,174],"lower":[15],"antioxidant":[16,47,179],"vitamins":[17,73],"compared":[18],"healthy":[20],"controls.":[21],"This":[22,54,160],"is":[23,55],"despite":[24],"inactive":[25,165],"or":[26,81,166],"mildly":[27,167],"active":[28,168],"maintenance":[31],"therapy.":[32],"The":[33],"aim":[34],"of":[35,46,134],"this":[36,145],"study":[37],"was":[38,101,111],"to":[39],"evaluate":[40],"in":[41,153,157,178],"these":[42],"the":[44],"effects":[45],"vitamin":[48,126,147],"supplementation":[49,151],"on":[50],"stress.":[52,159],"METHODS:":[53],"a":[56,154],"randomized":[57],"controlled":[58],"trial":[59],"where":[60],"stable":[61],"but":[62],"oxidatively":[63,172],"stressed":[64,173],"CD":[65,116,169],"subjects":[66],"(n":[67],"=":[68],"57)":[69],"were":[70],"supplemented":[71],"E":[74,148],"(800":[75],"IU)":[76],"C":[78,127,150],"(1000":[79],"mg)":[80],"their":[82],"placebo":[83],"for":[84],"4":[85,107],"wk.":[86,108],"Oxidative":[87],"measured":[89],"by":[90,114],"breath":[91],"pentane":[92],"ethane":[94],"output,":[95],"plasma":[96,120,125],"lipid":[97],"peroxides,":[98],"F2-isoprostane":[100],"assessed":[102],"at":[103,106],"baseline":[104],"Disease":[109,139],"activity":[110,117,140],"also":[112],"monitored":[113],"measuring":[115],"index":[118],"orosomucoid.":[121],"RESULTS:":[122],"During":[123],"supplementation,":[124],"alpha-tocopherol":[129],"all":[132],"indices":[133],"decreased":[137],"significantly.":[138],"remained":[141],"stable.":[142],"CONCLUSIONS:":[143],"In":[144],"population,":[146],"resulted":[152],"significant":[155],"reduction":[156],"suggests":[161],"can":[170],"be":[171],"have":[175],"requirement":[177],"vitamins.":[180]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}