{"id":"https://openalex.org/W1978333303","doi":"https://doi.org/10.1073/pnas.1018064108","title":"Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells","display_name":"Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells","publication_year":2011,"publication_date":"2011-01-21","ids":{"openalex":"https://openalex.org/W1978333303","doi":"https://doi.org/10.1073/pnas.1018064108","mag":"1978333303","pmid":"https://pubmed.ncbi.nlm.nih.gov/21257905","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038774"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.1018064108","doi":"https://doi.org/10.1073/pnas.1018064108","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1018064108","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038774","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034350503","display_name":"Sai P. Thankamony","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sai P. Thankamony","raw_affiliation_strings":["Departments of aDermatology and","Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and","Departments of aDermatology and; Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of aDermatology and","institution_ids":[]},{"raw_affiliation_string":"Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Departments of aDermatology and; Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103273503","display_name":"Robert Sackstein","orcid":"https://orcid.org/0000-0003-1757-891X","observed_orcids":["https://orcid.org/0000-0003-1757-891X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Sackstein","raw_affiliation_strings":["Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115","Departments of aDermatology and","Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and","Medicine, Brigham and Women's Hospital, Boston, MA 02115;","Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; Departments of aDermatology and; Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and; Medicine, Brigham and Women's Hospital, Boston, MA 02115;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115","institution_ids":["https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Departments of aDermatology and","institution_ids":[]},{"raw_affiliation_string":"Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Medicine, Brigham and Women's Hospital, Boston, MA 02115;","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; Departments of aDermatology and; Harvard Skin Disease Research Center, Harvard Medical School, Boston, MA 02115; and; Medicine, Brigham and Women's Hospital, Boston, MA 02115;","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210161994"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.3326,"has_fulltext":false,"cited_by_count":101,"citation_normalized_percentile":{"value":0.98276451,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"108","issue":"6","first_page":"2258","last_page":"2263"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/e-selectin-ligand","display_name":"E-selectin ligand","score":0.875},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/transendothelial-migration","display_name":"transendothelial migration","score":0.9750000238418579},{"id":"https://openalex.org/keywords/vcam-1","display_name":"VCAM-1","score":0.8859999775886536},{"id":"https://openalex.org/keywords/osteotropism","display_name":"osteotropism","score":0.9089999794960022}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7611137628555298},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6914399266242981},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.575048565864563},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.5508461594581604},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.4883241355419159},{"id":"https://openalex.org/C2779717556","wikidata":"https://www.wikidata.org/wiki/Q15325735","display_name":"RAC1","level":3,"score":0.48530977964401245},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44879311323165894},{"id":"https://openalex.org/C155619193","wikidata":"https://www.wikidata.org/wiki/Q415915","display_name":"Selectin","level":3,"score":0.4452642798423767},{"id":"https://openalex.org/C54166955","wikidata":"https://www.wikidata.org/wiki/Q658145","display_name":"Chemotaxis","level":3,"score":0.43789908289909363},{"id":"https://openalex.org/C2780932548","wikidata":"https://www.wikidata.org/wiki/Q1056532","display_name":"CD44","level":3,"score":0.4357479214668274},{"id":"https://openalex.org/C12823836","wikidata":"https://www.wikidata.org/wiki/Q24720618","display_name":"Chemokine receptor","level":4,"score":0.4288766086101532},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.42068976163864136},{"id":"https://openalex.org/C129470790","wikidata":"https://www.wikidata.org/wiki/Q415718","display_name":"CXCR4","level":4,"score":0.4127904176712036},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3683784008026123},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.34904545545578003},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.3465411067008972},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.33447688817977905},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.26357072591781616},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2353377640247345},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07635977864265442}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018920","descriptor_name":"Coculture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018960","descriptor_name":"Hyaluronan Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019010","descriptor_name":"Vascular Cell Adhesion Molecule-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019040","descriptor_name":"E-Selectin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019718","descriptor_name":"Receptors, CXCR4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020830","descriptor_name":"rac1 GTP-Binding Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D039041","descriptor_name":"Integrin alpha4beta1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1073/pnas.1018064108","doi":"https://doi.org/10.1073/pnas.1018064108","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.1018064108","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2158169","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038774","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3038774","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038774","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:21257905","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21257905","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"mag:2764855112","doi":null,"is_oa":false,"landing_page_url":"https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201102266896959026","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2158169","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038774","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1075872708","display_name":"Optimizing Osteotropism of Human Mesenchymal Stem Cells","funder_award_id":"R01HL073714","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1549021791","display_name":"Molecular Analysis of CD44 on Colon Cancer Cells","funder_award_id":"R01CA121335","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1490812749","https://openalex.org/W1593480505","https://openalex.org/W1967217261","https://openalex.org/W1980772641","https://openalex.org/W1984033056","https://openalex.org/W1987081782","https://openalex.org/W2008449035","https://openalex.org/W2011653132","https://openalex.org/W2011904570","https://openalex.org/W2016775197","https://openalex.org/W2016816293","https://openalex.org/W2016955301","https://openalex.org/W2021889129","https://openalex.org/W2028555435","https://openalex.org/W2029513101","https://openalex.org/W2031930652","https://openalex.org/W2032494769","https://openalex.org/W2035976926","https://openalex.org/W2036143536","https://openalex.org/W2044295326","https://openalex.org/W2046889140","https://openalex.org/W2063207344","https://openalex.org/W2063317400","https://openalex.org/W2064218663","https://openalex.org/W2064771788","https://openalex.org/W2068788882","https://openalex.org/W2071167287","https://openalex.org/W2073421832","https://openalex.org/W2078426615","https://openalex.org/W2079010145","https://openalex.org/W2089491627","https://openalex.org/W2099675490","https://openalex.org/W2100326225","https://openalex.org/W2106228560","https://openalex.org/W2106673834","https://openalex.org/W2106881778","https://openalex.org/W2111914361","https://openalex.org/W2114887853","https://openalex.org/W2118526748","https://openalex.org/W2121380252","https://openalex.org/W2125914414","https://openalex.org/W2142685635","https://openalex.org/W2143758178","https://openalex.org/W2149487482","https://openalex.org/W2159417266","https://openalex.org/W2159999899","https://openalex.org/W2163243408","https://openalex.org/W2167301573","https://openalex.org/W2167871776","https://openalex.org/W2168207084","https://openalex.org/W2169584423","https://openalex.org/W2753211981","https://openalex.org/W4295836001"],"related_works":["https://openalex.org/W1987081782","https://openalex.org/W2014505899","https://openalex.org/W2573698286","https://openalex.org/W2068786130","https://openalex.org/W2557362819","https://openalex.org/W2055044750","https://openalex.org/W2169083662","https://openalex.org/W2585461332","https://openalex.org/W2061116995","https://openalex.org/W2278316388"],"abstract_inverted_index":{"According":[0],"to":[1,71,95],"the":[2,44,73,144],"multistep":[3,146],"model":[4],"of":[5,15,35,55,76,83,143,148],"cell":[6,49,149],"migration,":[7],"chemokine":[8,121],"receptor":[9],"engagement":[10,82],"(step":[11,18,23],"2)":[12],"triggers":[13,88],"conversion":[14],"rolling":[16],"interactions":[17],"1)":[19],"into":[20],"firm":[21],"adhesion":[22,94],"3),":[24],"yielding":[25,138],"transendothelial":[26,111],"migration.":[27,150],"We":[28,79],"recently":[29],"reported":[30],"that":[31,81,126],"glycosyltransferase-programmed":[32],"stereosubstitution":[33],"(GPS)":[34],"CD44":[36,130],"on":[37,113],"human":[38,115],"mesenchymal":[39],"stem":[40],"cells":[41,119],"(hMSCs)":[42],"creates":[43],"E-selectin":[45,87],"ligand":[46,96],"HCELL":[47,85],"(hematopoietic":[48],"E-selectin/L-selectin":[50],"ligand)":[51],"and,":[52],"despite":[53],"absence":[54],"CXCR4,":[56],"systemically":[57],"administered":[58],"HCELL(+)hMSCs":[59],"display":[60],"robust":[61],"osteotropism":[62],"visualized":[63],"by":[64],"intravital":[65],"microscopy.":[66],"Here":[67],"we":[68],"performed":[69],"studies":[70],"define":[72],"molecular":[74],"effectors":[75],"this":[77],"process.":[78],"observed":[80],"hMSC":[84],"with":[86],"VLA-4":[89,99],"adhesiveness,":[90],"resulting":[91,109],"in":[92,110],"shear-resistant":[93],"VCAM-1.":[97],"This":[98],"activation":[100],"is":[101],"mediated":[102],"via":[103],"a":[104,139],"Rac1/Rap1":[105],"GTPase":[106],"signaling":[107],"pathway,":[108],"migration":[112],"stimulated":[114],"umbilical":[116],"vein":[117],"endothelial":[118],"without":[120],"input.":[122],"These":[123],"findings":[124],"indicate":[125],"hMSCs":[127],"coordinately":[128],"integrate":[129],"ligation":[131],"and":[132],"integrin":[133],"activation,":[134],"circumventing":[135],"chemokine-mediated":[136],"signaling,":[137],"step":[140],"2-bypass":[141],"pathway":[142],"canonical":[145],"paradigm":[147]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}