{"id":"https://openalex.org/W1978332734","doi":"https://doi.org/10.1186/1471-2466-14-18","title":"Validation of a portable nitric oxide analyzer for screening in primary ciliary dyskinesias","display_name":"Validation of a portable nitric oxide analyzer for screening in primary ciliary dyskinesias","publication_year":2014,"publication_date":"2014-02-10","ids":{"openalex":"https://openalex.org/W1978332734","doi":"https://doi.org/10.1186/1471-2466-14-18","mag":"1978332734","pmid":"https://pubmed.ncbi.nlm.nih.gov/24507708","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3929562"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2466-14-18","doi":"https://doi.org/10.1186/1471-2466-14-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2466-14-18","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-2466-14-18.pdf","source":{"id":"https://openalex.org/S204956882","display_name":"BMC Pulmonary Medicine","issn_l":"1471-2466","issn":["1471-2466"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pulmonary Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/1471-2466-14-18.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066170576","display_name":"Amanda Lea Harris","orcid":"https://orcid.org/0000-0002-6953-7370","observed_orcids":["https://orcid.org/0000-0002-6953-7370"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210110707","display_name":"NIHR Southampton Respiratory Biomedical Research Unit","ror":"https://ror.org/01yg3ff09","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805","https://openalex.org/I34931013","https://openalex.org/I4210110707","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amanda Harris","raw_affiliation_strings":["NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210110707","https://openalex.org/I43439940"]},{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048387759","display_name":"Esther Bhullar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Esther Bhullar","raw_affiliation_strings":["Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090060579","display_name":"Kerry Gove","orcid":"https://orcid.org/0000-0002-5022-4550","observed_orcids":["https://orcid.org/0000-0002-5022-4550"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210110707","display_name":"NIHR Southampton Respiratory Biomedical Research Unit","ror":"https://ror.org/01yg3ff09","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805","https://openalex.org/I34931013","https://openalex.org/I4210110707","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kerry Gove","raw_affiliation_strings":["NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210110707","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049976032","display_name":"Rhiannon Joslin","orcid":"https://orcid.org/0000-0002-3712-3341","observed_orcids":["https://orcid.org/0000-0002-3712-3341"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rhiannon Joslin","raw_affiliation_strings":["Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007649449","display_name":"Jennifer Pelling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jennifer Pelling","raw_affiliation_strings":["Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033318484","display_name":"Hazel Jean Evans","orcid":"https://orcid.org/0000-0001-9366-556X","observed_orcids":["https://orcid.org/0000-0001-9366-556X"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210110707","display_name":"NIHR Southampton Respiratory Biomedical Research Unit","ror":"https://ror.org/01yg3ff09","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805","https://openalex.org/I34931013","https://openalex.org/I4210110707","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hazel J Evans","raw_affiliation_strings":["NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210110707","https://openalex.org/I43439940"]},{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109069824","display_name":"Woolf T. Walker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210110707","display_name":"NIHR Southampton Respiratory Biomedical Research Unit","ror":"https://ror.org/01yg3ff09","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805","https://openalex.org/I34931013","https://openalex.org/I4210110707","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Woolf T Walker","raw_affiliation_strings":["Clinical and Experimental Sciences Academic Unit (Mail Point 803), University of Southampton Faculty of Medicine, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, UK","NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Experimental Sciences Academic Unit (Mail Point 803), University of Southampton Faculty of Medicine, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I43439940"]},{"raw_affiliation_string":"NIHR Southampton Respiratory Biomedical Research Unit, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210110707","https://openalex.org/I43439940"]},{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045256321","display_name":"Jane S. Lucas","orcid":"https://orcid.org/0000-0001-8701-9975","observed_orcids":["https://orcid.org/0000-0001-8701-9975"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jane S Lucas","raw_affiliation_strings":["Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK. jlucas1@soton.ac.uk","Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK. jlucas1@soton.ac.uk","institution_ids":["https://openalex.org/I2802965805"]},{"raw_affiliation_string":"Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045256321"],"corresponding_institution_ids":["https://openalex.org/I2802965805"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":3.3918,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.92035508,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"1","first_page":"18","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-ciliary-dyskinesia","display_name":"primary ciliary dyskinesia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/nasal-nitric-oxide","display_name":"nasal nitric oxide","score":0.9980000257492065},{"id":"https://openalex.org/keywords/screening-test","display_name":"screening test","score":0.5609999895095825},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.656000018119812},{"id":"https://openalex.org/keywords/repeatability","display_name":"repeatability","score":0.6629999876022339},{"id":"https://openalex.org/keywords/tidal-breathing","display_name":"tidal breathing","score":0.7020000219345093},{"id":"https://openalex.org/keywords/breath-holding","display_name":"breath-holding","score":0.8489999771118164},{"id":"https://openalex.org/keywords/respiratory-diseases","display_name":"respiratory diseases","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C26834552","wikidata":"https://www.wikidata.org/wiki/Q3275846","display_name":"Analyser","level":2,"score":0.975859522819519},{"id":"https://openalex.org/C154020017","wikidata":"https://www.wikidata.org/wiki/Q520171","display_name":"Repeatability","level":2,"score":0.8647944927215576},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7857881784439087},{"id":"https://openalex.org/C2778206077","wikidata":"https://www.wikidata.org/wiki/Q1690779","display_name":"Primary ciliary dyskinesia","level":4,"score":0.7437505722045898},{"id":"https://openalex.org/C158007255","wikidata":"https://www.wikidata.org/wiki/Q1055222","display_name":"Spectrum analyzer","level":2,"score":0.5846498608589172},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.19470509886741638},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13037589192390442},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09125697612762451},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.07980978488922119},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.0},{"id":"https://openalex.org/C2779379686","wikidata":"https://www.wikidata.org/wiki/Q32778","display_name":"Bronchiectasis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003948","descriptor_name":"Diagnostic Techniques, Respiratory System","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007619","descriptor_name":"Kartagener Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007619","descriptor_name":"Kartagener Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1471-2466-14-18","doi":"https://doi.org/10.1186/1471-2466-14-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2466-14-18","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-2466-14-18.pdf","source":{"id":"https://openalex.org/S204956882","display_name":"BMC Pulmonary Medicine","issn_l":"1471-2466","issn":["1471-2466"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pulmonary Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2912140","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3929562","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24507708","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24507708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC pulmonary medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:3929562","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3929562/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pulm Med","raw_type":"Text"},{"id":"pmh:oai:eprints.soton.ac.uk:362848","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/362848/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2466-14-18","doi":"https://doi.org/10.1186/1471-2466-14-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2466-14-18","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-2466-14-18.pdf","source":{"id":"https://openalex.org/S204956882","display_name":"BMC Pulmonary Medicine","issn_l":"1471-2466","issn":["1471-2466"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pulmonary Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978332734.pdf","grobid_xml":"https://content.openalex.org/works/W1978332734.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W34354563","https://openalex.org/W193317673","https://openalex.org/W1872065400","https://openalex.org/W1950411583","https://openalex.org/W1965779264","https://openalex.org/W1974075256","https://openalex.org/W1980526114","https://openalex.org/W1997414873","https://openalex.org/W2023726983","https://openalex.org/W2041847422","https://openalex.org/W2095233893","https://openalex.org/W2097415182","https://openalex.org/W2104946337","https://openalex.org/W2105375033","https://openalex.org/W2105494428","https://openalex.org/W2107980880","https://openalex.org/W2115068324","https://openalex.org/W2150712218","https://openalex.org/W2159320281","https://openalex.org/W2159834153","https://openalex.org/W2164773000","https://openalex.org/W2165265670","https://openalex.org/W2168364283","https://openalex.org/W2229618605","https://openalex.org/W4211006694"],"related_works":["https://openalex.org/W2147840587","https://openalex.org/W2442900909","https://openalex.org/W1910324754","https://openalex.org/W2041847422","https://openalex.org/W1866178728","https://openalex.org/W4406825615","https://openalex.org/W1955509954","https://openalex.org/W2772865288","https://openalex.org/W4411383524","https://openalex.org/W2555155934"],"abstract_inverted_index":{"BACKGROUND:":[0],"Nasal":[1,56],"nitric":[2,38],"oxide":[3,39],"(nNO)":[4],"levels":[5],"are":[6],"very":[7],"low":[8],"in":[9,33,42,102,122],"primary":[10],"ciliary":[11],"dyskinesia":[12],"(PCD)":[13],"and":[14,27,69,92,109,138,152,187],"it":[15],"is":[16],"used":[17],"as":[18,94,154],"a":[19,30,36,61,66,71,95,155,207],"screening":[20,156,209],"test.":[21],"METHODS:":[22],"We":[23],"assessed":[24],"the":[25,127,132,173],"reliability":[26],"usability":[28],"of":[29,124,164,197],"hand-held":[31,72,133,144,188,203],"analyser":[32,41,64,73,134,175,189,205],"comparison":[34],"to":[35],"stationary":[37,62,128,174,186],"(NO)":[40],"50":[43],"participants":[44,125],"(15":[45],"healthy,":[46],"13":[47],"PCD,":[48,98],"22":[49],"other":[50],"respiratory":[51],"diseases;":[52],"age":[53,104],"6-79":[54],"years).":[55],"NO":[57,63,204],"was":[58,114,178],"measured":[59],"using":[60,70,126,131,172],"during":[65,74,160,176],"breath-holding":[67],"maneuver,":[68],"tidal":[75,161],"breathing,":[76],"sampling":[77],"at":[78,135,140,146],"2":[79,141],"ml/sec":[80,137,148],"or":[81],"5":[82,136,147],"ml/sec.":[83,142],"The":[84,143,170,185,202],"three":[85],"methods":[86,113],"were":[87,120],"compared":[88],"for":[89,97,158,211],"their":[90,99],"specificity":[91,153],"sensitivity":[93,151],"screen":[96],"success":[100],"rate":[101],"different":[103],"groups,":[105],"within":[106],"subject":[107],"repeatability":[108],"acceptability.":[110],"Correlation":[111],"between":[112],"assessed.":[115],"RESULTS:":[116],"Valid":[117],"nNO":[118],"measurements":[119],"obtained":[121],"94%":[123],"analyser,":[129],"96%":[130],"76%":[139],"device":[145],"had":[149],"excellent":[150],"test":[157],"PCD":[159],"breathing":[162],"(cut-off":[163],"30":[165],"nL/min,100%":[166],"sensitivity,":[167,182],">95%":[168],"specificity).":[169,184],"cut-off":[171],"breath-hold":[177],"38":[179],"nL/min":[180],"(100%":[181],"95%":[183],"(5":[190],"ml/sec)":[191],"showed":[192],"reasonable":[193],"within-subject":[194],"repeatability(%":[195],"coefficient":[196],"variation":[198],"=":[199],"15).":[200],"CONCLUSION:":[201],"provides":[206],"promising":[208],"tool":[210],"PCD.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}