{"id":"https://openalex.org/W1978306592","doi":"https://doi.org/10.1016/s1474-4422(07)70265-x","title":"Cognitive impairment in amyotrophic lateral sclerosis","display_name":"Cognitive impairment in amyotrophic lateral sclerosis","publication_year":2007,"publication_date":"2007-11-01","ids":{"openalex":"https://openalex.org/W1978306592","doi":"https://doi.org/10.1016/s1474-4422(07)70265-x","mag":"1978306592","pmid":"https://pubmed.ncbi.nlm.nih.gov/17945153"},"language":"en","primary_location":{"id":"doi:10.1016/s1474-4422(07)70265-x","doi":"https://doi.org/10.1016/s1474-4422(07)70265-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1474-4422(07)70265-x","pdf_url":null,"source":{"id":"https://openalex.org/S70053155","display_name":"The Lancet Neurology","issn_l":"1474-4422","issn":["1474-4422","1474-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Neurology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023693573","display_name":"Julie Phukan","orcid":"https://orcid.org/0009-0003-2373-4357","observed_orcids":["https://orcid.org/0009-0003-2373-4357"]},"institutions":[{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Julie Phukan","raw_affiliation_strings":["Department of Neurology, Beaumont Hospital, Dublin, Ireland. juliephukan@yahoo.co.uk","Department of Neurology Beaumont Hospital, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Beaumont Hospital, Dublin, Ireland. juliephukan@yahoo.co.uk","institution_ids":["https://openalex.org/I2801846703"]},{"raw_affiliation_string":"Department of Neurology Beaumont Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I2801846703"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041794787","display_name":"Niall P Pender","orcid":"https://orcid.org/0000-0002-4172-0704","observed_orcids":["https://orcid.org/0000-0002-4172-0704"]},"institutions":[{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Niall P Pender","raw_affiliation_strings":["Department of Psychology, Beaumont Hospital, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Beaumont Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I2801846703"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030609927","display_name":"Orla M. Hardiman","orcid":"https://orcid.org/0000-0003-2610-1291","observed_orcids":["https://orcid.org/0000-0003-2610-1291"]},"institutions":[{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Orla Hardiman","raw_affiliation_strings":["Department of Neurology, Beaumont Hospital, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Beaumont Hospital, Dublin, Ireland","institution_ids":["https://openalex.org/I2801846703"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023693573"],"corresponding_institution_ids":["https://openalex.org/I2801846703"],"apc_list":{"value":7280,"currency":"USD","value_usd":7280},"apc_paid":null,"fwci":3.8516,"has_fulltext":false,"cited_by_count":635,"citation_normalized_percentile":{"value":0.96508564,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"6","issue":"11","first_page":"994","last_page":"1003"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.9980000257492065},{"id":"https://openalex.org/keywords/frontotemporal-dementia","display_name":"frontotemporal dementia","score":0.9729999899864197},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.5590000152587891},{"id":"https://openalex.org/keywords/personality-change","display_name":"personality change","score":0.7590000033378601},{"id":"https://openalex.org/keywords/irritability","display_name":"irritability","score":0.7039999961853027},{"id":"https://openalex.org/keywords/neuropsychological-assessment","display_name":"neuropsychological assessment","score":0.7929999828338623},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.6579999923706055},{"id":"https://openalex.org/keywords/shared-genetic-architecture","display_name":"genetic overlap","score":0.5189999938011169},{"id":"https://openalex.org/keywords/neuropathology","display_name":"neuropathology","score":0.7139999866485596},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"neuroimaging","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.8655703067779541},{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.8257231712341309},{"id":"https://openalex.org/C2779985164","wikidata":"https://www.wikidata.org/wiki/Q5419936","display_name":"Executive dysfunction","level":4,"score":0.5793908834457397},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5166385769844055},{"id":"https://openalex.org/C2777898937","wikidata":"https://www.wikidata.org/wiki/Q5008447","display_name":"C9orf72","level":5,"score":0.506362795829773},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.4973314106464386},{"id":"https://openalex.org/C2775968953","wikidata":"https://www.wikidata.org/wiki/Q783092","display_name":"Executive functions","level":3,"score":0.49139347672462463},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.48921751976013184},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.46919935941696167},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4619811475276947},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4578058421611786},{"id":"https://openalex.org/C2776939681","wikidata":"https://www.wikidata.org/wiki/Q18579","display_name":"Frontotemporal lobar degeneration","level":5,"score":0.44675564765930176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42207491397857666},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.41678786277770996},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.324238121509552},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.32079845666885376},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13353800773620605}],"mesh":[{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1474-4422(07)70265-x","doi":"https://doi.org/10.1016/s1474-4422(07)70265-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1474-4422(07)70265-x","pdf_url":null,"source":{"id":"https://openalex.org/S70053155","display_name":"The Lancet Neurology","issn_l":"1474-4422","issn":["1474-4422","1474-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Neurology","raw_type":"journal-article"},{"id":"pmid:17945153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17945153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet. Neurology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W191367575","https://openalex.org/W1503404806","https://openalex.org/W1521476494","https://openalex.org/W1607830031","https://openalex.org/W1894493322","https://openalex.org/W1964224717","https://openalex.org/W1968087008","https://openalex.org/W1970906990","https://openalex.org/W1972919693","https://openalex.org/W1974583546","https://openalex.org/W1975579923","https://openalex.org/W1976832883","https://openalex.org/W1980448435","https://openalex.org/W1984979116","https://openalex.org/W1985199662","https://openalex.org/W1989353506","https://openalex.org/W1992661874","https://openalex.org/W1996319685","https://openalex.org/W2003618511","https://openalex.org/W2003858435","https://openalex.org/W2005731595","https://openalex.org/W2007541499","https://openalex.org/W2010681077","https://openalex.org/W2012996864","https://openalex.org/W2015589461","https://openalex.org/W2016878348","https://openalex.org/W2017458896","https://openalex.org/W2022026916","https://openalex.org/W2023556666","https://openalex.org/W2027460468","https://openalex.org/W2027742580","https://openalex.org/W2042450904","https://openalex.org/W2043656638","https://openalex.org/W2046659397","https://openalex.org/W2047435344","https://openalex.org/W2047626780","https://openalex.org/W2053362200","https://openalex.org/W2054652067","https://openalex.org/W2055858689","https://openalex.org/W2056607803","https://openalex.org/W2057488577","https://openalex.org/W2059409309","https://openalex.org/W2063183749","https://openalex.org/W2065488153","https://openalex.org/W2068565521","https://openalex.org/W2072572637","https://openalex.org/W2073275883","https://openalex.org/W2076788657","https://openalex.org/W2079781210","https://openalex.org/W2081278216","https://openalex.org/W2088945561","https://openalex.org/W2089331778","https://openalex.org/W2089390830","https://openalex.org/W2090803895","https://openalex.org/W2092283398","https://openalex.org/W2095421238","https://openalex.org/W2102262051","https://openalex.org/W2103362905","https://openalex.org/W2103958490","https://openalex.org/W2107062472","https://openalex.org/W2107734568","https://openalex.org/W2110646851","https://openalex.org/W2116166477","https://openalex.org/W2116982426","https://openalex.org/W2126671539","https://openalex.org/W2130202191","https://openalex.org/W2132837027","https://openalex.org/W2133344031","https://openalex.org/W2133702405","https://openalex.org/W2135031277","https://openalex.org/W2135610185","https://openalex.org/W2136623481","https://openalex.org/W2137466608","https://openalex.org/W2141365662","https://openalex.org/W2141836397","https://openalex.org/W2142177996","https://openalex.org/W2144871118","https://openalex.org/W2146300304","https://openalex.org/W2147729862","https://openalex.org/W2156995175","https://openalex.org/W2162531402","https://openalex.org/W2163837340","https://openalex.org/W2164647869","https://openalex.org/W2166130753","https://openalex.org/W2166281097","https://openalex.org/W2168252746","https://openalex.org/W2171303338","https://openalex.org/W2316682551","https://openalex.org/W2600536710","https://openalex.org/W2602425071","https://openalex.org/W4230273980","https://openalex.org/W4251881718","https://openalex.org/W6636236678"],"related_works":["https://openalex.org/W2019279972","https://openalex.org/W2123293695","https://openalex.org/W4396750783","https://openalex.org/W3153761310","https://openalex.org/W4387138915","https://openalex.org/W3081033880","https://openalex.org/W3004516419","https://openalex.org/W3144267052","https://openalex.org/W2066143700","https://openalex.org/W2491164417"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":35},{"year":2023,"cited_by_count":39},{"year":2022,"cited_by_count":31},{"year":2021,"cited_by_count":41},{"year":2020,"cited_by_count":31},{"year":2019,"cited_by_count":27},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":33},{"year":2016,"cited_by_count":43},{"year":2015,"cited_by_count":35},{"year":2014,"cited_by_count":39},{"year":2013,"cited_by_count":36},{"year":2012,"cited_by_count":47}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
