{"id":"https://openalex.org/W1978302134","doi":"https://doi.org/10.1253/circj.66.494","title":"Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.","display_name":"Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images.","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W1978302134","doi":"https://doi.org/10.1253/circj.66.494","mag":"1978302134","pmid":"https://pubmed.ncbi.nlm.nih.gov/12030347"},"language":"en","primary_location":{"id":"doi:10.1253/circj.66.494","doi":"https://doi.org/10.1253/circj.66.494","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.66.494","pdf_url":"https://www.jstage.jst.go.jp/article/circj/66/5/66_5_494/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/circj/66/5/66_5_494/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110340007","display_name":"Hidetoshi Yoshitani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidetoshi Yoshitani","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013432648","display_name":"Masaaki Takeuchi","orcid":"https://orcid.org/0000-0001-7606-1537","observed_orcids":["https://orcid.org/0000-0001-7606-1537"]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Takeuchi","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048098751","display_name":"Makoto Hirose","orcid":"https://orcid.org/0009-0001-6631-8623","observed_orcids":["https://orcid.org/0009-0001-6631-8623"]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Hirose","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036274841","display_name":"Chinami Miyazaki","orcid":"https://orcid.org/0000-0002-2639-8358","observed_orcids":["https://orcid.org/0000-0002-2639-8358"]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chinami Miyazaki","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111731758","display_name":"Shinichiro Otani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichiro Otani","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073774735","display_name":"Kazuo Sakamoto","orcid":"https://orcid.org/0000-0003-1252-5683","observed_orcids":["https://orcid.org/0000-0003-1252-5683"]},"institutions":[{"id":"https://openalex.org/I4210131591","display_name":"Tane General Hospital","ror":"https://ror.org/03c1y0r66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131591"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuo Sakamoto","raw_affiliation_strings":["Department of Internal Medicine, Tane General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Tane General Hospital","institution_ids":["https://openalex.org/I4210131591"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026433163","display_name":"Junichi Yoshikawa","orcid":"https://orcid.org/0000-0003-1490-1558","observed_orcids":["https://orcid.org/0000-0003-1490-1558"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junichi Yoshikawa","raw_affiliation_strings":["Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University","institution_ids":["https://openalex.org/I317356780"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0571,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.79439252,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"66","issue":"5","first_page":"494","last_page":"498"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.33570000529289246,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.027799999341368675,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-harmonic-imaging","display_name":"tissue harmonic imaging","score":0.8289999961853027},{"id":"https://openalex.org/keywords/contrast-harmonic-imaging","display_name":"contrast harmonic imaging","score":0.9940000176429749},{"id":"https://openalex.org/keywords/levovist","display_name":"Levovist","score":0.8939999938011169},{"id":"https://openalex.org/keywords/endocardial-border-delineation","display_name":"endocardial border delineation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/left-ventricle","display_name":"left ventricle","score":0.8640000224113464},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C164323173","wikidata":"https://www.wikidata.org/wiki/Q17092959","display_name":"Second-harmonic imaging microscopy","level":4,"score":0.9364067912101746},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.6999939680099487},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6914535760879517},{"id":"https://openalex.org/C127934551","wikidata":"https://www.wikidata.org/wiki/Q1148098","display_name":"Harmonic","level":2,"score":0.6014689803123474},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5238949060440063},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.4854760468006134},{"id":"https://openalex.org/C138010386","wikidata":"https://www.wikidata.org/wiki/Q6804531","display_name":"Mechanical index","level":4,"score":0.42122000455856323},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.36138150095939636},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.35550546646118164},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.17667394876480103},{"id":"https://openalex.org/C30713254","wikidata":"https://www.wikidata.org/wiki/Q1455635","display_name":"Second-harmonic generation","level":3,"score":0.1574801802635193},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.11320048570632935},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10505935549736023},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.1015622615814209},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08986237645149231},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.08669653534889221},{"id":"https://openalex.org/C64012434","wikidata":"https://www.wikidata.org/wiki/Q6839290","display_name":"Microbubbles","level":3,"score":0.0833650529384613},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.07661432027816772},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06997331976890564},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004699","descriptor_name":"Endocardium","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1253/circj.66.494","doi":"https://doi.org/10.1253/circj.66.494","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.66.494","pdf_url":"https://www.jstage.jst.go.jp/article/circj/66/5/66_5_494/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},{"id":"pmid:12030347","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12030347","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation journal : official journal of the Japanese Circulation Society","raw_type":"Comparative Study"},{"id":"mag:3215294322","doi":null,"is_oa":false,"landing_page_url":"https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902151808208458","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":{"id":"doi:10.1253/circj.66.494","doi":"https://doi.org/10.1253/circj.66.494","is_oa":true,"landing_page_url":"https://doi.org/10.1253/circj.66.494","pdf_url":"https://www.jstage.jst.go.jp/article/circj/66/5/66_5_494/_pdf","source":{"id":"https://openalex.org/S4210176241","display_name":"Circulation Journal","issn_l":"1346-9843","issn":["1346-9843","1347-4820"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310313287","host_organization_name":"Japanese Circulation Society","host_organization_lineage":["https://openalex.org/P4310313287"],"host_organization_lineage_names":["Japanese Circulation Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978302134.pdf","grobid_xml":"https://content.openalex.org/works/W1978302134.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1577819988","https://openalex.org/W1977086661","https://openalex.org/W1981728640","https://openalex.org/W1983724603","https://openalex.org/W1997415562","https://openalex.org/W1998579781","https://openalex.org/W2015530085","https://openalex.org/W2023052045","https://openalex.org/W2050901984","https://openalex.org/W2078313789","https://openalex.org/W2082854079","https://openalex.org/W2083325263","https://openalex.org/W2085892480","https://openalex.org/W2094491905","https://openalex.org/W2161235932","https://openalex.org/W2176848914","https://openalex.org/W2289972103","https://openalex.org/W2330400714","https://openalex.org/W2345840476","https://openalex.org/W2411224612"],"related_works":["https://openalex.org/W2405962473","https://openalex.org/W2082854079","https://openalex.org/W2139933538","https://openalex.org/W1984233857","https://openalex.org/W2464136747","https://openalex.org/W2022795675","https://openalex.org/W4256547718","https://openalex.org/W2050901984","https://openalex.org/W2021611041","https://openalex.org/W2088426715"],"abstract_inverted_index":{"Recent":[0],"developments":[1],"in":[2,206],"tissue":[3,37,121,144,183,215],"harmonic":[4,38,41,122,145,155,184,191,216,219,222],"imaging":[5,42,112,123,129,146,156,163,185,192,223],"and":[6,30,39,61,113,124,149,176,189,220],"intravenous":[7,46],"contrast":[8,40,50,154,190,221],"agents":[9],"have":[10],"enhanced":[11,196],"left":[12,53],"ventricular":[13],"endocardial":[14,88],"border":[15],"delineation":[16],"(EBD).":[17],"In":[18],"a":[19,99],"total":[20,100],"of":[21,64,86,101,134,172],"48":[22],"patients":[23],"with":[24,35,43,130,147,157,169,193,214],"poor":[25],"quality":[26],"images,":[27],"apical":[28],"4-":[29],"2-chamber":[31],"views":[32],"were":[33,106],"obtained":[34,94,213],"fundamental,":[36],"or":[44],"without":[45],"Levovist,":[47,148],"an":[48],"air-filled":[49],"agent.":[51],"The":[52,78,132,159],"ventricle":[54],"(LV)":[55],"was":[56,67,93,164,177],"divided":[57,90],"into":[58],"12":[59,92],"segments,":[60,104],"the":[62,84,87,170,197,207,211,225],"EBD":[63,79,230],"each":[65,96],"segment":[66],"scored:":[68],"(1)":[69],"not":[70],"visible,":[71,74],"(2)":[72],"barely":[73],"(3)":[75],"well":[76],"delineated.":[77],"index":[80],"(EBDI),":[81],"defined":[82],"as":[83,108,137],"sum":[85],"scores":[89],"by":[91,110,120,127,143,153,161,182],"for":[95,228],"patient.":[97],"Of":[98],"576":[102],"LV":[103],"231":[105],"scored":[107,136],"1":[109,138],"fundamental":[111,128,162,208],"that":[114,181],"number":[115,133],"decreased":[116,139],"to":[117,140,150,180,210],"125":[118],"segments":[119,126,135,142,152],"116":[125],"Levovist.":[131,158],"38":[141],"29":[151],"EBDI":[160,198],"1.85+/-0.29,":[165],"which":[166],"improved":[167],"significantly":[168],"addition":[171],"Levovist":[173,194,202,232],"(2.10+/-0.36,":[174],"p<0.001)":[175],"nearly":[178],"identical":[179],"(2.15+/-0.32,":[186],"p=NS).":[187],"Tissue":[188,218],"further":[195],"(2.43+/-0.26,":[199],"2.51+/-0.27,":[200],"respectively).":[201],"enhances":[203],"EBD,":[204],"even":[205],"mode,":[209],"level":[212],"imaging.":[217],"are":[224],"best":[226],"modalities":[227],"enhancing":[229],"after":[231],"injection.":[233]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}