{"id":"https://openalex.org/W1978282269","doi":"https://doi.org/10.1159/000168747","title":"Jacob Henle: The Kidney and Beyond","display_name":"Jacob Henle: The Kidney and Beyond","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W1978282269","doi":"https://doi.org/10.1159/000168747","mag":"1978282269","pmid":"https://pubmed.ncbi.nlm.nih.gov/7847468"},"language":"en","primary_location":{"id":"doi:10.1159/000168747","doi":"https://doi.org/10.1159/000168747","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000168747","pdf_url":null,"source":{"id":"https://openalex.org/S106979888","display_name":"American Journal of Nephrology","issn_l":"0250-8095","issn":["0250-8095","1421-9670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110199063","display_name":"Evamaria Kinne-Saffran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130622","display_name":"Max Planck Institute of Molecular Physiology","ror":"https://ror.org/03vpj4s62","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210130622"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Evamaria KinneSaffran","raw_affiliation_strings":["Max Planck Institut f\u00fcr Molekulare Physiologie, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institut f\u00fcr Molekulare Physiologie, Dortmund, Germany","institution_ids":["https://openalex.org/I4210130622"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017423382","display_name":"Rolf K. H. Kinne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130622","display_name":"Max Planck Institute of Molecular Physiology","ror":"https://ror.org/03vpj4s62","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210130622"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Rolf K.H. Kinne","raw_affiliation_strings":["Max-Planck-Institut f\u00fcr molekulare Physiologie, Dortmund, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max-Planck-Institut f\u00fcr molekulare Physiologie, Dortmund, Germany","institution_ids":["https://openalex.org/I4210130622"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017423382"],"corresponding_institution_ids":["https://openalex.org/I4210130622"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.24586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"14","issue":"4-6","first_page":"355","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14475","display_name":"History of Science and Medicine","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T14475","display_name":"History of Science and Medicine","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/1207","display_name":"History and Philosophy of Science"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12990","display_name":"Medical History and Innovations","score":0.21529999375343323,"subfield":{"id":"https://openalex.org/subfields/1202","display_name":"History"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12324","display_name":"History of Medicine Studies","score":0.014100000262260437,"subfield":{"id":"https://openalex.org/subfields/1202","display_name":"History"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/history-of-nephrology","display_name":"history of nephrology","score":0.8820000290870667},{"id":"https://openalex.org/keywords/kidney","display_name":"kidney","score":0.5170000195503235},{"id":"https://openalex.org/keywords/renal-tubules","display_name":"renal tubules","score":0.9449999928474426},{"id":"https://openalex.org/keywords/achromatic-lens","display_name":"achromatic lens","score":0.6489999890327454},{"id":"https://openalex.org/keywords/light-microscopy","display_name":"optical microscopy","score":0.8379999995231628},{"id":"https://openalex.org/keywords/tissue-classification","display_name":"tissue classification","score":0.5960000157356262},{"id":"https://openalex.org/keywords/bichat","display_name":"Bichat","score":0.847000002861023},{"id":"https://openalex.org/keywords/cell-physiology","display_name":"cell physiology","score":0.6100000143051147},{"id":"https://openalex.org/keywords/microorganisms","display_name":"microorganisms","score":0.5540000200271606},{"id":"https://openalex.org/keywords/nineteenth-century-science","display_name":"19th-century science","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.4350987672805786},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3871018886566162},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34995827078819275},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3444225490093231},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31408628821372986},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.251152902841568}],"mesh":[{"descriptor_ui":"D005858","descriptor_name":"Germany","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008138","descriptor_name":"Loop of Henle","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D009398","descriptor_name":"Nephrology","qualifier_ui":"Q000266","qualifier_name":"history","is_major_topic":true},{"descriptor_ui":"D049672","descriptor_name":"History, 19th Century","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000168747","doi":"https://doi.org/10.1159/000168747","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000168747","pdf_url":null,"source":{"id":"https://openalex.org/S106979888","display_name":"American Journal of Nephrology","issn_l":"0250-8095","issn":["0250-8095","1421-9670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Nephrology","raw_type":"journal-article"},{"id":"pmid:7847468","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7847468","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of nephrology","raw_type":"Biography"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2142115684","https://openalex.org/W2241354136","https://openalex.org/W2496286033","https://openalex.org/W2604063754","https://openalex.org/W2217689800","https://openalex.org/W4322392842","https://openalex.org/W4241919158","https://openalex.org/W4230428116","https://openalex.org/W2727936700","https://openalex.org/W2147819072"],"abstract_inverted_index":{"The":[0,19],"progress":[1,96],"in":[2,11,15,24,87,97,125,173,182],"science":[3],"made":[4,26],"by":[5],"Henle":[6,30],"depended":[7],"on":[8],"the":[9,16,39,48,52,71,89,92,102,115,126,133,139,154,162],"improvements":[10],"light":[12],"microscopy":[13],"achieved":[14],"19th":[17],"century.":[18],"advent":[20],"of":[21,42,54,62,74,76,80,91,106,117,128,136,141,157,161],"achromatic":[22],"lenses":[23],"particular":[25],"it":[27],"possible":[28],"for":[29],"and":[31,34,67,99,176],"his":[32,168,174],"contemporary":[33],"friend":[35],"Schwann":[36],"to":[37,51,114,149,189],"uncover":[38],"typical":[40],"structures":[41],"cells,":[43],"thus":[44],"bringing":[45],"order":[46],"at":[47],"microscopic":[49],"level":[50],"world":[53],"living":[55],"tissues.":[56],"Henle's":[57,109],"'comprehensive'":[58],"approach--4":[59],"basic":[60],"types":[61,79],"tissue:":[63],"epithelial,":[64],"connective,":[65],"muscular":[66],"nervous,":[68],"contrasted":[69],"with":[70,94],"accepted":[72],"doctrine":[73],"Bichat":[75],"21":[77],"different":[78,85],"tissues":[81],"that":[82,151,165],"enter":[83],"into":[84],"combinations":[86],"forming":[88],"organs":[90],"body--together":[93],"rapid":[95],"chemistry":[98],"physics":[100],"permitted":[101],"subsequent":[103],"intimate":[104],"probing":[105],"cellular":[107],"physiology.":[108],"work":[110],"was":[111,146],"not":[112,147],"confined":[113],"description":[116],"anatomic":[118],"structures.":[119],"After":[120],"he":[121,131,144,178,184],"had":[122],"observed":[123],"microorganisms":[124,152],"excretions":[127],"diseased":[129],"animals,":[130],"embraced":[132],"unpopular":[134],"theory":[135],"'contagion'":[137],"as":[138,188],"source":[140],"infection,":[142],"though":[143],"himself":[145],"able":[148],"prove":[150],"were":[153],"direct":[155],"cause":[156],"diseases.":[158],"His":[159],"discovery":[160],"renal":[163],"tubule":[164],"now":[166],"bears":[167],"name":[169],"came":[170],"comparatively":[171],"late":[172],"career,":[175],"although":[177],"described":[179],"its":[180,190],"structure":[181],"detail":[183],"offered":[185],"no":[186],"suggestions":[187],"function.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}