{"id":"https://openalex.org/W1978127097","doi":"https://doi.org/10.1378/chest.103.4.1178","title":"Allergen-induced Recruitment of Inflammatory Cells in Lavage 3 and 24 h After Challenge in Allergic Asthmatic Lungs","display_name":"Allergen-induced Recruitment of Inflammatory Cells in Lavage 3 and 24 h After Challenge in Allergic Asthmatic Lungs","publication_year":1993,"publication_date":"1993-04-01","ids":{"openalex":"https://openalex.org/W1978127097","doi":"https://doi.org/10.1378/chest.103.4.1178","mag":"1978127097","pmid":"https://pubmed.ncbi.nlm.nih.gov/8131461"},"language":"en","primary_location":{"id":"doi:10.1378/chest.103.4.1178","doi":"https://doi.org/10.1378/chest.103.4.1178","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.103.4.1178","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108525798","display_name":"Ren\u00e9 Aalbers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Ren\u00e9 Aalbers","raw_affiliation_strings":["Department of Allergology, University Hospital, Groningen, The Netherlands","From the Department of Allergology, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergology, University Hospital, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907"]},{"raw_affiliation_string":"From the Department of Allergology, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113683792","display_name":"Henk F. Kauffman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Henk F. Kauffman","raw_affiliation_strings":["From the Department of Allergology, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Allergology, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024948228","display_name":"Bart Vrugt","orcid":"https://orcid.org/0000-0001-6063-832X","observed_orcids":["https://orcid.org/0000-0001-6063-832X","https://orcid.org/0009-0008-2980-5685"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Bart Vrugt","raw_affiliation_strings":["Clinic for Internal Medicine, and Department of Pathology, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic for Internal Medicine, and Department of Pathology, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109545473","display_name":"Gerard H. Ko\u00ebter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Gerard H. Ko\u00ebter","raw_affiliation_strings":["Department of Pulmonology, University Hospital, Groningen, the Netherlands","Dept. of Pulmonology, University Hospital, Groningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonology, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]},{"raw_affiliation_string":"Dept. of Pulmonology, University Hospital, Groningen, The Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110225816","display_name":"Jan G.R. de Monchy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jan G.R. de Monchy","raw_affiliation_strings":["From the Department of Allergology, University Hospital, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Allergology, University Hospital, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108525798"],"corresponding_institution_ids":["https://openalex.org/I1334415907"],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":2.9918,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.91550501,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"103","issue":"4","first_page":"1178","last_page":"1184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergic-asthma","display_name":"allergic asthma","score":0.9929999709129333},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.8069999814033508},{"id":"https://openalex.org/keywords/eosinophil-cationic-protein","display_name":"eosinophil cationic protein","score":0.9490000009536743},{"id":"https://openalex.org/keywords/airway-hyperresponsiveness","display_name":"airway hyperresponsiveness","score":0.8669999837875366},{"id":"https://openalex.org/keywords/late-asthmatic-reaction","display_name":"late asthmatic response","score":0.9470000267028809},{"id":"https://openalex.org/keywords/early-asthmatic-reaction","display_name":"early asthmatic reaction","score":0.8510000109672546},{"id":"https://openalex.org/keywords/bronchial-lavage","display_name":"bronchial lavage","score":0.7929999828338623},{"id":"https://openalex.org/keywords/bronchoalveolar-lavage","display_name":"bronchoalveolar lavage","score":1.0},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.6819999814033508},{"id":"https://openalex.org/keywords/airway-inflammation","display_name":"airway inflammation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/allergen-challenge","display_name":"allergen challenge","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C2777961210","wikidata":"https://www.wikidata.org/wiki/Q927148","display_name":"Bronchoalveolar lavage","level":3,"score":0.9621323347091675},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8873579502105713},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.7442162036895752},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.7033891081809998},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6796926259994507},{"id":"https://openalex.org/C2776238763","wikidata":"https://www.wikidata.org/wiki/Q3801533","display_name":"Bronchial hyperresponsiveness","level":4,"score":0.6185455322265625},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.4348789155483246},{"id":"https://openalex.org/C88675164","wikidata":"https://www.wikidata.org/wiki/Q22677314","display_name":"Eosinophil cationic protein","level":4,"score":0.42668619751930237},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3697410225868225},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.32520657777786255},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2126528024673462},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18368840217590332}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001980","descriptor_name":"Bronchi","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001985","descriptor_name":"Bronchial Provocation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001992","descriptor_name":"Bronchoalveolar Lavage Fluid","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006684","descriptor_name":"HLA-DR Antigens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008925","descriptor_name":"Mites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1378/chest.103.4.1178","doi":"https://doi.org/10.1378/chest.103.4.1178","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.103.4.1178","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},{"id":"pmid:8131461","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8131461","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"Journal Article"},{"id":"pmh:oai:pure.rug.nl:openaire_cris_publications/11c4db38-248b-424d-ac4b-2284fe2aff5b","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/11c4db38-248b-424d-ac4b-2284fe2aff5b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AALBERS, R, KAUFFMAN, HF, VRUGT, B, KOETER, GH & DEMONCHY, JGR 1993, 'ALLERGEN-INDUCED RECRUITMENT OF INFLAMMATORY CELLS IN LAVAGE 3 AND 24 H AFTER CHALLENGE IN ALLERGIC ASTHMATIC LUNGS', Chest, vol. 103, no. 4, pp. 1178-1184.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/11c4db38-248b-424d-ac4b-2284fe2aff5b","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/11c4db38-248b-424d-ac4b-2284fe2aff5b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chest, 103(4), 1178 - 1184. ELSEVIER SCIENCE BV","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1480813099","https://openalex.org/W1657740120","https://openalex.org/W1927697103","https://openalex.org/W1936491616","https://openalex.org/W1979415936","https://openalex.org/W1979874532","https://openalex.org/W1983413329","https://openalex.org/W2000470005","https://openalex.org/W2003851888","https://openalex.org/W2018030971","https://openalex.org/W2018123076","https://openalex.org/W2028782302","https://openalex.org/W2029933879","https://openalex.org/W2031880739","https://openalex.org/W2049239278","https://openalex.org/W2065719831","https://openalex.org/W2069587720","https://openalex.org/W2072387879","https://openalex.org/W2072425850","https://openalex.org/W2072529555","https://openalex.org/W2101210820","https://openalex.org/W2114518763","https://openalex.org/W2114805324","https://openalex.org/W2116313488","https://openalex.org/W2120012263","https://openalex.org/W2126609403","https://openalex.org/W2151151601","https://openalex.org/W2151235746","https://openalex.org/W2154945180","https://openalex.org/W2261761153","https://openalex.org/W2290081109","https://openalex.org/W2316050734","https://openalex.org/W6640353557"],"related_works":["https://openalex.org/W1991972193","https://openalex.org/W2151151601","https://openalex.org/W2142151910","https://openalex.org/W2042365002","https://openalex.org/W1979166188","https://openalex.org/W2042140131","https://openalex.org/W29304431","https://openalex.org/W2065719831","https://openalex.org/W2064011660","https://openalex.org/W1936491616"],"abstract_inverted_index":null,"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}