{"id":"https://openalex.org/W1978098692","doi":"https://doi.org/10.1089/cbr.2010.0847","title":"Image-Guided Percutaneous 125 I Seed Implantation as a Salvage Treatment for Recurrent Soft Tissue Sarcomas After Surgery and Radiotherapy","display_name":"Image-Guided Percutaneous 125 I Seed Implantation as a Salvage Treatment for Recurrent Soft Tissue Sarcomas After Surgery and Radiotherapy","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W1978098692","doi":"https://doi.org/10.1089/cbr.2010.0847","mag":"1978098692","pmid":"https://pubmed.ncbi.nlm.nih.gov/21355782"},"language":"en","primary_location":{"id":"doi:10.1089/cbr.2010.0847","doi":"https://doi.org/10.1089/cbr.2010.0847","is_oa":false,"landing_page_url":"https://doi.org/10.1089/cbr.2010.0847","pdf_url":null,"source":{"id":"https://openalex.org/S87235987","display_name":"Cancer Biotherapy and Radiopharmaceuticals","issn_l":"1084-9785","issn":["1084-9785","1557-8852"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biotherapy and Radiopharmaceuticals","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Jinna Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinna Li","raw_affiliation_strings":["Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100395790","display_name":"Junjie Wang","orcid":"https://orcid.org/0000-0002-1388-076X","observed_orcids":["https://orcid.org/0000-0002-1388-076X"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Junjie Wang","raw_affiliation_strings":["Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102006933","display_name":"Na Meng","orcid":"https://orcid.org/0000-0002-5234-8872","observed_orcids":["https://orcid.org/0000-0002-5234-8872"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Na Meng","raw_affiliation_strings":["Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103216946","display_name":"Ang Qu","orcid":"https://orcid.org/0000-0002-7169-1780","observed_orcids":["https://orcid.org/0000-0002-7169-1780","https://orcid.org/0000-0001-6820-4091"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ang Qu","raw_affiliation_strings":["Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046925448","display_name":"Huishu Yuan","orcid":"https://orcid.org/0000-0002-5320-4360","observed_orcids":["https://orcid.org/0000-0002-5320-4360","https://orcid.org/0009-0007-3784-2331"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huishu Yuan","raw_affiliation_strings":["Department of Radiology, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322216","display_name":"Chen Liu","orcid":"https://orcid.org/0009-0003-0430-6146","observed_orcids":["https://orcid.org/0009-0003-0430-6146","https://orcid.org/0009-0008-6552-1719"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Liu","raw_affiliation_strings":["Department of Radiology, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112507561","display_name":"Weiqiang Ran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiqiang Ran","raw_affiliation_strings":["Department of Ultrasound, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052375520","display_name":"Yuliang Jiang","orcid":"https://orcid.org/0000-0001-5627-8296","observed_orcids":["https://orcid.org/0000-0001-5627-8296"]},"institutions":[{"id":"https://openalex.org/I4210141942","display_name":"Peking University Third Hospital","ror":"https://ror.org/04wwqze12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141942"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuliang Jiang","raw_affiliation_strings":["Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210141942"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100395790"],"corresponding_institution_ids":["https://openalex.org/I4210141942"],"apc_list":null,"apc_paid":null,"fwci":0.8158,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.76436719,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"26","issue":"1","first_page":"113","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12278","display_name":"Vascular Tumors and Angiosarcomas","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iodine-125-seed-implantation","display_name":"iodine-125 seed implantation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/brachytherapy","display_name":"brachytherapy","score":0.7450000047683716},{"id":"https://openalex.org/keywords/recurrent-soft-tissue-sarcoma","display_name":"recurrent soft tissue sarcoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/salvage-therapy","display_name":"salvage therapy","score":0.8330000042915344},{"id":"https://openalex.org/keywords/ct-guided-implantation","display_name":"CT-guided implantation","score":0.8410000205039978},{"id":"https://openalex.org/keywords/ultrasound-guided-implantation","display_name":"ultrasound-guided implantation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/local-control","display_name":"local control","score":0.8880000114440918},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.875},{"id":"https://openalex.org/keywords/post-radiotherapy-recurrence","display_name":"post-radiotherapy recurrence","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9055269956588745},{"id":"https://openalex.org/C136948725","wikidata":"https://www.wikidata.org/wiki/Q1458306","display_name":"Soft tissue","level":2,"score":0.7136813402175903},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.6689446568489075},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5974633693695068},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5786653757095337},{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.5244646072387695},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.4892148971557617},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.372127890586853}],"mesh":[{"descriptor_ui":"D000279","descriptor_name":"Administration, Cutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001918","descriptor_name":"Brachytherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D012983","descriptor_name":"Soft Tissue Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012983","descriptor_name":"Soft Tissue Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D012983","descriptor_name":"Soft Tissue Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016879","descriptor_name":"Salvage Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019018","descriptor_name":"Imagery, Psychotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1089/cbr.2010.0847","doi":"https://doi.org/10.1089/cbr.2010.0847","is_oa":false,"landing_page_url":"https://doi.org/10.1089/cbr.2010.0847","pdf_url":null,"source":{"id":"https://openalex.org/S87235987","display_name":"Cancer Biotherapy and Radiopharmaceuticals","issn_l":"1084-9785","issn":["1084-9785","1557-8852"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Biotherapy and Radiopharmaceuticals","raw_type":"journal-article"},{"id":"pmid:21355782","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21355782","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer biotherapy & radiopharmaceuticals","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1878715328","https://openalex.org/W1971615209","https://openalex.org/W1972389992","https://openalex.org/W1981877858","https://openalex.org/W1984301456","https://openalex.org/W1994454605","https://openalex.org/W2001055055","https://openalex.org/W2004035361","https://openalex.org/W2004809757","https://openalex.org/W2005969760","https://openalex.org/W2010973764","https://openalex.org/W2021969695","https://openalex.org/W2023288297","https://openalex.org/W2032803160","https://openalex.org/W2035214384","https://openalex.org/W2038506441","https://openalex.org/W2039808819","https://openalex.org/W2043945205","https://openalex.org/W2044437544","https://openalex.org/W2044899594","https://openalex.org/W2050501712","https://openalex.org/W2062008907","https://openalex.org/W2066817268","https://openalex.org/W2084903199","https://openalex.org/W2094444578","https://openalex.org/W2097832473","https://openalex.org/W2106224027","https://openalex.org/W2120496788","https://openalex.org/W2130519973","https://openalex.org/W2141061701","https://openalex.org/W2142543132","https://openalex.org/W2146215521","https://openalex.org/W2167805334","https://openalex.org/W2209895325","https://openalex.org/W2315866088"],"related_works":["https://openalex.org/W2888635749","https://openalex.org/W2974880639","https://openalex.org/W2213114099","https://openalex.org/W2292645613","https://openalex.org/W2972932052","https://openalex.org/W2018786865","https://openalex.org/W4221080301","https://openalex.org/W1997834479","https://openalex.org/W2981503202","https://openalex.org/W1966323905"],"abstract_inverted_index":{"The":[0,57,87,112,123,140,150],"purpose":[1],"of":[2,12,28,61,73,89,181,187,204],"this":[3],"study":[4],"was":[5,65,116,143],"to":[6,40,81,95,106,207],"evaluate":[7],"the":[8,26,70,74,90,205],"safety":[9],"and":[10,35,69,128,137,156,164,184,199,225,231],"efficacy":[11,230],"percutaneous":[13],"iodine-125":[14],"((125)I)":[15],"seed":[16,174,211],"implantation":[17,212],"using":[18],"computed":[19],"tomography":[20],"(CT)":[21],"or":[22,54,220],"ultrasound":[23,53,221],"guidance":[24,222],"in":[25],"treatment":[27],"recurrent":[29,46,214],"soft":[30,47,215],"tissue":[31,48,216],"malignancies":[32,217],"after":[33,173],"surgery":[34],"radiotherapy.":[36],"From":[37],"February":[38],"2002":[39],"September":[41],"2009,":[42],"18":[43],"patients":[44,169,178,191],"with":[45,228],"sarcomas":[49],"were":[50,132,159],"treated":[51],"under":[52,218],"CT":[55,219],"guidance.":[56],"actuarial":[58,71,151],"median":[59,113,141],"number":[60],"(125)I":[62,76,210],"seeds":[63,77,91],"implanted":[64,75],"35":[66],"(range,":[67],"6-129),":[68],"D90":[72],"ranged":[78,92,103],"from":[79,93,104],"107.9":[80],"204.4":[82],"Gy":[83],"(median,":[84,98,109],"147.1":[85],"Gy).":[86],"activity":[88],"0.4":[94],"0.8":[96],"mCi":[97],"0.7":[99],"mCi).":[100],"Follow-up":[101],"times":[102],"4":[105],"78":[107],"months":[108,118,145],"20":[110],"months).":[111,122,149],"local":[114,130],"control":[115],"41":[117],"(95%":[119,146],"CI,":[120,147],"15.9-66.1":[121],"1-,":[124,152],"2-,":[125,153],"3-,":[126,154],"4-,":[127,155],"5-year":[129,157],"controls":[131],"78.8%,":[133,134,135],"26.3%,":[136],"0%,":[138],"respectively.":[139,166],"survival":[142],"32":[144],"16-48":[148],"survivals":[158],"76.6%,":[160],"61.3%,":[161],"39.4%,":[162,163,165],"Seven":[167],"(7)":[168],"(38.9%)":[170],"experienced":[171],"recurrence":[172,198],"implantation.":[175],"Six":[176],"(6)":[177],"(33.3%)":[179],"died":[180,186],"distant":[182],"metastases":[183],"1":[185,194],"stroke.":[188],"Two":[189],"(2)":[190],"developed":[192],"ulceration,":[193],"case":[195],"caused":[196],"by":[197,201],"another":[200],"a":[202],"reaction":[203],"skin":[206],"radiation.":[208],"Percutaneous":[209],"for":[213],"is":[223,226],"safe":[224],"associated":[227],"high":[229],"low":[232],"morbidity.":[233]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}