{"id":"https://openalex.org/W1977798447","doi":"https://doi.org/10.1016/j.intimp.2014.07.019","title":"Combined immunotherapy with dendritic cells and cytokine-induced killer cells for malignant tumors: A systematic review and meta-analysis","display_name":"Combined immunotherapy with dendritic cells and cytokine-induced killer cells for malignant tumors: A systematic review and meta-analysis","publication_year":2014,"publication_date":"2014-07-27","ids":{"openalex":"https://openalex.org/W1977798447","doi":"https://doi.org/10.1016/j.intimp.2014.07.019","mag":"1977798447","pmid":"https://pubmed.ncbi.nlm.nih.gov/25073120"},"language":"en","primary_location":{"id":"doi:10.1016/j.intimp.2014.07.019","doi":"https://doi.org/10.1016/j.intimp.2014.07.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.intimp.2014.07.019","pdf_url":null,"source":{"id":"https://openalex.org/S158377717","display_name":"International Immunopharmacology","issn_l":"1567-5769","issn":["1567-5769","1878-1705"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Immunopharmacology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100400806","display_name":"Ran Chen","orcid":"https://orcid.org/0000-0002-8967-7258","observed_orcids":["https://orcid.org/0000-0002-8967-7258","https://orcid.org/0000-0002-2770-4070"]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran Chen","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China","institution_ids":["https://openalex.org/I4210113348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082330346","display_name":"Xin Deng","orcid":"https://orcid.org/0000-0002-1007-3794","observed_orcids":["https://orcid.org/0000-0002-1007-3794"]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xin Deng","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China. Electronic address: dx8848@126.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China. Electronic address: dx8848@126.com","institution_ids":["https://openalex.org/I4210113348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014474009","display_name":"Haochen Wu","orcid":"https://orcid.org/0009-0007-2682-5421","observed_orcids":["https://orcid.org/0009-0007-2682-5421"]},"institutions":[{"id":"https://openalex.org/I4210106687","display_name":"The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine","ror":"https://ror.org/01qh7se39","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106687"]},{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haochen Wu","raw_affiliation_strings":["Department of Hepatopathy, The First Affiliated Hospital of Guangxi, University of Chinese Medicine, Dongge Road No. 89-9, 530023 Nanning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatopathy, The First Affiliated Hospital of Guangxi, University of Chinese Medicine, Dongge Road No. 89-9, 530023 Nanning, China","institution_ids":["https://openalex.org/I4210106687","https://openalex.org/I4210113348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032924973","display_name":"Peichun Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peichun Peng","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China","institution_ids":["https://openalex.org/I4210113348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110032304","display_name":"Bin Wen","orcid":"https://orcid.org/0000-0003-4798-111X","observed_orcids":["https://orcid.org/0000-0003-4798-111X"]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Wen","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China","institution_ids":["https://openalex.org/I4210113348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109087272","display_name":"LI Fu-yin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuyin Li","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China","institution_ids":["https://openalex.org/I4210113348"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057894330","display_name":"Fenfen Li","orcid":"https://orcid.org/0000-0002-6456-5540","observed_orcids":["https://orcid.org/0000-0002-6456-5540"]},"institutions":[{"id":"https://openalex.org/I4210113348","display_name":"Guangxi University of Chinese Medicine","ror":"https://ror.org/024v0gx67","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113348"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fenfen Li","raw_affiliation_strings":["Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive, Ruikang Affiliated Hospital of Guangxi, University of Chinese Medicine, 530011 Huadong Road No. 10, Nanning, 530023 Guangxi, China","institution_ids":["https://openalex.org/I4210113348"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5082330346"],"corresponding_institution_ids":["https://openalex.org/I4210113348"],"apc_list":{"value":3220,"currency":"USD","value_usd":3220},"apc_paid":null,"fwci":0.4649,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.39536878,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"22","issue":"2","first_page":"451","last_page":"464"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dendritic-cell-immunotherapy","display_name":"dendritic cell immunotherapy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/cytokine-induced-killer-cells","display_name":"cytokine-induced killer cells","score":0.996999979019165},{"id":"https://openalex.org/keywords/adoptive-immunotherapy","display_name":"adoptive immunotherapy","score":0.8669999837875366},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.8700000047683716},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8320000171661377},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9869999885559082},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9639999866485596},{"id":"https://openalex.org/keywords/combination-chemotherapy","display_name":"combination chemotherapy","score":0.6110000014305115},{"id":"https://openalex.org/keywords/treatment-safety","display_name":"treatment safety","score":0.46799999475479126},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C2779109515","wikidata":"https://www.wikidata.org/wiki/Q18712057","display_name":"Cytokine-induced killer cell","level":5,"score":0.8682470321655273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.846542477607727},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6814162731170654},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6501855850219727},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6440482139587402},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6382185220718384},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.55311119556427},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.523271918296814},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5167726278305054},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.45858311653137207},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.44463682174682617},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.440314382314682},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3771785795688629},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3253176808357239},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1487993597984314},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.11895152926445007},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.06373262405395508},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.0},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055612","descriptor_name":"Cytokine-Induced Killer Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.intimp.2014.07.019","doi":"https://doi.org/10.1016/j.intimp.2014.07.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.intimp.2014.07.019","pdf_url":null,"source":{"id":"https://openalex.org/S158377717","display_name":"International Immunopharmacology","issn_l":"1567-5769","issn":["1567-5769","1878-1705"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Immunopharmacology","raw_type":"journal-article"},{"id":"pmid:25073120","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25073120","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International immunopharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W94447729","https://openalex.org/W138028528","https://openalex.org/W1481357784","https://openalex.org/W1530610894","https://openalex.org/W1661544713","https://openalex.org/W1968595366","https://openalex.org/W1971391314","https://openalex.org/W2001198480","https://openalex.org/W2010899054","https://openalex.org/W2012171870","https://openalex.org/W2021288842","https://openalex.org/W2028755894","https://openalex.org/W2030864103","https://openalex.org/W2039337673","https://openalex.org/W2050749285","https://openalex.org/W2059679895","https://openalex.org/W2077817785","https://openalex.org/W2079661342","https://openalex.org/W2079753662","https://openalex.org/W2082890828","https://openalex.org/W2091262320","https://openalex.org/W2101189819","https://openalex.org/W2104299555","https://openalex.org/W2123469465","https://openalex.org/W2133114658","https://openalex.org/W2140470079","https://openalex.org/W2145049340","https://openalex.org/W2148237316","https://openalex.org/W2150034934","https://openalex.org/W2170431359","https://openalex.org/W2177327503","https://openalex.org/W2183612735","https://openalex.org/W2253781563","https://openalex.org/W2291061047","https://openalex.org/W2300525339","https://openalex.org/W2352895600","https://openalex.org/W2361966667","https://openalex.org/W2363769595","https://openalex.org/W2365040960","https://openalex.org/W2365618040","https://openalex.org/W2381019473","https://openalex.org/W2383106836","https://openalex.org/W2387076140","https://openalex.org/W2387574820","https://openalex.org/W2390560129","https://openalex.org/W2393229852","https://openalex.org/W3098989474","https://openalex.org/W4249580611"],"related_works":["https://openalex.org/W2058362815","https://openalex.org/W4405641948","https://openalex.org/W2229874895","https://openalex.org/W833671764","https://openalex.org/W2377736174","https://openalex.org/W1965291896","https://openalex.org/W2389891277","https://openalex.org/W7098002774","https://openalex.org/W2383100813","https://openalex.org/W2393229852"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
