{"id":"https://openalex.org/W1977567422","doi":"https://doi.org/10.1016/j.biocel.2008.05.028","title":"HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors","display_name":"HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors","publication_year":2008,"publication_date":"2008-08-04","ids":{"openalex":"https://openalex.org/W1977567422","doi":"https://doi.org/10.1016/j.biocel.2008.05.028","mag":"1977567422","pmid":"https://pubmed.ncbi.nlm.nih.gov/18723112","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2631403"},"language":"en","primary_location":{"id":"doi:10.1016/j.biocel.2008.05.028","doi":"https://doi.org/10.1016/j.biocel.2008.05.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biocel.2008.05.028","pdf_url":null,"source":{"id":"https://openalex.org/S183320690","display_name":"The International Journal of Biochemistry & Cell Biology","issn_l":"1357-2725","issn":["1357-2725","1878-5875"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Biochemistry & Cell Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2631403","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084603190","display_name":"Capucine Van Rechem","orcid":"https://orcid.org/0000-0002-5408-6124","observed_orcids":["https://orcid.org/0000-0002-5408-6124"]},"institutions":[{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4387154560","display_name":"Universit\u00e9 Lille 1","ror":"https://ror.org/040hwdc70","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I4387154560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Capucine Fleuriel","raw_affiliation_strings":["Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 59017 Lille Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 59017 Lille Cedex, France","institution_ids":["https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4387154560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030940207","display_name":"Majid Touka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210163910","display_name":"Institut de Biologie de Lille","ror":"https://ror.org/05gd4yq49","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910"]},{"id":"https://openalex.org/I4387154560","display_name":"Universit\u00e9 Lille 1","ror":"https://ror.org/040hwdc70","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I4387154560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Majid Touka","raw_affiliation_strings":["CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910","https://openalex.org/I4387154560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044031119","display_name":"Gaylor Boulay","orcid":"https://orcid.org/0009-0001-7466-0760","observed_orcids":["https://orcid.org/0009-0001-7466-0760"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210163910","display_name":"Institut de Biologie de Lille","ror":"https://ror.org/05gd4yq49","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910"]},{"id":"https://openalex.org/I4387154560","display_name":"Universit\u00e9 Lille 1","ror":"https://ror.org/040hwdc70","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I4387154560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gaylor Boulay","raw_affiliation_strings":["CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910","https://openalex.org/I4387154560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074517297","display_name":"Cateline Gu\u00e9rardel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210163910","display_name":"Institut de Biologie de Lille","ror":"https://ror.org/05gd4yq49","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910"]},{"id":"https://openalex.org/I4387154560","display_name":"Universit\u00e9 Lille 1","ror":"https://ror.org/040hwdc70","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I4387154560"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cateline Gu\u00e9rardel","raw_affiliation_strings":["CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910","https://openalex.org/I4387154560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088213305","display_name":"Brian R. Rood","orcid":"https://orcid.org/0000-0003-3221-9421","observed_orcids":["https://orcid.org/0000-0003-3221-9421"]},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian R. Rood","raw_affiliation_strings":["Children's National Medical Center, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's National Medical Center, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063650567","display_name":"Dominique Leprince","orcid":"https://orcid.org/0000-0002-1999-0775","observed_orcids":["https://orcid.org/0000-0002-1999-0775"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I2800921988","display_name":"Institut Pasteur de Lille","ror":"https://ror.org/05k9skc85","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2800921988"]},{"id":"https://openalex.org/I4210163910","display_name":"Institut de Biologie de Lille","ror":"https://ror.org/05gd4yq49","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910"]},{"id":"https://openalex.org/I4387154560","display_name":"Universit\u00e9 Lille 1","ror":"https://ror.org/040hwdc70","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970","https://openalex.org/I4387154560"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Dominique Leprince","raw_affiliation_strings":["CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS UMR 8161 \u00abInstitut de Biologie de LILLE\u00bb, CNRS, Universit\u00e9 de Lille 1 et de Lille 2, Institut PASTEUR de LILLE, 1 Rue Calmette, BP 447, 59017 Lille Cedex, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910","https://openalex.org/I4387154560"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5063650567"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2279609970","https://openalex.org/I2800921988","https://openalex.org/I4210163910","https://openalex.org/I4387154560"],"apc_list":{"value":3840,"currency":"USD","value_usd":3840},"apc_paid":null,"fwci":0.5236,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.42517344,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"41","issue":"1","first_page":"26","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hic1","display_name":"HIC1","score":0.996999979019165},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.7170000076293945},{"id":"https://openalex.org/keywords/epigenetic-silencing","display_name":"epigenetic silencing","score":0.878000020980835},{"id":"https://openalex.org/keywords/dna-hypermethylation","display_name":"DNA hypermethylation","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cpg-islands","display_name":"CpG islands","score":0.8069999814033508},{"id":"https://openalex.org/keywords/17p13-3","display_name":"17p13.3","score":0.8709999918937683},{"id":"https://openalex.org/keywords/zinc-finger-transcription-factor","display_name":"zinc finger transcription factor","score":0.8230000138282776},{"id":"https://openalex.org/keywords/btb-poz-domain","display_name":"BTB/POZ domain","score":0.8759999871253967},{"id":"https://openalex.org/keywords/corepressor-complex","display_name":"corepressor complex","score":0.8140000104904175},{"id":"https://openalex.org/keywords/histone-deacetylase","display_name":"histone deacetylase","score":0.8960000276565552},{"id":"https://openalex.org/keywords/loss-of-heterozygosity","display_name":"loss of heterozygosity","score":0.9279999732971191},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.9210000038146973},{"id":"https://openalex.org/keywords/sirt1","display_name":"SIRT1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.704011082649231},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7001047134399414},{"id":"https://openalex.org/C146777309","wikidata":"https://www.wikidata.org/wiki/Q1132599","display_name":"Corepressor","level":5,"score":0.6467509269714355},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5852342844009399},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5270686149597168},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5069899559020996},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.5040380358695984},{"id":"https://openalex.org/C24284526","wikidata":"https://www.wikidata.org/wiki/Q204785","display_name":"Zinc finger","level":4,"score":0.4769279360771179},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.4713693857192993},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4596637487411499},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4428649842739105},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.41910409927368164},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.40735045075416565},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1782042384147644}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006579","descriptor_name":"Heterozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006655","descriptor_name":"Histone Deacetylases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016335","descriptor_name":"Zinc Fingers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020868","descriptor_name":"Gene Silencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037761","descriptor_name":"Sirtuins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037761","descriptor_name":"Sirtuins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051741","descriptor_name":"Kruppel-Like Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051741","descriptor_name":"Kruppel-Like Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.biocel.2008.05.028","doi":"https://doi.org/10.1016/j.biocel.2008.05.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biocel.2008.05.028","pdf_url":null,"source":{"id":"https://openalex.org/S183320690","display_name":"The International Journal of Biochemistry & Cell Biology","issn_l":"1357-2725","issn":["1357-2725","1878-5875"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The International Journal of Biochemistry & Cell Biology","raw_type":"journal-article"},{"id":"pmid:18723112","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18723112","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The international journal of biochemistry & cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:1662692","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2631403","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2631403","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2631403","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Int J Biochem Cell Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1662692","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2631403","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6743644354","display_name":"Creation of a PDGF-C Autocrine Loop by HIC1 Inactivation","funder_award_id":"K08NS051477","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320322363","display_name":"Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W95252060","https://openalex.org/W1549718605","https://openalex.org/W1552282019","https://openalex.org/W1558473757","https://openalex.org/W1559854301","https://openalex.org/W1572433661","https://openalex.org/W1655320805","https://openalex.org/W1718183980","https://openalex.org/W1744223828","https://openalex.org/W1831451634","https://openalex.org/W1966971933","https://openalex.org/W1968728947","https://openalex.org/W1969600675","https://openalex.org/W1969670934","https://openalex.org/W1976360812","https://openalex.org/W1978686575","https://openalex.org/W1979935374","https://openalex.org/W1982529039","https://openalex.org/W1983341583","https://openalex.org/W1985902016","https://openalex.org/W1988631133","https://openalex.org/W1990120418","https://openalex.org/W1990362235","https://openalex.org/W2003750107","https://openalex.org/W2010894705","https://openalex.org/W2013108773","https://openalex.org/W2019432938","https://openalex.org/W2029868343","https://openalex.org/W2031221239","https://openalex.org/W2033668038","https://openalex.org/W2040626587","https://openalex.org/W2041480426","https://openalex.org/W2042087070","https://openalex.org/W2042911870","https://openalex.org/W2044702738","https://openalex.org/W2044784487","https://openalex.org/W2047078030","https://openalex.org/W2050022931","https://openalex.org/W2052543236","https://openalex.org/W2056453168","https://openalex.org/W2065292885","https://openalex.org/W2067991344","https://openalex.org/W2075712243","https://openalex.org/W2078406365","https://openalex.org/W2089456640","https://openalex.org/W2092098054","https://openalex.org/W2093587470","https://openalex.org/W2100534395","https://openalex.org/W2100566978","https://openalex.org/W2101690600","https://openalex.org/W2112789122","https://openalex.org/W2119280406","https://openalex.org/W2123283129","https://openalex.org/W2123924669","https://openalex.org/W2124181024","https://openalex.org/W2126809688","https://openalex.org/W2131922441","https://openalex.org/W2137724755","https://openalex.org/W2141410747","https://openalex.org/W2143530087","https://openalex.org/W2146495496","https://openalex.org/W2147977885","https://openalex.org/W2150710841","https://openalex.org/W2152025793","https://openalex.org/W2152763796","https://openalex.org/W2153424791","https://openalex.org/W2153598858","https://openalex.org/W2155972116","https://openalex.org/W2159480680","https://openalex.org/W2159956236","https://openalex.org/W2161235273","https://openalex.org/W2164786397","https://openalex.org/W2168289490","https://openalex.org/W2170210082","https://openalex.org/W2321722406","https://openalex.org/W2333126945","https://openalex.org/W2412410165","https://openalex.org/W2415724633","https://openalex.org/W6633452741","https://openalex.org/W6634338709","https://openalex.org/W6637180022","https://openalex.org/W6637382835","https://openalex.org/W6642375900","https://openalex.org/W6678192862","https://openalex.org/W6678531577","https://openalex.org/W6682109128","https://openalex.org/W6716424943"],"related_works":["https://openalex.org/W2075936770","https://openalex.org/W2115609857","https://openalex.org/W2019733062","https://openalex.org/W2736731596","https://openalex.org/W2089456640","https://openalex.org/W3032658092","https://openalex.org/W1966971933","https://openalex.org/W7212057067","https://openalex.org/W2490840188","https://openalex.org/W2012119981"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}