{"id":"https://openalex.org/W1977401341","doi":null,"title":"Population based study of risk factors for underdiagnosis of asthma in adolescence: Odense schoolchild study.","display_name":"Population based study of risk factors for underdiagnosis of asthma in adolescence: Odense schoolchild study.","publication_year":1998,"publication_date":"1998-02-28","ids":{"openalex":"https://openalex.org/W1977401341","mag":"1977401341","pmid":"https://pubmed.ncbi.nlm.nih.gov/9522784","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:1800259","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103375398","display_name":"Hans Christian Siersted","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"H C Siersted","raw_affiliation_strings":["Department of Medicine C, Odense University Hospital, Denmark. hc.siersted@winsloew.ou.dk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine C, Odense University Hospital, Denmark. hc.siersted@winsloew.ou.dk","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078854560","display_name":"Jesper L. Boldsen","orcid":"https://orcid.org/0000-0002-2850-0934","observed_orcids":["https://orcid.org/0000-0002-2850-0934"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Boldsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118899780","display_name":"Henrik Steen Hansen","orcid":"https://orcid.org/0000-0001-6477-9832","observed_orcids":["https://orcid.org/0000-0001-6477-9832"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H S Hansen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015137010","display_name":"G. Mostgaard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Mostgaard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5048094348","display_name":"Niels Hyldebrandt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Hyldebrandt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.7687,"has_fulltext":false,"cited_by_count":182,"citation_normalized_percentile":{"value":0.97038611,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"316","issue":"7132","first_page":"651","last_page":"5; discussion 655"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma-underdiagnosis","display_name":"asthma underdiagnosis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/adolescent-asthma","display_name":"adolescent asthma","score":0.8539999723434448},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.8899999856948853},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.8169999718666077},{"id":"https://openalex.org/keywords/body-mass","display_name":"body mass","score":0.8169999718666077},{"id":"https://openalex.org/keywords/family-problems","display_name":"family problems","score":0.9779999852180481},{"id":"https://openalex.org/keywords/passive-smoking","display_name":"passive smoking","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rhinitis","display_name":"rhinitis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8360000252723694},{"id":"https://openalex.org/keywords/symptom-reporting","display_name":"symptom reporting","score":0.843999981880188},{"id":"https://openalex.org/keywords/cough","display_name":"cough","score":0.5130000114440918},{"id":"https://openalex.org/keywords/wheezing","display_name":"wheezing","score":0.8019999861717224},{"id":"https://openalex.org/keywords/airway-hyperresponsiveness","display_name":"airway hyperresponsiveness","score":0.7789999842643738},{"id":"https://openalex.org/keywords/peak-expiratory-flow-variability","display_name":"peak expiratory flow variability","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.8872944116592407},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8755732178688049},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.6549052596092224},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5679616332054138},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5675890445709229},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5470848083496094},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.48916295170783997},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.47658535838127136},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4258272051811218},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.35387158393859863},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23529675602912903},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09283557534217834},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.07033100724220276}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003718","descriptor_name":"Denmark","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012129","descriptor_name":"Respiratory Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012135","descriptor_name":"Respiratory Sounds","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014028","descriptor_name":"Tobacco Smoke Pollution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017678","descriptor_name":"Sex Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:1800259","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:28467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ","raw_type":"Text"},{"id":"pmid:9522784","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9522784","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ (Clinical research ed.)","raw_type":"Journal Article"},{"id":"mag:1977401341","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9522784","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1800259","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28467","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W62352407","https://openalex.org/W410068482","https://openalex.org/W587155859","https://openalex.org/W1886531014","https://openalex.org/W1964026344","https://openalex.org/W1964784191","https://openalex.org/W1969465774","https://openalex.org/W1975593062","https://openalex.org/W1981046402","https://openalex.org/W1985059597","https://openalex.org/W1994935987","https://openalex.org/W2009122263","https://openalex.org/W2011932878","https://openalex.org/W2012298731","https://openalex.org/W2014468450","https://openalex.org/W2019280107","https://openalex.org/W2024471274","https://openalex.org/W2028915082","https://openalex.org/W2034909797","https://openalex.org/W2041223278","https://openalex.org/W2041533148","https://openalex.org/W2050396149","https://openalex.org/W2061612689","https://openalex.org/W2064372203","https://openalex.org/W2068220762","https://openalex.org/W2072394348","https://openalex.org/W2086394533","https://openalex.org/W2090529413","https://openalex.org/W2091506389","https://openalex.org/W2106245415","https://openalex.org/W2109059311","https://openalex.org/W2116494380","https://openalex.org/W2117273521","https://openalex.org/W2119208669","https://openalex.org/W2123247260","https://openalex.org/W2133247949","https://openalex.org/W2135307447","https://openalex.org/W2138833640","https://openalex.org/W2140873758","https://openalex.org/W2146237101","https://openalex.org/W2157604999","https://openalex.org/W2161209070","https://openalex.org/W2162103288","https://openalex.org/W2165586667","https://openalex.org/W2298760082","https://openalex.org/W2329387762","https://openalex.org/W2337807480","https://openalex.org/W2403313877","https://openalex.org/W2412583831","https://openalex.org/W4285719527","https://openalex.org/W4300568747"],"related_works":["https://openalex.org/W4289919666","https://openalex.org/W4244714652","https://openalex.org/W2019280107","https://openalex.org/W4210867891","https://openalex.org/W2017713718","https://openalex.org/W2908811614","https://openalex.org/W2970586544","https://openalex.org/W2091532294","https://openalex.org/W2918637414","https://openalex.org/W2262401927"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"describe":[2],"factors":[3,116,171,261],"related":[4],"to":[5,29,95,100,222,253],"underdiagnosis":[6],"of":[7,37,76,88,111,128,151,215,266],"asthma":[8,72,123,130,160],"in":[9,14,61,92,108,178],"adolescence.":[10],"DESIGN:":[11],"Subgroup":[12],"analysis":[13],"a":[15,35,54,223,250],"population":[16],"based":[17],"cohort":[18,36],"study.":[19],"SETTING:":[20],"Odense":[21],"municipality,":[22],"Denmark.":[23],"SUBJECTS:":[24],"495":[25],"schoolchildren":[26],"aged":[27],"12":[28],"15":[30],"years":[31,42],"were":[32,154,181],"selected":[33],"from":[34],"1369":[38],"children":[39],"investigated":[40],"3":[41],"earlier.":[43],"Selection":[44],"was":[45,133,193,203,235,241,247],"done":[46],"by":[47,53,229],"randomisation":[48],"(n":[49,65],"=":[50,66],"292)":[51],"and":[52,79,148,162,176,232,246,256],"history":[55],"indicating":[56],"allergy":[57],"or":[58,63,81,102,104,199],"asthma-like":[59,77],"symptoms":[60,78,221,231,255],"subject":[62],"family":[64,144,180],"203).":[67],"MAIN":[68],"OUTCOME":[69],"MEASURES:":[70],"Undiagnosed":[71,122],"defined":[73,228],"as":[74,227],"coexistence":[75],"one":[80,126,213],"more":[82],"obstructive":[83],"airway":[84],"abnormalities":[85],"(low":[86],"ratio":[87],"forced":[89,96],"expiratory":[90],"volume":[91],"1":[93],"second":[94],"vital":[97],"capacity,":[98],"hyperresponsiveness":[99],"methacholine":[101],"exercise,":[103],"peak":[105],"flow":[106],"hypervariability)":[107],"the":[109,149,169,179],"absence":[110,150],"physician":[112],"diagnosed":[113,165],"asthma.":[114],"Risk":[115],"(odds":[117],"ratios)":[118],"for":[119],"underdiagnosis.":[120],"RESULTS:":[121],"comprised":[124],"about":[125],"third":[127,214],"all":[129],"identified.":[131],"Underdiagnosis":[132,240],"independently":[134,182],"associated":[135,183,248],"with":[136,159,184,249,257],"low":[137,173,251],"physical":[138,174],"activity,":[139],"high":[140],"body":[141],"mass,":[142],"serious":[143],"problems,":[145],"passive":[146],"smoking,":[147],"rhinitis.":[152],"Girls":[153],"overrepresented":[155],"among":[156,164,190,208,238,244],"undiagnosed":[157,192,217,268],"patients":[158,166],"(69%)":[161],"underrepresented":[163],"(33%).":[167],"Among":[168],"risk":[170,260],"identified,":[172],"activity":[175],"problems":[177],"female":[185],"sex.":[186],"The":[187],"major":[188],"symptom":[189],"those":[191,209,216],"cough":[194],"(58%),":[195],"whereas":[196],"wheezing":[197],"(35%)":[198],"breathing":[200],"trouble":[201],"(50%)":[202],"reported":[204,219],"less":[205],"frequently":[206],"than":[207,212],"diagnosed.":[210],"Less":[211],"had":[218],"their":[220],"doctor.":[224],"CONCLUSIONS:":[225],"Asthma,":[226],"combined":[230],"test":[233],"criteria,":[234],"seriously":[236],"underdiagnosed":[237],"adolescents.":[239],"most":[242],"prevalent":[243],"girls":[245],"tendency":[252],"report":[254],"several":[258],"independent":[259],"that":[262],"may":[263],"help":[264],"identification":[265],"previously":[267],"asthmatic":[269],"patients.":[270]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}