{"id":"https://openalex.org/W1977346307","doi":"https://doi.org/10.1006/dbio.2000.9609","title":"Snail-Related Transcriptional Repressors Are Required in Xenopus for both the Induction of the Neural Crest and Its Subsequent Migration","display_name":"Snail-Related Transcriptional Repressors Are Required in Xenopus for both the Induction of the Neural Crest and Its Subsequent Migration","publication_year":2000,"publication_date":"2000-05-01","ids":{"openalex":"https://openalex.org/W1977346307","doi":"https://doi.org/10.1006/dbio.2000.9609","mag":"1977346307","pmid":"https://pubmed.ncbi.nlm.nih.gov/10772801"},"language":"en","primary_location":{"id":"doi:10.1006/dbio.2000.9609","doi":"https://doi.org/10.1006/dbio.2000.9609","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9609","pdf_url":"https://www.sciencedirect.com/science/article/pii/S001216060099609X/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1977346307"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S001216060099609X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002805838","display_name":"Carole LaBonne","orcid":"https://orcid.org/0000-0001-6001-7179","observed_orcids":["https://orcid.org/0000-0001-6001-7179"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"C. LaBonne","raw_affiliation_strings":["Division of Biology 139-74, California Institute of Technology, Pasadena, California 91125, USA. clabonne@caltech.edu","Division of Biology, 139-74, California Institute of Technology, Pasadena, California 91125 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology 139-74, California Institute of Technology, Pasadena, California 91125, USA. clabonne@caltech.edu","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Division of Biology, 139-74, California Institute of Technology, Pasadena, California 91125 USA","institution_ids":["https://openalex.org/I122411786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019521298","display_name":"Marianne E. Bronner-Fraser","orcid":"https://orcid.org/0000-0003-4274-1862","observed_orcids":["https://orcid.org/0000-0003-4274-1862"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Bronner-Fraser","raw_affiliation_strings":["Division of Biology 139-74, California Institute of Technology, Pasadena, California, 91125"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology 139-74, California Institute of Technology, Pasadena, California, 91125","institution_ids":["https://openalex.org/I122411786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002805838"],"corresponding_institution_ids":["https://openalex.org/I122411786"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":5.3748,"has_fulltext":true,"cited_by_count":261,"citation_normalized_percentile":{"value":0.96991751,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"221","issue":"1","first_page":"195","last_page":"205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neural-crest","display_name":"neural crest","score":0.8389999866485596},{"id":"https://openalex.org/keywords/neural-crest-migration","display_name":"neural crest migration","score":0.7350000143051147},{"id":"https://openalex.org/keywords/snail-transcription-factor","display_name":"Snail transcription factor","score":0.6949999928474426},{"id":"https://openalex.org/keywords/transcriptional-repressor","display_name":"transcriptional repressor","score":0.7799999713897705},{"id":"https://openalex.org/keywords/zinc-finger-transcription-factor","display_name":"zinc finger transcription factor","score":0.8569999933242798},{"id":"https://openalex.org/keywords/melanocyte-differentiation","display_name":"melanocyte differentiation","score":0.6620000004768372},{"id":"https://openalex.org/keywords/xenopus-embryo","display_name":"Xenopus embryo","score":0.8679999709129333},{"id":"https://openalex.org/keywords/neural-crest-induction","display_name":"neural crest induction","score":0.5910000205039978}],"concepts":[{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.9168645739555359},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8901435136795044},{"id":"https://openalex.org/C64632358","wikidata":"https://www.wikidata.org/wiki/Q95351881","display_name":"engrailed","level":5,"score":0.7518028020858765},{"id":"https://openalex.org/C197849852","wikidata":"https://www.wikidata.org/wiki/Q2314823","display_name":"Neural plate","level":4,"score":0.7080487608909607},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.6803785562515259},{"id":"https://openalex.org/C103607123","wikidata":"https://www.wikidata.org/wiki/Q7002059","display_name":"Neural fold","level":5,"score":0.6643180847167969},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6103561520576477},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4950651228427887},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4523981809616089},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.4390822947025299},{"id":"https://openalex.org/C2779535977","wikidata":"https://www.wikidata.org/wiki/Q1342298","display_name":"Xenopus","level":3,"score":0.4363630712032318},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.41779613494873047},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24248668551445007},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.21449002623558044},{"id":"https://openalex.org/C121587040","wikidata":"https://www.wikidata.org/wiki/Q898769","display_name":"Homeobox","level":4,"score":0.1125703752040863}],"mesh":[{"descriptor_ui":"D000071250","descriptor_name":"Snail Family Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008164","descriptor_name":"Luminescent Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008845","descriptor_name":"Microinjections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014981","descriptor_name":"Xenopus","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D017403","descriptor_name":"In Situ Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049452","descriptor_name":"Green Fluorescent Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1006/dbio.2000.9609","doi":"https://doi.org/10.1006/dbio.2000.9609","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9609","pdf_url":"https://www.sciencedirect.com/science/article/pii/S001216060099609X/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmid:10772801","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10772801","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental biology","raw_type":"Journal Article"},{"id":"pmh:oai:authors.library.caltech.edu:65262","doi":null,"is_oa":false,"landing_page_url":"https://resolver.caltech.edu/CaltechAUTHORS:20160310-123654012","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1006/dbio.2000.9609","doi":"https://doi.org/10.1006/dbio.2000.9609","is_oa":true,"landing_page_url":"https://doi.org/10.1006/dbio.2000.9609","pdf_url":"https://www.sciencedirect.com/science/article/pii/S001216060099609X/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3501577250","display_name":null,"funder_award_id":"NS36585","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G361822350","display_name":null,"funder_award_id":"NS34671","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G5571366709","display_name":"REGULATIVE ABILITY OF THE CRANIAL NEURAL TUBE","funder_award_id":"R01NS034671","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G957981624","display_name":null,"funder_award_id":"NS 36585","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320306095","display_name":"American Cancer Society","ror":"https://ror.org/02e463172"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320338075","display_name":"Core Research for Evolutional Science and Technology","ror":"https://ror.org/00097mb19"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1977346307.pdf","grobid_xml":"https://content.openalex.org/works/W1977346307.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W638406814","https://openalex.org/W1565566882","https://openalex.org/W1620478163","https://openalex.org/W1911954838","https://openalex.org/W1952870715","https://openalex.org/W1965940794","https://openalex.org/W1985721503","https://openalex.org/W2005302341","https://openalex.org/W2006417453","https://openalex.org/W2025790672","https://openalex.org/W2033509429","https://openalex.org/W2037397876","https://openalex.org/W2045594625","https://openalex.org/W2052459095","https://openalex.org/W2053054224","https://openalex.org/W2053504519","https://openalex.org/W2064387879","https://openalex.org/W2066021890","https://openalex.org/W2076657501","https://openalex.org/W2081424815","https://openalex.org/W2086519742","https://openalex.org/W2092911887","https://openalex.org/W2108186158","https://openalex.org/W2137280750","https://openalex.org/W2141516235","https://openalex.org/W2148524869","https://openalex.org/W2151240250","https://openalex.org/W2152893516","https://openalex.org/W2158071345","https://openalex.org/W2187716738","https://openalex.org/W2396111405","https://openalex.org/W2416447723","https://openalex.org/W2798301659"],"related_works":["https://openalex.org/W2027059131","https://openalex.org/W2108186158","https://openalex.org/W2151812223","https://openalex.org/W2113558048","https://openalex.org/W1911954838","https://openalex.org/W1976904496","https://openalex.org/W2162362760","https://openalex.org/W2088568448","https://openalex.org/W2079504814"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}