{"id":"https://openalex.org/W1977200430","doi":"https://doi.org/10.1016/j.chemosphere.2007.11.031","title":"ROS and CDPK-like kinase-mediated activation of MAP kinase in rice roots exposed to lead","display_name":"ROS and CDPK-like kinase-mediated activation of MAP kinase in rice roots exposed to lead","publication_year":2008,"publication_date":"2008-01-02","ids":{"openalex":"https://openalex.org/W1977200430","doi":"https://doi.org/10.1016/j.chemosphere.2007.11.031","mag":"1977200430","pmid":"https://pubmed.ncbi.nlm.nih.gov/18164745"},"language":"en","primary_location":{"id":"doi:10.1016/j.chemosphere.2007.11.031","doi":"https://doi.org/10.1016/j.chemosphere.2007.11.031","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.chemosphere.2007.11.031","pdf_url":null,"source":{"id":"https://openalex.org/S203465130","display_name":"Chemosphere","issn_l":"0045-6535","issn":["0045-6535","1879-1298"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemosphere","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110089265","display_name":"Tsai\u2010Lien Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tsai-Lien Huang","raw_affiliation_strings":["Department of Life Sciences, National Cheng Kung University, No. 1 University Road 701, Tainan, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, National Cheng Kung University, No. 1 University Road 701, Tainan, Taiwan, ROC","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108439046","display_name":"Hao-Jen Huang","orcid":"https://orcid.org/0000-0002-7459-162X","observed_orcids":["https://orcid.org/0000-0002-7459-162X","https://orcid.org/0009-0000-5577-8512"]},"institutions":[{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Hao-Jen Huang","raw_affiliation_strings":["Department of Life Sciences, National Cheng Kung University, No. 1 University Road 701, Tainan, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, National Cheng Kung University, No. 1 University Road 701, Tainan, Taiwan, ROC","institution_ids":["https://openalex.org/I91807558"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108439046"],"corresponding_institution_ids":["https://openalex.org/I91807558"],"apc_list":{"value":4010,"currency":"USD","value_usd":4010},"apc_paid":null,"fwci":4.9227,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.94131287,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"71","issue":"7","first_page":"1377","last_page":"1385"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12211","display_name":"Aluminum toxicity and tolerance in plants and animals","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10139","display_name":"Heavy metals in environment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lead-toxicity","display_name":"lead toxicity","score":0.9779999852180481},{"id":"https://openalex.org/keywords/rice-roots","display_name":"rice roots","score":0.9039999842643738},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9929999709129333},{"id":"https://openalex.org/keywords/calcium-dependent-protein-kinase","display_name":"calcium-dependent protein kinase","score":0.9750000238418579},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.8019999861717224},{"id":"https://openalex.org/keywords/myelin-basic-protein-kinase","display_name":"myelin basic protein kinase","score":0.9279999732971191},{"id":"https://openalex.org/keywords/calcium-accumulation","display_name":"calcium accumulation","score":0.6549999713897705},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7310000061988831},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.6840000152587891},{"id":"https://openalex.org/keywords/diphenyleneiodonium","display_name":"diphenyleneiodonium","score":0.9890000224113464},{"id":"https://openalex.org/keywords/w-7","display_name":"W-7","score":0.5550000071525574},{"id":"https://openalex.org/keywords/cell-death","display_name":"cell death","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.6990779042243958},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.5901764035224915},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5837146639823914},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.5529362559318542},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4934157431125641},{"id":"https://openalex.org/C2779719074","wikidata":"https://www.wikidata.org/wiki/Q2038057","display_name":"NADPH oxidase","level":3,"score":0.492118775844574},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.472688227891922},{"id":"https://openalex.org/C132149769","wikidata":"https://www.wikidata.org/wiki/Q899651","display_name":"Mitogen-activated protein kinase","level":3,"score":0.43820804357528687},{"id":"https://openalex.org/C124160383","wikidata":"https://www.wikidata.org/wiki/Q14914383","display_name":"ASK1","level":5,"score":0.43805426359176636},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.42069047689437866},{"id":"https://openalex.org/C90934575","wikidata":"https://www.wikidata.org/wiki/Q6593810","display_name":"Mitogen-activated protein kinase kinase","level":4,"score":0.385659784078598},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35894840955734253},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34803012013435364},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.28095901012420654},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.11012318730354309},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08745867013931274}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004785","descriptor_name":"Environmental Pollutants","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004785","descriptor_name":"Environmental Pollutants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D007854","descriptor_name":"Lead","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007854","descriptor_name":"Lead","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017871","descriptor_name":"Calcium-Calmodulin-Dependent Protein Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020928","descriptor_name":"Mitogen-Activated Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.chemosphere.2007.11.031","doi":"https://doi.org/10.1016/j.chemosphere.2007.11.031","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.chemosphere.2007.11.031","pdf_url":null,"source":{"id":"https://openalex.org/S203465130","display_name":"Chemosphere","issn_l":"0045-6535","issn":["0045-6535","1879-1298"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemosphere","raw_type":"journal-article"},{"id":"pmid:18164745","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18164745","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemosphere","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W32872513","https://openalex.org/W1490434835","https://openalex.org/W1534005684","https://openalex.org/W1586582258","https://openalex.org/W1968666258","https://openalex.org/W1975675866","https://openalex.org/W1988563290","https://openalex.org/W1990213589","https://openalex.org/W1993816077","https://openalex.org/W2018776706","https://openalex.org/W2021070427","https://openalex.org/W2022650336","https://openalex.org/W2024172986","https://openalex.org/W2026552295","https://openalex.org/W2029203863","https://openalex.org/W2029943774","https://openalex.org/W2040941625","https://openalex.org/W2042689385","https://openalex.org/W2050383118","https://openalex.org/W2062216055","https://openalex.org/W2075648225","https://openalex.org/W2088728566","https://openalex.org/W2089691429","https://openalex.org/W2093539102","https://openalex.org/W2096932204","https://openalex.org/W2119326646","https://openalex.org/W2123047746","https://openalex.org/W2126595031","https://openalex.org/W2132513174","https://openalex.org/W2137904897","https://openalex.org/W2139202993","https://openalex.org/W2158508949","https://openalex.org/W2167539266","https://openalex.org/W2328643786","https://openalex.org/W2410624855","https://openalex.org/W3047338879","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2137904897","https://openalex.org/W2123047746","https://openalex.org/W2953820967","https://openalex.org/W2088608872","https://openalex.org/W1997781269","https://openalex.org/W1975675866","https://openalex.org/W2042245748","https://openalex.org/W2047517568","https://openalex.org/W2126595031","https://openalex.org/W2001173363"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}