{"id":"https://openalex.org/W1977150223","doi":"https://doi.org/10.1021/ol900667g","title":"Highly Enantioselective Catalytic Alkyl Propiolate Addition to Aliphatic Aldehydes","display_name":"Highly Enantioselective Catalytic Alkyl Propiolate Addition to Aliphatic Aldehydes","publication_year":2009,"publication_date":"2009-05-07","ids":{"openalex":"https://openalex.org/W1977150223","doi":"https://doi.org/10.1021/ol900667g","mag":"1977150223","pmid":"https://pubmed.ncbi.nlm.nih.gov/19422198"},"language":"en","primary_location":{"id":"doi:10.1021/ol900667g","doi":"https://doi.org/10.1021/ol900667g","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ol900667g","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066861117","display_name":"Mark Turlington","orcid":"https://orcid.org/0000-0002-6126-0119","observed_orcids":["https://orcid.org/0000-0002-6126-0119"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Turlington","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048819570","display_name":"Albert M. DeBerardinis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert M. DeBerardinis","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031341127","display_name":"Lin Pu","orcid":"https://orcid.org/0000-0001-8698-3228","observed_orcids":["https://orcid.org/0000-0001-8698-3228"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lin Pu","raw_affiliation_strings":["Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904-4319","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031341127"],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":3.3861,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.91956794,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"11","issue":"11","first_page":"2441","last_page":"2444"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11281","display_name":"Asymmetric Hydrogenation and Catalysis","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13115","display_name":"Axial and Atropisomeric Chirality Synthesis","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aliphatic-aldehydes","display_name":"aliphatic aldehydes","score":0.9679999947547913},{"id":"https://openalex.org/keywords/asymmetric-catalysis","display_name":"asymmetric catalysis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/zinc-ethoxide","display_name":"zinc ethoxide","score":0.49900001287460327},{"id":"https://openalex.org/keywords/titanium-isopropoxide","display_name":"titanium isopropoxide","score":0.8349999785423279},{"id":"https://openalex.org/keywords/asymmetric-synthesis","display_name":"asymmetric synthesis","score":0.3019999861717224}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9507339000701904},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.8458470106124878},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.8226370811462402},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.8079889416694641},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.6983740329742432},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.5105489492416382},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.4755292236804962},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.04565632343292236},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/ol900667g","doi":"https://doi.org/10.1021/ol900667g","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ol900667g","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},{"id":"pmid:19422198","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19422198","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1605400511","https://openalex.org/W1970276483","https://openalex.org/W1990920093","https://openalex.org/W1995166961","https://openalex.org/W2002722462","https://openalex.org/W2004637628","https://openalex.org/W2020848534","https://openalex.org/W2028587577","https://openalex.org/W2076895571","https://openalex.org/W2087827420","https://openalex.org/W2087837854","https://openalex.org/W2088787815","https://openalex.org/W2094649104","https://openalex.org/W2097043687","https://openalex.org/W2108165384","https://openalex.org/W2140138186","https://openalex.org/W2151759890","https://openalex.org/W2153344602","https://openalex.org/W2180624303","https://openalex.org/W2949090149","https://openalex.org/W2949489870","https://openalex.org/W2951822305","https://openalex.org/W2952320320"],"related_works":["https://openalex.org/W2500568145","https://openalex.org/W2153344602","https://openalex.org/W2320528210","https://openalex.org/W2020848534","https://openalex.org/W2950788300","https://openalex.org/W2045353829","https://openalex.org/W2952350144","https://openalex.org/W2144729557","https://openalex.org/W1965453006","https://openalex.org/W2125505658"],"abstract_inverted_index":{"A":[0],"novel":[1],"H(8)BINOL-based":[2],"chiral":[3],"ligand":[4],"(S)-3":[5],"is":[6],"found":[7],"to":[8,14],"catalyze":[9],"the":[10,18],"alkyl":[11],"propiolate":[12],"addition":[13],"aliphatic":[15],"aldehydes":[16],"in":[17],"presence":[19],"of":[20],"ZnEt(2)":[21],"and":[22],"Ti(O(i)Pr)(4)":[23],"at":[24],"room":[25],"temperature":[26],"with":[27],"excellent":[28],"enantioselectivity":[29],"(89-97%":[30],"ee).":[31]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}