{"id":"https://openalex.org/W1976783643","doi":"https://doi.org/10.1016/j.molcatb.2003.09.005","title":"Application of factorial design to the study of an alcoholysis transformation promoted by cutinase immobilized on NaY zeolite and Accurel PA6","display_name":"Application of factorial design to the study of an alcoholysis transformation promoted by cutinase immobilized on NaY zeolite and Accurel PA6","publication_year":2003,"publication_date":"2003-10-27","ids":{"openalex":"https://openalex.org/W1976783643","doi":"https://doi.org/10.1016/j.molcatb.2003.09.005","mag":"1976783643"},"language":"en","primary_location":{"id":"doi:10.1016/j.molcatb.2003.09.005","doi":"https://doi.org/10.1016/j.molcatb.2003.09.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcatb.2003.09.005","pdf_url":null,"source":{"id":"https://openalex.org/S21009921","display_name":"Journal of Molecular Catalysis B Enzymatic","issn_l":"1381-1177","issn":["1381-1177","1873-3158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Catalysis B: Enzymatic","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1976783643"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015661187","display_name":"F\u00e1tima Nunes Serralha","orcid":"https://orcid.org/0000-0002-6731-3832","observed_orcids":["https://orcid.org/0000-0002-6731-3832"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"F.N. Serralha","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037608573","display_name":"Jos\u00e9 Manuel F.M. Lopes","orcid":"https://orcid.org/0000-0002-9830-7160","observed_orcids":["https://orcid.org/0000-0002-9830-7160"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"J.M. Lopes","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072730357","display_name":"Francisco Lemos","orcid":"https://orcid.org/0000-0002-7795-1002","observed_orcids":["https://orcid.org/0000-0002-7795-1002"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"F. Lemos","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"middle","author":{"id":null,"display_name":"F. Ram\u00f4a Ribeiro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"F. Ram\u00f4a Ribeiro","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034588525","display_name":"D.M.F. Prazeres","orcid":"https://orcid.org/0000-0002-6928-692X","observed_orcids":["https://orcid.org/0000-0002-6928-692X"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"D.M.F. Prazeres","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081316321","display_name":"Maria Raquel Aires-Barros","orcid":"https://orcid.org/0000-0002-1813-4280","observed_orcids":["https://orcid.org/0000-0002-1813-4280"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"M.R. Aires-Barros","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007145023","display_name":"Joaquim M. S. Cabral","orcid":"https://orcid.org/0000-0002-2405-5845","observed_orcids":["https://orcid.org/0000-0002-2405-5845"]},"institutions":[{"id":"https://openalex.org/I4387152517","display_name":"Instituto Superior T\u00e9cnico","ror":"https://ror.org/03db2by73","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4387152517"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"J.M.S. Cabral","raw_affiliation_strings":["Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u0131\u0301mica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]},{"raw_affiliation_string":"Centro de Engenharia Biol\u00f3gica e Qu\u00edmica, Instituto Superior T\u00e9cnico, Av. Rovisco Pais, 1049\u2013001 Lisbon, Portugal","institution_ids":["https://openalex.org/I4387152517"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037608573"],"corresponding_institution_ids":["https://openalex.org/I4387152517"],"apc_list":null,"apc_paid":null,"fwci":0.2792,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.44101348,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"27","issue":"1","first_page":"19","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11831","display_name":"Chemical Synthesis and Reactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cutinase","display_name":"cutinase","score":0.8370000123977661},{"id":"https://openalex.org/keywords/enzyme-immobilization","display_name":"enzyme immobilization","score":0.9710000157356262},{"id":"https://openalex.org/keywords/alcoholysis","display_name":"alcoholysis","score":0.796999990940094},{"id":"https://openalex.org/keywords/butyl-acetate","display_name":"butyl acetate","score":0.8769999742507935},{"id":"https://openalex.org/keywords/hexanol","display_name":"hexanol","score":0.984000027179718},{"id":"https://openalex.org/keywords/nay-zeolite","display_name":"NaY zeolite","score":0.847000002861023},{"id":"https://openalex.org/keywords/fusarium-solani-pisi","display_name":"Fusarium solani pisi","score":0.9390000104904175},{"id":"https://openalex.org/keywords/factorial-design","display_name":"factorial design","score":0.8420000076293945},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.5130000114440918},{"id":"https://openalex.org/keywords/reaction-conditions","display_name":"reaction conditions","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C2777613533","wikidata":"https://www.wikidata.org/wiki/Q4273972","display_name":"Cutinase","level":3,"score":0.9181719422340393},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7669090032577515},{"id":"https://openalex.org/C2781039482","wikidata":"https://www.wikidata.org/wiki/Q1616687","display_name":"Hexanol","level":3,"score":0.7245361804962158},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6299188733100891},{"id":"https://openalex.org/C106827334","wikidata":"https://www.wikidata.org/wiki/Q672821","display_name":"Molar concentration","level":2,"score":0.5610551238059998},{"id":"https://openalex.org/C169222746","wikidata":"https://www.wikidata.org/wiki/Q4116558","display_name":"Factorial experiment","level":2,"score":0.5576300621032715},{"id":"https://openalex.org/C2779013266","wikidata":"https://www.wikidata.org/wiki/Q411073","display_name":"Butyl acetate","level":3,"score":0.5194670557975769},{"id":"https://openalex.org/C16469947","wikidata":"https://www.wikidata.org/wiki/Q2400745","display_name":"Fractional factorial design","level":3,"score":0.5077530145645142},{"id":"https://openalex.org/C2778077586","wikidata":"https://www.wikidata.org/wiki/Q181332","display_name":"Zeolite","level":3,"score":0.505469799041748},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2872001528739929},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2604072690010071},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.10768121480941772},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molcatb.2003.09.005","doi":"https://doi.org/10.1016/j.molcatb.2003.09.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcatb.2003.09.005","pdf_url":null,"source":{"id":"https://openalex.org/S21009921","display_name":"Journal of Molecular Catalysis B Enzymatic","issn_l":"1381-1177","issn":["1381-1177","1873-3158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Catalysis B: Enzymatic","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W67724469","https://openalex.org/W153014257","https://openalex.org/W1775749144","https://openalex.org/W1969243570","https://openalex.org/W1988581920","https://openalex.org/W1990178106","https://openalex.org/W1994227860","https://openalex.org/W1999245400","https://openalex.org/W2003145882","https://openalex.org/W2010187213","https://openalex.org/W2018215401","https://openalex.org/W2039876018","https://openalex.org/W2048335668","https://openalex.org/W2056473105","https://openalex.org/W2081397997","https://openalex.org/W2090017129","https://openalex.org/W2100056564","https://openalex.org/W2117669255","https://openalex.org/W2147596210","https://openalex.org/W2154242672","https://openalex.org/W2317652448","https://openalex.org/W2334115141","https://openalex.org/W2334217271"],"related_works":["https://openalex.org/W2056473105","https://openalex.org/W2090017129","https://openalex.org/W7029266241","https://openalex.org/W7036234405","https://openalex.org/W33004530","https://openalex.org/W2039876018","https://openalex.org/W2217451464","https://openalex.org/W67724469","https://openalex.org/W2081397997","https://openalex.org/W2120167616"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}