{"id":"https://openalex.org/W1976708276","doi":"https://doi.org/10.1016/0022-2828(82)90130-4","title":"Activation of the glucocorticoid receptor*1","display_name":"Activation of the glucocorticoid receptor*1","publication_year":1982,"publication_date":"1982-09-01","ids":{"openalex":"https://openalex.org/W1976708276","doi":"https://doi.org/10.1016/0022-2828(82)90130-4","mag":"1976708276","pmid":"https://pubmed.ncbi.nlm.nih.gov/6754956"},"language":"en","primary_location":{"id":"doi:10.1016/0022-2828(82)90130-4","doi":"https://doi.org/10.1016/0022-2828(82)90130-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-2828(82)90130-4","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062814155","display_name":"Gerald Litwack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"G LITWACK","raw_affiliation_strings":["Fels Research Institute, Temple University School of Medicine, 3420 N. Broad Street, Philadelphia, Pennsylvania 19140, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute, Temple University School of Medicine, 3420 N. Broad Street, Philadelphia, Pennsylvania 19140, USA","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062814155"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":{"value":4120,"currency":"USD","value_usd":4120},"apc_paid":null,"fwci":0.2933,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.56011817,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"14","issue":null,"first_page":"59","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.9700000286102295},{"id":"https://openalex.org/keywords/receptor-activation","display_name":"receptor activation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/steroid-receptor-complex","display_name":"steroid-receptor complex","score":0.8550000190734863},{"id":"https://openalex.org/keywords/dna-binding-sites","display_name":"DNA binding sites","score":0.8130000233650208},{"id":"https://openalex.org/keywords/dephosphorylation","display_name":"dephosphorylation","score":0.8420000076293945},{"id":"https://openalex.org/keywords/calf-intestinal-alkaline-phosphatase","display_name":"calf intestinal alkaline phosphatase","score":0.8420000076293945},{"id":"https://openalex.org/keywords/receptor-modulators","display_name":"receptor modulators","score":0.6420000195503235},{"id":"https://openalex.org/keywords/pyridoxal-5-phosphate","display_name":"pyridoxal phosphate","score":0.9919999837875366},{"id":"https://openalex.org/keywords/receptor-isoforms","display_name":"receptor isoforms","score":0.5180000066757202},{"id":"https://openalex.org/keywords/dna-polymerase-alpha","display_name":"DNA polymerase alpha","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.6529086828231812},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5782434940338135},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.537403404712677},{"id":"https://openalex.org/C51445715","wikidata":"https://www.wikidata.org/wiki/Q410477","display_name":"Hormone response element","level":5,"score":0.49998044967651367},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.45102187991142273},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.44765743613243103},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42556095123291016},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4153793156147003},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34959107637405396},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.07815882563591003},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002614","descriptor_name":"Chelating Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004257","descriptor_name":"DNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007672","descriptor_name":"Kidney Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011732","descriptor_name":"Pyridoxal Phosphate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011987","descriptor_name":"Receptors, Steroid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012294","descriptor_name":"Rifamycins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0022-2828(82)90130-4","doi":"https://doi.org/10.1016/0022-2828(82)90130-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-2828(82)90130-4","pdf_url":null,"source":{"id":"https://openalex.org/S111163638","display_name":"Journal of Molecular and Cellular Cardiology","issn_l":"0022-2828","issn":["0022-2828","1095-8584"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular and Cellular Cardiology","raw_type":"journal-article"},{"id":"pmid:6754956","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6754956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular and cellular cardiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1516679052","https://openalex.org/W1544388792","https://openalex.org/W1548712478","https://openalex.org/W1589783526","https://openalex.org/W1969540823","https://openalex.org/W1992258926","https://openalex.org/W1996453077","https://openalex.org/W2001744408","https://openalex.org/W2013090048","https://openalex.org/W2014139892","https://openalex.org/W2018389970","https://openalex.org/W2019744397","https://openalex.org/W2023693348","https://openalex.org/W2024098392","https://openalex.org/W2028053733","https://openalex.org/W2046201653","https://openalex.org/W2089250490","https://openalex.org/W2093755100","https://openalex.org/W2119826308","https://openalex.org/W2123164383","https://openalex.org/W2152536790"],"related_works":["https://openalex.org/W2081455213","https://openalex.org/W151786770","https://openalex.org/W2042226424","https://openalex.org/W2024098392","https://openalex.org/W2034932795","https://openalex.org/W1548712478","https://openalex.org/W1574229173","https://openalex.org/W2079858846","https://openalex.org/W1620799981","https://openalex.org/W1533986732"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}