{"id":"https://openalex.org/W197650622","doi":null,"title":"Pr\u00e9curseurs adipocytaires et adipocytes humains d\u2019origine m\u00e9dullaire et sous-cutan\u00e9e : r\u00f4le dans l\u2019h\u00e9matopo\u00ef\u00e8se","display_name":"Pr\u00e9curseurs adipocytaires et adipocytes humains d\u2019origine m\u00e9dullaire et sous-cutan\u00e9e : r\u00f4le dans l\u2019h\u00e9matopo\u00ef\u00e8se","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W197650622","mag":"197650622"},"language":"fr","primary_location":{"id":"pmh:hdl:10068/790596","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/790596","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030565933","display_name":"Jill Corre","orcid":"https://orcid.org/0000-0003-1580-6106","observed_orcids":["https://orcid.org/0000-0003-1580-6106"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jill Corre","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1580-6106","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5030565933"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.09080000221729279,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.03660000115633011,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow-adipocytes","display_name":"bone marrow adipocytes","score":0.8920000195503235},{"id":"https://openalex.org/keywords/subcutaneous-adipose-tissue","display_name":"subcutaneous adipose tissue","score":0.7799999713897705},{"id":"https://openalex.org/keywords/adipose-derived-stem-cells","display_name":"adipose-derived stem cells","score":0.8529999852180481},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.8510000109672546},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cd34-cells","display_name":"CD34+ cells","score":0.8619999885559082},{"id":"https://openalex.org/keywords/hematopoietic-support","display_name":"hematopoietic support","score":0.7200000286102295},{"id":"https://openalex.org/keywords/stromal-microenvironment","display_name":"stromal microenvironment","score":0.7900000214576721},{"id":"https://openalex.org/keywords/myeloid-differentiation","display_name":"myeloid differentiation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/co-culture","display_name":"co-culture","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.7017266750335693},{"id":"https://openalex.org/C2993713153","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Hematopoietic cell","level":4,"score":0.4815088212490082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45310139656066895},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.18253734707832336},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.12436744570732117},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0703977644443512}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:hdl:10068/790596","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/790596","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"mag:197650622","doi":null,"is_oa":false,"landing_page_url":"http://www.theses.fr/2006TOU30129","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2790738201","https://openalex.org/W1867089830","https://openalex.org/W1893137998","https://openalex.org/W2323454487","https://openalex.org/W173553019","https://openalex.org/W7020476448","https://openalex.org/W1583349652","https://openalex.org/W7052434116","https://openalex.org/W1973848292","https://openalex.org/W7017341163"],"abstract_inverted_index":{"La":[0],"regulation":[1,129],"de":[2,12,31,45,63,65,67,70,72,78,80,106,124,130,134,168,181,184,208,211,225,232,235,242,249,256],"l\u2019hematopoiese":[3],"est":[4],"sous":[5],"la":[6,23,28,32,108,128,247,265],"dependance":[7],"d\u2019un":[8],"microenvironnement":[9],"stromal.":[10],"Peu":[11],"travaux":[13,216],"ont":[14,221],"porte":[15],"sur":[16,85,276],"les":[17,47,94,100,119,164,259],"adipocytes":[18,48,95,120,198,253],"medullaires,":[19,96],"qui":[20],"representent":[21],"pourtant":[22,51],"population":[24],"cellulaire":[25],"non":[26,199],"hematopoietique":[27,251],"plus":[29,150],"abondante":[30],"moelle":[33],"osseuse":[34],"chez":[35],"l\u2019homme":[36],"adulte":[37],"normal.":[38],"Longtemps":[39],"consideres":[40],"comme":[41,97,152,158],"un":[42,53,76,86,153,159,179,190],"simple":[43,154],"element":[44],"remplissage,":[46],"medullaires":[49,121,200],"semblent":[50],"jouer":[52],"role":[54],"dans":[55,127,163,218],"l\u2019hematopoiese,":[56],"essentiellement":[57],"par":[58],"le":[59,138,219,239],"biais":[60],"d\u2019une":[61,175],"secretion":[62],"proteines":[64],"matrice,":[66],"cytokines":[68,204],"et":[69,112,205,255,272],"facteurs":[71,207],"croissance.":[73],"Gr\u00e2ce":[74],"a":[75,145,213,282],"systeme":[77,241],"co-culture":[79],"progeniteurs":[81],"hematopoietiques":[82],"CD34+":[83],"ensemencees":[84],"stroma":[87],"adherent":[88],"constitue":[89],"d\u2019adipocytes,":[90],"nous":[91,244],"montrons":[92],"que":[93,118,223],"leurs":[98,257],"precurseurs":[99],"cellules":[101,182,226],"souches":[102,183],"mesenchymateuses,":[103],"sont":[104,122],"capables":[105],"supporter":[107],"differenciation":[109],"complete":[110],"myeloide":[111],"lymphoide":[113],"B.":[114],"Ces":[115,197,261],"resultats":[116],"confirment":[117],"impliques":[123],"maniere":[125],"active":[126],"l\u2019hematopoiese.":[131,214],"Au":[132],"cours":[133],"ces":[135],"dernieres":[136],"annees,":[137],"statut":[139],"du":[140],"tissu":[141,160,171],"adipeux":[142,172,230,271,281],"blanc":[143],"sous-cutane":[144],"evolue":[146],":":[147],"il":[148],"n\u2019est":[149],"considere":[151],"reservoir":[155],"energetique,":[156],"mais":[157],"secretoire":[161],"implique":[162],"grandes":[165],"regulations":[166],"hormonales":[167],"l\u2019organisme.":[169],"Le":[170],"blanc,":[173],"doue":[174],"grande":[176],"plasticite,":[177],"possede":[178],"compartiment":[180],"type":[185],"mesenchymateux":[186],"appelees":[187],"ADSC,":[188],"suscitant":[189],"interet":[191],"considerable":[192],"pour":[193],"leur":[194],"potentiel":[195],"therapeutique.":[196],"secretent":[201],"egalement":[202],"des":[203,206,228,252,267,269,274,279],"croissance":[209],"susceptibles":[210],"participer":[212],"Des":[215],"realises":[217],"laboratoire":[220],"montre":[222],"l'injection":[224],"derivees":[227],"tissus":[229,270],"permettait":[231],"reconstituer":[233],"l'hematopoiese":[234],"souris":[236],"irradiees.":[237],"Avec":[238],"meme":[240],"co-culture,":[243],"demontrons":[245],"ici":[246],"capacite":[248],"soutien":[250],"sous-cutanes":[254],"precurseurs,":[258],"ADSC.":[260],"donnees":[262],"originales":[263],"completent":[264],"caracterisation":[266],"composants":[268],"soulevent":[273],"hypotheses":[275],"l'eventuelle":[277],"contribution":[278],"depots":[280],"l'homeostasie":[283],"hematopoietique.":[284]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}