{"id":"https://openalex.org/W1976368909","doi":"https://doi.org/10.1007/bf02399669","title":"Effect of a partial trisomy in the mouse upon cellular and nuclear RNA","display_name":"Effect of a partial trisomy in the mouse upon cellular and nuclear RNA","publication_year":1989,"publication_date":"1989-08-01","ids":{"openalex":"https://openalex.org/W1976368909","doi":"https://doi.org/10.1007/bf02399669","mag":"1976368909","pmid":"https://pubmed.ncbi.nlm.nih.gov/2482729"},"language":"en","primary_location":{"id":"doi:10.1007/bf02399669","doi":"https://doi.org/10.1007/bf02399669","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02399669","pdf_url":null,"source":{"id":"https://openalex.org/S8388595","display_name":"Biochemical Genetics","issn_l":"0006-2928","issn":["0006-2928","1573-4927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055172628","display_name":"Adrian V. Rake","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. V. Rake","raw_affiliation_strings":["Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","Biological Sciences, 235 Biology Hall, Wright State University, Dayton"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","institution_ids":["https://openalex.org/I19648265"]},{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, Dayton","institution_ids":["https://openalex.org/I19648265"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078436554","display_name":"Behnaz B. Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Patel","raw_affiliation_strings":["Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","Biological Sciences, 235 Biology Hall, Wright State University, Dayton"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","institution_ids":["https://openalex.org/I19648265"]},{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, Dayton","institution_ids":["https://openalex.org/I19648265"]}]},{"author_position":"last","author":{"id":null,"display_name":"M. De Leon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. De Leon","raw_affiliation_strings":["Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","Biological Sciences, 235 Biology Hall, Wright State University, Dayton"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, 45435, Dayton, Ohio","institution_ids":["https://openalex.org/I19648265"]},{"raw_affiliation_string":"Biological Sciences, 235 Biology Hall, Wright State University, Dayton","institution_ids":["https://openalex.org/I19648265"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I19648265"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":null,"fwci":0.1289,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.38459452,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"7-8","first_page":"403","last_page":"416"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.5830000042915344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.5830000042915344,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.15189999341964722,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.12250000238418579,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/partial-trisomy","display_name":"partial trisomy","score":0.9649999737739563},{"id":"https://openalex.org/keywords/rna-synthesis-rate","display_name":"RNA synthesis rate","score":0.7879999876022339},{"id":"https://openalex.org/keywords/nucleosome-repeat-length","display_name":"nucleosome repeat length","score":0.7900000214576721},{"id":"https://openalex.org/keywords/chromatin-structure","display_name":"chromatin structure","score":0.7860000133514404},{"id":"https://openalex.org/keywords/nuclear-organization","display_name":"nuclear organization","score":0.7409999966621399},{"id":"https://openalex.org/keywords/liver-cell-nuclei","display_name":"liver nuclei","score":0.6840000152587891},{"id":"https://openalex.org/keywords/brain-nuclei","display_name":"brain nuclei","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8559813499450684},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.7948596477508545},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.7109850645065308},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6560887098312378},{"id":"https://openalex.org/C2776229224","wikidata":"https://www.wikidata.org/wiki/Q844903","display_name":"Trisomy","level":2,"score":0.5505148768424988},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5249426364898682},{"id":"https://openalex.org/C2780114586","wikidata":"https://www.wikidata.org/wiki/Q40260","display_name":"Cell nucleus","level":3,"score":0.4747612476348877},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.46939224004745483},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4359557032585144},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09211772680282593}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014314","descriptor_name":"Trisomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014529","descriptor_name":"Uridine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/bf02399669","doi":"https://doi.org/10.1007/bf02399669","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02399669","pdf_url":null,"source":{"id":"https://openalex.org/S8388595","display_name":"Biochemical Genetics","issn_l":"0006-2928","issn":["0006-2928","1573-4927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Genetics","raw_type":"journal-article"},{"id":"doi:10.1007/pl00020584","doi":"https://doi.org/10.1007/pl00020584","is_oa":false,"landing_page_url":"https://doi.org/10.1007/pl00020584","pdf_url":null,"source":{"id":"https://openalex.org/S8388595","display_name":"Biochemical Genetics","issn_l":"0006-2928","issn":["0006-2928","1573-4927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Genetics","raw_type":"journal-article"},{"id":"pmid:2482729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2482729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical genetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.5400000214576721}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W75191725","https://openalex.org/W1579482787","https://openalex.org/W1947752733","https://openalex.org/W1967274931","https://openalex.org/W1973403811","https://openalex.org/W1981465257","https://openalex.org/W1996675680","https://openalex.org/W1996966337","https://openalex.org/W2001918323","https://openalex.org/W2002373635","https://openalex.org/W2019628100","https://openalex.org/W2025500729","https://openalex.org/W2028368615","https://openalex.org/W2030519581","https://openalex.org/W2044498971","https://openalex.org/W2059300254","https://openalex.org/W2064377347","https://openalex.org/W2069043724","https://openalex.org/W2096628378","https://openalex.org/W2114446624","https://openalex.org/W2145017162","https://openalex.org/W2301290620","https://openalex.org/W2787023214","https://openalex.org/W2945368067","https://openalex.org/W4230797022"],"related_works":["https://openalex.org/W2114446624","https://openalex.org/W2395849554","https://openalex.org/W2287239330","https://openalex.org/W7093698597","https://openalex.org/W2161665242","https://openalex.org/W2238283086","https://openalex.org/W2025086505","https://openalex.org/W112058634","https://openalex.org/W2019380186","https://openalex.org/W1572806382"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}