{"id":"https://openalex.org/W1976368751","doi":"https://doi.org/10.1016/j.jneumeth.2011.03.019","title":"Kinematic optimization of deep brain stimulation across multiple motor symptoms in Parkinson's disease","display_name":"Kinematic optimization of deep brain stimulation across multiple motor symptoms in Parkinson's disease","publication_year":2011,"publication_date":"2011-04-09","ids":{"openalex":"https://openalex.org/W1976368751","doi":"https://doi.org/10.1016/j.jneumeth.2011.03.019","mag":"1976368751","pmid":"https://pubmed.ncbi.nlm.nih.gov/21459111","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3122330"},"language":"en","primary_location":{"id":"doi:10.1016/j.jneumeth.2011.03.019","doi":"https://doi.org/10.1016/j.jneumeth.2011.03.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jneumeth.2011.03.019","pdf_url":null,"source":{"id":"https://openalex.org/S132751470","display_name":"Journal of Neuroscience Methods","issn_l":"0165-0270","issn":["0165-0270","1872-678X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroscience Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3122330","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012410678","display_name":"Thomas O. Mera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124825","display_name":"Cleveland Medical Devices","ror":"https://ror.org/030p45079","country_code":"US","type":"company","lineage":["https://openalex.org/I4210124825"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas Mera","raw_affiliation_strings":["Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA. tmera@clevemed.com","Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA. tmera@clevemed.com","institution_ids":["https://openalex.org/I4210124825"]},{"raw_affiliation_string":"Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA","institution_ids":["https://openalex.org/I4210124825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047447270","display_name":"Jerrold L. Vitek","orcid":"https://orcid.org/0000-0002-2308-6535","observed_orcids":["https://orcid.org/0000-0002-2308-6535"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerrold L. Vitek","raw_affiliation_strings":["Center for Neurological Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","Department of Neuroscience, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurological Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Department of Neuroscience, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016841050","display_name":"Jay L. Alberts","orcid":"https://orcid.org/0000-0002-9379-3630","observed_orcids":["https://orcid.org/0000-0002-9379-3630"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4210110978","display_name":"Louis Stokes Cleveland VA Medical Center","ror":"https://ror.org/01vrybr67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210110978","https://openalex.org/I4210127612"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay L. Alberts","raw_affiliation_strings":["Center for Neurological Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","Louis Stokes Department of Veteran Affairs, FES Center, 10701 East Blvd, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neurological Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Louis Stokes Department of Veteran Affairs, FES Center, 10701 East Blvd, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210110978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113721447","display_name":"Joseph P. Giuffrida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124825","display_name":"Cleveland Medical Devices","ror":"https://ror.org/030p45079","country_code":"US","type":"company","lineage":["https://openalex.org/I4210124825"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph P. Giuffrida","raw_affiliation_strings":["Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Movement Disorders, Cleveland Medical Devices, Inc., 4415 Euclid Ave Suite 400, Cleveland, OH 44103, USA","institution_ids":["https://openalex.org/I4210124825"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5012410678"],"corresponding_institution_ids":["https://openalex.org/I4210124825"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":2.6345,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.88710901,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"198","issue":"2","first_page":"280","last_page":"286"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11123","display_name":"Obsessive-Compulsive Spectrum Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11274","display_name":"Botulinum Toxin and Related Neurological Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"deep brain stimulation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dbs-programming","display_name":"DBS programming","score":0.9610000252723694},{"id":"https://openalex.org/keywords/stimulation-parameter-optimization","display_name":"stimulation parameter optimization","score":0.7580000162124634},{"id":"https://openalex.org/keywords/tremor","display_name":"tremor","score":0.8640000224113464},{"id":"https://openalex.org/keywords/bradykinesia","display_name":"bradykinesia","score":1.0},{"id":"https://openalex.org/keywords/motor-symptoms","display_name":"motor symptoms","score":0.6179999709129333},{"id":"https://openalex.org/keywords/motion-analysis","display_name":"motion analysis","score":0.6520000100135803},{"id":"https://openalex.org/keywords/kinematic-data","display_name":"kinematic data","score":0.6510000228881836},{"id":"https://openalex.org/keywords/drug-induced-dyskinesia","display_name":"drug-induced dyskinesia","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.8677435517311096},{"id":"https://openalex.org/C2780405171","wikidata":"https://www.wikidata.org/wiki/Q629444","display_name":"Dyskinesia","level":4,"score":0.7579401731491089},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.6902221441268921},{"id":"https://openalex.org/C11940443","wikidata":"https://www.wikidata.org/wiki/Q16965645","display_name":"Slowness","level":2,"score":0.6876381635665894},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.6223055720329285},{"id":"https://openalex.org/C3018987647","wikidata":"https://www.wikidata.org/wiki/Q3221083","display_name":"Motor symptoms","level":4,"score":0.534442126750946},{"id":"https://openalex.org/C2778261627","wikidata":"https://www.wikidata.org/wiki/Q2608695","display_name":"Movement disorders","level":3,"score":0.4982109069824219},{"id":"https://openalex.org/C39920418","wikidata":"https://www.wikidata.org/wiki/Q11476","display_name":"Kinematics","level":2,"score":0.49076542258262634},{"id":"https://openalex.org/C2780112193","wikidata":"https://www.wikidata.org/wiki/Q693519","display_name":"Essential tremor","level":2,"score":0.4452729821205139},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41521328687667847},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41112127900123596},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3937842845916748},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.38198769092559814},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C74650414","wikidata":"https://www.wikidata.org/wiki/Q11397","display_name":"Classical mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D018476","descriptor_name":"Hypokinesia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D018476","descriptor_name":"Hypokinesia","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jneumeth.2011.03.019","doi":"https://doi.org/10.1016/j.jneumeth.2011.03.019","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jneumeth.2011.03.019","pdf_url":null,"source":{"id":"https://openalex.org/S132751470","display_name":"Journal of Neuroscience Methods","issn_l":"0165-0270","issn":["0165-0270","1872-678X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroscience Methods","raw_type":"journal-article"},{"id":"pmid:21459111","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21459111","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroscience methods","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2380823","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3122330","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3122330","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3122330","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurosci Methods","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2380823","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3122330","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3202246433","display_name":"ParkinTune: Automated PD Motor Symptom Assessment for DBS Programming","funder_award_id":"R44AG033520","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320309680","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1834763371","https://openalex.org/W1881759783","https://openalex.org/W1897459461","https://openalex.org/W1926592224","https://openalex.org/W1969852226","https://openalex.org/W1972418461","https://openalex.org/W1980480824","https://openalex.org/W1998123715","https://openalex.org/W1999702935","https://openalex.org/W2002314838","https://openalex.org/W2023251988","https://openalex.org/W2029940240","https://openalex.org/W2058018672","https://openalex.org/W2060707485","https://openalex.org/W2094629216","https://openalex.org/W2103265007","https://openalex.org/W2128464706","https://openalex.org/W2145039080","https://openalex.org/W2145665803","https://openalex.org/W2148051178","https://openalex.org/W2148764702","https://openalex.org/W2149476088","https://openalex.org/W2156660775","https://openalex.org/W2191811942","https://openalex.org/W2439429155","https://openalex.org/W3025643029"],"related_works":["https://openalex.org/W2183132719","https://openalex.org/W7154937198","https://openalex.org/W2135333429","https://openalex.org/W1975092621","https://openalex.org/W7134183305","https://openalex.org/W2907518401","https://openalex.org/W2743577354","https://openalex.org/W7147225859","https://openalex.org/W4401546395","https://openalex.org/W2518719065"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}