{"id":"https://openalex.org/W1976123200","doi":"https://doi.org/10.3109/00365529309098253","title":"Gallstone Size and the Risk of Gallbladder Cancer","display_name":"Gallstone Size and the Risk of Gallbladder Cancer","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W1976123200","doi":"https://doi.org/10.3109/00365529309098253","mag":"1976123200","pmid":"https://pubmed.ncbi.nlm.nih.gov/8322023"},"language":"en","primary_location":{"id":"doi:10.3109/00365529309098253","doi":"https://doi.org/10.3109/00365529309098253","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365529309098253","pdf_url":null,"source":{"id":"https://openalex.org/S55592950","display_name":"Scandinavian Journal of Gastroenterology","issn_l":"0036-5521","issn":["0036-5521","1502-7708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://rivm.openrepository.com/rivm/handle/10029/257319","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029764717","display_name":"Clara J. Moerman","orcid":"https://orcid.org/0000-0002-8527-7193","observed_orcids":["https://orcid.org/0000-0002-8527-7193"]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"C. J. Moerman","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036402068","display_name":"Frank J. Lagerwaard","orcid":"https://orcid.org/0000-0002-8740-2517","observed_orcids":["https://orcid.org/0000-0002-8740-2517"]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"F. J. Lagerwaard","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113992114","display_name":"H. Bas Bueno-de-Mesquita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"H. B. Bueno De Mesquita","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110171355","display_name":"A. van Dalen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. van Dalen","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110615478","display_name":"Maarten Simon van Leeuwen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. S. Van Leeuwen","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035287767","display_name":"P. A. H. A. M. Schrover","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P. A. H. A. M. Schrover","raw_affiliation_strings":["Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands","institution_ids":["https://openalex.org/I4210104433"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210104433"],"apc_list":null,"apc_paid":null,"fwci":1.1409,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.75345137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"28","issue":"6","first_page":"482","last_page":"486"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.033799998462200165,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gallstone-size","display_name":"gallstone size","score":0.8309999704360962},{"id":"https://openalex.org/keywords/gallbladder-cancer","display_name":"gallbladder cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/gallstones","display_name":"gallstones","score":0.8610000014305115},{"id":"https://openalex.org/keywords/gallbladder-mucosa","display_name":"gallbladder mucosa","score":0.8159999847412109},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.8240000009536743},{"id":"https://openalex.org/keywords/ultrasonography","display_name":"ultrasonography","score":0.8529999852180481},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2777148285","wikidata":"https://www.wikidata.org/wiki/Q64386","display_name":"Gallbladder","level":2,"score":0.8178722858428955},{"id":"https://openalex.org/C2779388726","wikidata":"https://www.wikidata.org/wiki/Q272714","display_name":"Gallstones","level":2,"score":0.815142035484314},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7833553552627563},{"id":"https://openalex.org/C2776534502","wikidata":"https://www.wikidata.org/wiki/Q977787","display_name":"Gallbladder cancer","level":3,"score":0.767162561416626},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5843756198883057},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5157513618469238},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.471605122089386},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.3510811924934387}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002769","descriptor_name":"Cholelithiasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002769","descriptor_name":"Cholelithiasis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005704","descriptor_name":"Gallbladder","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005706","descriptor_name":"Gallbladder Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.3109/00365529309098253","doi":"https://doi.org/10.3109/00365529309098253","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365529309098253","pdf_url":null,"source":{"id":"https://openalex.org/S55592950","display_name":"Scandinavian Journal of Gastroenterology","issn_l":"0036-5521","issn":["0036-5521","1502-7708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:8322023","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8322023","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of gastroenterology","raw_type":"Journal Article"},{"id":"pmh:oai:rivm.openrepository.com:10029/257319","doi":null,"is_oa":false,"landing_page_url":"http://www.rivm.nl/bibliotheek/rapporten/528803002.html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401814","display_name":"Rivm Repository (Netherlands National Institute for Public Health and the Environment)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104433","host_organization_name":"National Institute for Public Health and the Environment","host_organization_lineage":["https://openalex.org/I4210104433"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Onderzoeksrapport"},{"id":"pmh:oai:rivm.openrepository.com:10029/634475","doi":null,"is_oa":false,"landing_page_url":"https://rivm.openrepository.com/handle/10029/634475","pdf_url":null,"source":{"id":"https://openalex.org/S4306401814","display_name":"Rivm Repository (Netherlands National Institute for Public Health and the Environment)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104433","host_organization_name":"National Institute for Public Health and the Environment","host_organization_lineage":["https://openalex.org/I4210104433"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:rivm:oai:rivm.openrepository.com:10029/257319","doi":null,"is_oa":true,"landing_page_url":"http://rivm.openrepository.com/rivm/handle/10029/257319","pdf_url":null,"source":{"id":"https://openalex.org/S4306401681","display_name":"Rivm (National Institute for Public Health and the Environment)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104433","host_organization_name":"National Institute for Public Health and the Environment","host_organization_lineage":["https://openalex.org/I4210104433"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"mag:2589618745","doi":null,"is_oa":false,"landing_page_url":"https://rivm.openrepository.com/handle/10029/257319","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:rivm:oai:rivm.openrepository.com:10029/257319","doi":null,"is_oa":true,"landing_page_url":"http://rivm.openrepository.com/rivm/handle/10029/257319","pdf_url":null,"source":{"id":"https://openalex.org/S4306401681","display_name":"Rivm (National Institute for Public Health and the Environment)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104433","host_organization_name":"National Institute for Public Health and the Environment","host_organization_lineage":["https://openalex.org/I4210104433"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W6652091","https://openalex.org/W1515085711","https://openalex.org/W1531775649","https://openalex.org/W1877541547","https://openalex.org/W1967544048","https://openalex.org/W1971781961","https://openalex.org/W1975544110","https://openalex.org/W1976661620","https://openalex.org/W1987445521","https://openalex.org/W2041251344","https://openalex.org/W2083585617","https://openalex.org/W2101225662","https://openalex.org/W2110785249","https://openalex.org/W2113999752","https://openalex.org/W2115661884","https://openalex.org/W2181155305","https://openalex.org/W2337728933","https://openalex.org/W2394501810","https://openalex.org/W2395595266","https://openalex.org/W2409811948"],"related_works":["https://openalex.org/W2589618745","https://openalex.org/W2110785249","https://openalex.org/W7165037123","https://openalex.org/W2372777360","https://openalex.org/W3093924078","https://openalex.org/W2085437284","https://openalex.org/W3117662136","https://openalex.org/W2375503213","https://openalex.org/W1974670202","https://openalex.org/W7096107496"],"abstract_inverted_index":{"The":[0,125],"relation":[1,116],"between":[2,119],"gallstone":[3,53],"size":[4,25,49,105,121],"and":[5,67,71,92,100,122],"gallbladder":[6,39,56,77,123],"cancer":[7,78,98],"was":[8,26,117],"investigated":[9],"in":[10,19,81],"a":[11,20],"matched":[12,94,102],"hospital-based":[13],"case-control":[14],"study":[15],"of":[16,32,36,50,61,65],"surgical":[17,74],"patients":[18,75,91,99],"predominantly":[21],"white":[22],"population.":[23],"Stone":[24],"considered":[27],"to":[28,111],"be":[29,107],"an":[30],"indicator":[31],"the":[33,48,51,55,62],"damaging":[34],"effects":[35],"gallstones":[37],"on":[38],"mucosa,":[40],"which":[41],"may":[42],"enhance":[43],"carcinogenesis.":[44],"A":[45],"radiologist":[46],"determined":[47],"largest":[52],"within":[54],"by":[57],"reviewing":[58],"hard":[59],"copies":[60,86],"ultrasonographic":[63],"examinations":[64],"cases":[66],"controls.":[68,95],"Between":[69],"1983":[70],"1989,":[72],"83":[73],"with":[76],"were":[79,87],"identified":[80],"18":[82],"participating":[83],"hospitals.":[84],"Hard":[85],"available":[88],"for":[89,127],"72":[90],"208":[93],"For":[96],"43":[97],"98":[101],"controls":[103],"stone":[104,120],"could":[106],"determined.":[108],"In":[109],"contrast":[110],"two":[112],"other":[113],"studies,":[114],"no":[115],"found":[118],"cancer.":[124],"reasons":[126],"this":[128],"discrepancy":[129],"are":[130],"discussed.":[131]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":6},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}