{"id":"https://openalex.org/W1975888341","doi":"https://doi.org/10.1093/cvr/19.12.754","title":"Effects of extracellular potassium on slow response excitability in rabbit atrial trabeculae","display_name":"Effects of extracellular potassium on slow response excitability in rabbit atrial trabeculae","publication_year":1985,"publication_date":"1985-12-01","ids":{"openalex":"https://openalex.org/W1975888341","doi":"https://doi.org/10.1093/cvr/19.12.754","mag":"1975888341","pmid":"https://pubmed.ncbi.nlm.nih.gov/4084933"},"language":"en","primary_location":{"id":"doi:10.1093/cvr/19.12.754","doi":"https://doi.org/10.1093/cvr/19.12.754","is_oa":false,"landing_page_url":"https://doi.org/10.1093/cvr/19.12.754","pdf_url":null,"source":{"id":"https://openalex.org/S91067379","display_name":"Cardiovascular Research","issn_l":"0008-6363","issn":["0008-6363","1755-3245"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088989450","display_name":"Samuel Cukierman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"S. CUKIERMAN","raw_affiliation_strings":["From the Institute de Biofisica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute de Biofisica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941, Brasil","institution_ids":["https://openalex.org/I122140584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088989450"],"corresponding_institution_ids":["https://openalex.org/I122140584"],"apc_list":{"value":4715,"currency":"EUR","value_usd":5329},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.09706848,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"12","first_page":"754","last_page":"761"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extracellular-potassium","display_name":"extracellular potassium","score":0.9860000014305115},{"id":"https://openalex.org/keywords/atrial-trabeculae","display_name":"atrial trabeculae","score":0.8410000205039978},{"id":"https://openalex.org/keywords/resting-membrane-potential","display_name":"resting membrane potential","score":0.7979999780654907},{"id":"https://openalex.org/keywords/stimulation-frequency","display_name":"stimulation frequency","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.828000009059906},{"id":"https://openalex.org/keywords/electrogenesis","display_name":"electrogenesis","score":0.38199999928474426},{"id":"https://openalex.org/keywords/barium","display_name":"barium","score":0.6179999709129333}],"concepts":[{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.7790322303771973},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.6913617849349976},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6247016787528992},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5548612475395203},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4964626431465149},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.4915498197078705},{"id":"https://openalex.org/C181911157","wikidata":"https://www.wikidata.org/wiki/Q389844","display_name":"Membrane potential","level":2,"score":0.483175665140152},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.4594709277153015},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.4384240508079529},{"id":"https://openalex.org/C176674119","wikidata":"https://www.wikidata.org/wiki/Q11582","display_name":"Liter","level":2,"score":0.4206888675689697},{"id":"https://openalex.org/C114021368","wikidata":"https://www.wikidata.org/wiki/Q189265","display_name":"Atrium (architecture)","level":3,"score":0.4204854965209961},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39678606390953064},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.32876428961753845},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17692211270332336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1603510081768036},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15327727794647217},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002463","descriptor_name":"Cell Membrane Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/cvr/19.12.754","doi":"https://doi.org/10.1093/cvr/19.12.754","is_oa":false,"landing_page_url":"https://doi.org/10.1093/cvr/19.12.754","pdf_url":null,"source":{"id":"https://openalex.org/S91067379","display_name":"Cardiovascular Research","issn_l":"0008-6363","issn":["0008-6363","1755-3245"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Research","raw_type":"journal-article"},{"id":"pmid:4084933","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4084933","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2037418873","https://openalex.org/W3145921204","https://openalex.org/W2412024772","https://openalex.org/W2071155301","https://openalex.org/W1988293876","https://openalex.org/W2428140734","https://openalex.org/W2128751597","https://openalex.org/W2054141629","https://openalex.org/W1985477395","https://openalex.org/W2163020119"],"abstract_inverted_index":{"Small":[0],"trabeculae":[1],"were":[2,45],"excised":[3],"from":[4,100],"the":[5,33,55,122,139,168],"rabbit":[6],"left":[7],"atrium":[8],"and":[9,58,78,126],"exposed":[10],"to":[11,25,94,102,162,166],"1":[12,93],"mmol":[13,27,104],".":[14,28,105],"litre-1":[15],"Ba2+-Tyrode":[16],"solution":[17],"containing":[18],"variable":[19],"amounts":[20],"of":[21,32,39,53,76,134,141,150,170],"potassium":[22,85,157],"(range:":[23],"10":[24,101],"25":[26,103],"litre-1).":[29],"One":[30],"end":[31],"trabecula":[34],"was":[35],"stimulated":[36],"by":[37,82,92,114,146,155],"means":[38],"a":[40],"suction":[41],"electrode.":[42],"Intracellular":[43],"microelectrodes":[44],"employed":[46],"for":[47],"measuring":[48],"membrane":[49],"potentials.":[50],"In":[51],"presence":[52],"Ba2+,":[54],"cell":[56],"depolarises":[57],"slow":[59,110,135,151],"responses":[60,65],"can":[61],"be":[62],"elicited.":[63],"Slow":[64,71],"thus":[66],"obtained":[67],"do":[68],"not":[69],"propagate.":[70],"response":[72,111,136,152],"overshoot,":[73],"maximum":[74],"rate":[75],"rise":[77],"duration":[79],"are":[80],"depressed":[81,145],"increasing":[83],"extracellular":[84,156],"concentrations":[86],"([K+]o).":[87],"The":[88,107,132,148],"resting":[89],"potential":[90],"decreases":[91],"3":[95],"mV":[96],"on":[97,138],"changing":[98],"[K+]o":[99,115,130],"litre-1.":[106],"depression":[108],"in":[109,121,164],"overshoot":[112],"caused":[113,154],"is":[116,143,158],"compatible":[117],"with":[118],"an":[119,159],"increase":[120],"relationship":[123],"between":[124],"K+":[125],"Ca2+":[127],"permeabilities":[128],"as":[129],"increases.":[131],"dependence":[133],"excitability":[137],"frequency":[140],"stimulation":[142],"also":[144],"[K+]o.":[147],"inhibition":[149],"electrogenesis":[153],"important":[160],"phenomenon":[161],"consider":[163],"trying":[165],"understand":[167],"origin":[169],"certain":[171],"cardiac":[172],"arrhythmias.":[173]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}