{"id":"https://openalex.org/W1975807583","doi":"https://doi.org/10.1016/s1474-4422(12)70103-5","title":"Teratogenic effects of antiepileptic drugs","display_name":"Teratogenic effects of antiepileptic drugs","publication_year":2012,"publication_date":"2012-07-16","ids":{"openalex":"https://openalex.org/W1975807583","doi":"https://doi.org/10.1016/s1474-4422(12)70103-5","mag":"1975807583","pmid":"https://pubmed.ncbi.nlm.nih.gov/22805351"},"language":"en","primary_location":{"id":"doi:10.1016/s1474-4422(12)70103-5","doi":"https://doi.org/10.1016/s1474-4422(12)70103-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1474-4422(12)70103-5","pdf_url":null,"source":{"id":"https://openalex.org/S70053155","display_name":"The Lancet Neurology","issn_l":"1474-4422","issn":["1474-4422","1474-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Neurology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019416797","display_name":"Torbj\u00f6rn Tomson","orcid":"https://orcid.org/0000-0003-0554-5352","observed_orcids":["https://orcid.org/0000-0003-0554-5352"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Torbj\u00f6rn Tomson","raw_affiliation_strings":["Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. torbjorn.tomson@karolinska.se","Department of Clinical Neuroscience; Karolinska Institutet; Stockholm; Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. torbjorn.tomson@karolinska.se","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Clinical Neuroscience; Karolinska Institutet; Stockholm; Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015152627","display_name":"Dina Battino","orcid":"https://orcid.org/0000-0001-5784-9986","observed_orcids":["https://orcid.org/0000-0001-5784-9986"]},"institutions":[{"id":"https://openalex.org/I4210164485","display_name":"Fondazione IRCCS Istituto Neurologico Carlo Besta","ror":"https://ror.org/05rbx8m02","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210164485"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Dina Battino","raw_affiliation_strings":["Epilepsy Centre, Department of Neurophysiology and Experimental Epileptology, Istituto di Ricovero a Cura a Carattere Scientifico (IRCCS), Neurological Institute \u201cCarlo Besta\u201d Foundation, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Centre, Department of Neurophysiology and Experimental Epileptology, Istituto di Ricovero a Cura a Carattere Scientifico (IRCCS), Neurological Institute \u201cCarlo Besta\u201d Foundation, Milan, Italy","institution_ids":["https://openalex.org/I4210164485"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019416797"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":7280,"currency":"USD","value_usd":7280},"apc_paid":null,"fwci":4.7198,"has_fulltext":false,"cited_by_count":280,"citation_normalized_percentile":{"value":0.98328691,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"11","issue":"9","first_page":"803","last_page":"813"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.9919999837875366},{"id":"https://openalex.org/keywords/teratogenicity","display_name":"teratogenicity","score":0.9700000286102295},{"id":"https://openalex.org/keywords/epilepsy-in-pregnancy","display_name":"epilepsy in pregnancy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.8450000286102295},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.9419999718666077},{"id":"https://openalex.org/keywords/fetal-death","display_name":"fetal death","score":0.9120000004768372},{"id":"https://openalex.org/keywords/postnatal-development","display_name":"postnatal development","score":0.8159999847412109},{"id":"https://openalex.org/keywords/behavioral-problems","display_name":"behavioral problems","score":0.7649999856948853},{"id":"https://openalex.org/keywords/women-of-reproductive-age","display_name":"women of reproductive age","score":0.949999988079071},{"id":"https://openalex.org/keywords/migraine","display_name":"migraine","score":0.4959999918937683},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.833951473236084},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.7312029004096985},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.704072117805481},{"id":"https://openalex.org/C2994127763","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Antiepileptic drug","level":3,"score":0.6843608617782593},{"id":"https://openalex.org/C65290608","wikidata":"https://www.wikidata.org/wiki/Q631521","display_name":"Teratology","level":4,"score":0.5381188988685608},{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.5370634198188782},{"id":"https://openalex.org/C3019607859","wikidata":"https://www.wikidata.org/wiki/Q727096","display_name":"Congenital malformations","level":3,"score":0.535101056098938},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5316904783248901},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.47800150513648987},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.41353797912597656},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3973346948623657},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3298083543777466},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3128378689289093},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.23930978775024414},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000014","descriptor_name":"Abnormalities, Drug-Induced","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s1474-4422(12)70103-5","doi":"https://doi.org/10.1016/s1474-4422(12)70103-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1474-4422(12)70103-5","pdf_url":null,"source":{"id":"https://openalex.org/S70053155","display_name":"The Lancet Neurology","issn_l":"1474-4422","issn":["1474-4422","1474-4465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Neurology","raw_type":"journal-article"},{"id":"pmid:22805351","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22805351","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet. Neurology","raw_type":"Journal Article"},{"id":"mag:2181719022","doi":null,"is_oa":false,"landing_page_url":"https://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(12)70103-5.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322570","display_name":"Stockholms L\u00e4ns Landsting","ror":"https://ror.org/02zrae794"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":104,"referenced_works":["https://openalex.org/W168234803","https://openalex.org/W204642784","https://openalex.org/W1516445378","https://openalex.org/W1558095504","https://openalex.org/W1561979687","https://openalex.org/W1565270024","https://openalex.org/W1763211801","https://openalex.org/W1861864368","https://openalex.org/W1965683813","https://openalex.org/W1966442862","https://openalex.org/W1969259810","https://openalex.org/W1970167469","https://openalex.org/W1971019903","https://openalex.org/W1972804683","https://openalex.org/W1974102105","https://openalex.org/W1975978205","https://openalex.org/W1976797456","https://openalex.org/W1978483090","https://openalex.org/W1979432994","https://openalex.org/W1979656334","https://openalex.org/W1981876964","https://openalex.org/W1982197461","https://openalex.org/W1985123583","https://openalex.org/W1985361282","https://openalex.org/W1986579462","https://openalex.org/W1987705632","https://openalex.org/W1990622933","https://openalex.org/W1991197094","https://openalex.org/W1994240701","https://openalex.org/W1996158922","https://openalex.org/W2002761057","https://openalex.org/W2004023355","https://openalex.org/W2004239214","https://openalex.org/W2007876270","https://openalex.org/W2010923406","https://openalex.org/W2011939930","https://openalex.org/W2014112054","https://openalex.org/W2018546188","https://openalex.org/W2020892277","https://openalex.org/W2024331715","https://openalex.org/W2024493563","https://openalex.org/W2024914055","https://openalex.org/W2027307928","https://openalex.org/W2030596105","https://openalex.org/W2031334993","https://openalex.org/W2033553661","https://openalex.org/W2036312441","https://openalex.org/W2038349042","https://openalex.org/W2045248638","https://openalex.org/W2048937347","https://openalex.org/W2049253299","https://openalex.org/W2051047506","https://openalex.org/W2057801246","https://openalex.org/W2057892905","https://openalex.org/W2059236007","https://openalex.org/W2062960723","https://openalex.org/W2063250117","https://openalex.org/W2068531434","https://openalex.org/W2069279852","https://openalex.org/W2074762124","https://openalex.org/W2076472832","https://openalex.org/W2079209874","https://openalex.org/W2096764832","https://openalex.org/W2100288005","https://openalex.org/W2100387857","https://openalex.org/W2107469596","https://openalex.org/W2117265043","https://openalex.org/W2119186079","https://openalex.org/W2123722643","https://openalex.org/W2127099399","https://openalex.org/W2130993944","https://openalex.org/W2131979832","https://openalex.org/W2134224784","https://openalex.org/W2142190051","https://openalex.org/W2143268844","https://openalex.org/W2144491417","https://openalex.org/W2145714555","https://openalex.org/W2146629358","https://openalex.org/W2147848178","https://openalex.org/W2148084778","https://openalex.org/W2148147266","https://openalex.org/W2152008771","https://openalex.org/W2154476836","https://openalex.org/W2161668547","https://openalex.org/W2161759048","https://openalex.org/W2162780398","https://openalex.org/W2162933447","https://openalex.org/W2163963432","https://openalex.org/W2166575638","https://openalex.org/W2167158873","https://openalex.org/W2171069034","https://openalex.org/W2319312991","https://openalex.org/W2332426614","https://openalex.org/W2340322764","https://openalex.org/W2412026406","https://openalex.org/W2412533618","https://openalex.org/W2419546676","https://openalex.org/W2597670899","https://openalex.org/W2921007674","https://openalex.org/W2948021578","https://openalex.org/W4205614308","https://openalex.org/W4230246096","https://openalex.org/W4242601240","https://openalex.org/W4244214422"],"related_works":["https://openalex.org/W1992201505","https://openalex.org/W2049468776","https://openalex.org/W2743516724","https://openalex.org/W2063866301","https://openalex.org/W2514771561","https://openalex.org/W1982062764","https://openalex.org/W2705692778","https://openalex.org/W2999528132","https://openalex.org/W2435012428","https://openalex.org/W2614081837"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":27},{"year":2016,"cited_by_count":20},{"year":2015,"cited_by_count":34},{"year":2014,"cited_by_count":33},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}