{"id":"https://openalex.org/W1975367288","doi":"https://doi.org/10.1016/j.cyto.2011.10.013","title":"Effects by anthrax toxins on hematopoiesis: A key role for cytokines as mediators","display_name":"Effects by anthrax toxins on hematopoiesis: A key role for cytokines as mediators","publication_year":2011,"publication_date":"2011-11-16","ids":{"openalex":"https://openalex.org/W1975367288","doi":"https://doi.org/10.1016/j.cyto.2011.10.013","mag":"1975367288","pmid":"https://pubmed.ncbi.nlm.nih.gov/22082805"},"language":"en","primary_location":{"id":"doi:10.1016/j.cyto.2011.10.013","doi":"https://doi.org/10.1016/j.cyto.2011.10.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cyto.2011.10.013","pdf_url":null,"source":{"id":"https://openalex.org/S70396342","display_name":"Cytokine","issn_l":"1043-4666","issn":["1043-4666","1096-0023"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085147005","display_name":"Pranela Rameshwar","orcid":"https://orcid.org/0000-0003-0434-9034","observed_orcids":["https://orcid.org/0000-0003-0434-9034"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pranela Rameshwar","raw_affiliation_strings":["Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA. rameshwa@umdnj.edu","Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA. rameshwa@umdnj.edu","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021645422","display_name":"Elaine W. Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elaine W. Wong","raw_affiliation_strings":["Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050607880","display_name":"Nancy D Connell","orcid":"https://orcid.org/0000-0003-0489-3777","observed_orcids":["https://orcid.org/0000-0003-0489-3777"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy D. Connell","raw_affiliation_strings":["Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, United States","institution_ids":["https://openalex.org/I4402554120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085147005"],"corresponding_institution_ids":["https://openalex.org/I4402554120"],"apc_list":{"value":3220,"currency":"USD","value_usd":3220},"apc_paid":null,"fwci":0.2594,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54469547,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"57","issue":"1","first_page":"143","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.08340000361204147,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anthrax-toxin","display_name":"anthrax toxin","score":0.9739999771118164},{"id":"https://openalex.org/keywords/holotoxin","display_name":"holotoxin","score":0.8209999799728394},{"id":"https://openalex.org/keywords/protective-antigen","display_name":"protective antigen","score":0.9110000133514404},{"id":"https://openalex.org/keywords/lethal-factor","display_name":"lethal factor","score":0.9409999847412109},{"id":"https://openalex.org/keywords/edema-factor","display_name":"edema factor","score":1.0},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.968999981880188},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.8560000061988831},{"id":"https://openalex.org/keywords/cfu-gm","display_name":"CFU-GM","score":0.8529999852180481},{"id":"https://openalex.org/keywords/cfu-e","display_name":"CFU-E","score":0.996999979019165},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.7229999899864197},{"id":"https://openalex.org/keywords/mip-1alpha","display_name":"MIP-1\u03b1","score":0.9449999928474426},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9120000004768372},{"id":"https://openalex.org/keywords/sdf-1alpha","display_name":"SDF-1\u03b1","score":0.9950000047683716},{"id":"https://openalex.org/keywords/myeloid-progenitor-cells","display_name":"myeloid progenitor cells","score":0.7870000004768372},{"id":"https://openalex.org/keywords/erythroid-progenitors","display_name":"erythroid progenitor cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-marrow-stroma","display_name":"bone marrow stroma","score":0.7390000224113464},{"id":"https://openalex.org/keywords/hematopoietic-suppression","display_name":"hematopoietic suppression","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C41810244","wikidata":"https://www.wikidata.org/wiki/Q1935986","display_name":"Anthrax toxin","level":5,"score":0.8337507247924805},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6121160984039307},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.5256763100624084},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5146547555923462},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4948202967643738},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4818466901779175},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.43921101093292236},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3382752239704132},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3290061354637146},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.1795838177204132},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.17882364988327026},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001427","descriptor_name":"Bacterial Toxins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015672","descriptor_name":"Erythroid Precursor Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015672","descriptor_name":"Erythroid Precursor Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015672","descriptor_name":"Erythroid Precursor Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017154","descriptor_name":"Stromal Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D020169","descriptor_name":"Caspases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055014","descriptor_name":"Granulocyte-Macrophage Progenitor Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D055014","descriptor_name":"Granulocyte-Macrophage Progenitor Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D055014","descriptor_name":"Granulocyte-Macrophage Progenitor Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.cyto.2011.10.013","doi":"https://doi.org/10.1016/j.cyto.2011.10.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cyto.2011.10.013","pdf_url":null,"source":{"id":"https://openalex.org/S70396342","display_name":"Cytokine","issn_l":"1043-4666","issn":["1043-4666","1096-0023"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"journal-article"},{"id":"pmid:22082805","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22082805","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytokine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.7699999809265137,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3661858793","display_name":null,"funder_award_id":"AI63578","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G761832637","display_name":"Vaccine hurdle to anthrax and the emerging immune system","funder_award_id":"R21AI063578","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W112544822","https://openalex.org/W1590797494","https://openalex.org/W1642069536","https://openalex.org/W1870054118","https://openalex.org/W1962214447","https://openalex.org/W1979032042","https://openalex.org/W1979125021","https://openalex.org/W1980123055","https://openalex.org/W1982931293","https://openalex.org/W2001095885","https://openalex.org/W2008681940","https://openalex.org/W2014071869","https://openalex.org/W2018506593","https://openalex.org/W2029491035","https://openalex.org/W2036795046","https://openalex.org/W2039007181","https://openalex.org/W2056178904","https://openalex.org/W2065179596","https://openalex.org/W2080661111","https://openalex.org/W2086588775","https://openalex.org/W2091806012","https://openalex.org/W2099015185","https://openalex.org/W2114741924","https://openalex.org/W2123691156","https://openalex.org/W2125784517","https://openalex.org/W2126619407","https://openalex.org/W2130197297","https://openalex.org/W2135313322","https://openalex.org/W2151741779","https://openalex.org/W2167872871","https://openalex.org/W2177231732","https://openalex.org/W2418673765","https://openalex.org/W4206182597","https://openalex.org/W4229857880","https://openalex.org/W4240168163","https://openalex.org/W6639375509"],"related_works":["https://openalex.org/W1979032042","https://openalex.org/W3209005007","https://openalex.org/W2028227146","https://openalex.org/W2082798612","https://openalex.org/W2025092242","https://openalex.org/W2167872871","https://openalex.org/W2158036372","https://openalex.org/W2158637618","https://openalex.org/W2097008796","https://openalex.org/W1591698212"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}