{"id":"https://openalex.org/W1974875451","doi":"https://doi.org/10.1016/s0272-6386(01)80008-1","title":"Coadministration of ketoconazole and cyclosporine for kidney transplant recipients: Long-term follow-up and study of metabolic consequences","display_name":"Coadministration of ketoconazole and cyclosporine for kidney transplant recipients: Long-term follow-up and study of metabolic consequences","publication_year":2001,"publication_date":"2001-03-01","ids":{"openalex":"https://openalex.org/W1974875451","doi":"https://doi.org/10.1016/s0272-6386(01)80008-1","mag":"1974875451","pmid":"https://pubmed.ncbi.nlm.nih.gov/11228175"},"language":"en","primary_location":{"id":"doi:10.1016/s0272-6386(01)80008-1","doi":"https://doi.org/10.1016/s0272-6386(01)80008-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0272-6386(01)80008-1","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079290802","display_name":"Mohamed Abdel kader Sobh","orcid":"https://orcid.org/0000-0002-6065-5725","observed_orcids":["https://orcid.org/0000-0002-6065-5725"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed A. Sobh","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101691570","display_name":"Ahmed Farouk Aziz Hamdy","orcid":"https://orcid.org/0000-0002-7289-4942","observed_orcids":["https://orcid.org/0000-0002-7289-4942"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmed F. Hamdy","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081090655","display_name":"Amgad E. El Agroudy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Amgad E. El Agroudy","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071316778","display_name":"Kefaya El-Sayed","orcid":"https://orcid.org/0000-0002-8602-8834","observed_orcids":["https://orcid.org/0000-0002-8602-8834"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Kefaya El Sayed","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102858124","display_name":"Tarek Abdelmoneim El-Diasty","orcid":"https://orcid.org/0000-0002-2783-0851","observed_orcids":["https://orcid.org/0000-0002-2783-0851","https://orcid.org/0000-0002-0619-1149"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Tarek El-Diasty","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055102518","display_name":"Mohamed Adel Bakr","orcid":"https://orcid.org/0000-0002-3650-4353","observed_orcids":["https://orcid.org/0000-0002-3650-4353"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed A. Bakr","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023952567","display_name":"Mohamed A. Ghoneim","orcid":"https://orcid.org/0000-0003-4329-0346","observed_orcids":["https://orcid.org/0000-0003-4329-0346"]},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed A. Ghoneim","raw_affiliation_strings":["Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Nephrology Center, University of Mansoura, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I159247623"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":2.541,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.89353814,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"37","issue":"3","first_page":"510","last_page":"517"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ketoconazole","display_name":"ketoconazole","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cyclosporine","display_name":"cyclosporine","score":0.9959999918937683},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/drug-co-administration","display_name":"drug co-administration","score":0.5239999890327454},{"id":"https://openalex.org/keywords/cyclosporine-dose-reduction","display_name":"cyclosporine dose reduction","score":0.9380000233650208},{"id":"https://openalex.org/keywords/acute-rejection","display_name":"acute rejection","score":0.7590000033378601},{"id":"https://openalex.org/keywords/chronic-graft-dysfunction","display_name":"chronic graft dysfunction","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cyclosporine-nephrotoxicity","display_name":"cyclosporine nephrotoxicity","score":0.9459999799728394},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":0.796999990940094},{"id":"https://openalex.org/keywords/bone-mineral-content","display_name":"bone mineral content","score":0.7730000019073486},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.871999979019165},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.6850000023841858},{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.625},{"id":"https://openalex.org/keywords/graft-function","display_name":"graft function","score":0.652999997138977},{"id":"https://openalex.org/keywords/cost-reduction","display_name":"cost reduction","score":0.44699999690055847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9509330987930298},{"id":"https://openalex.org/C2781064554","wikidata":"https://www.wikidata.org/wiki/Q407883","display_name":"Ketoconazole","level":3,"score":0.890556812286377},{"id":"https://openalex.org/C2994498544","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplant","level":4,"score":0.5605867505073547},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.48168501257896423},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.47556132078170776},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.45934444665908813},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4310934245586395},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3864303231239319},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3726663887500763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36984124779701233},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.13527053594589233},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.11965605616569519},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D007654","descriptor_name":"Ketoconazole","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D007654","descriptor_name":"Ketoconazole","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007654","descriptor_name":"Ketoconazole","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016572","descriptor_name":"Cyclosporine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D016572","descriptor_name":"Cyclosporine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D016572","descriptor_name":"Cyclosporine","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0272-6386(01)80008-1","doi":"https://doi.org/10.1016/s0272-6386(01)80008-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0272-6386(01)80008-1","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},{"id":"doi:10.1053/ajkd.2001.22075","doi":"https://doi.org/10.1053/ajkd.2001.22075","is_oa":false,"landing_page_url":"https://doi.org/10.1053/ajkd.2001.22075","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},{"id":"pmid:11228175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11228175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1502613544","https://openalex.org/W1594041406","https://openalex.org/W1977986691","https://openalex.org/W1987013299","https://openalex.org/W2002924549","https://openalex.org/W2014681359","https://openalex.org/W2027650214","https://openalex.org/W2035460391","https://openalex.org/W2036039626","https://openalex.org/W2037453145","https://openalex.org/W2040717411","https://openalex.org/W2045005480","https://openalex.org/W2048644151","https://openalex.org/W2075791349","https://openalex.org/W2078807381","https://openalex.org/W2091609012","https://openalex.org/W2132378921","https://openalex.org/W2271735251","https://openalex.org/W2329944014","https://openalex.org/W2415767157","https://openalex.org/W2461285432","https://openalex.org/W2684451676","https://openalex.org/W3144653383","https://openalex.org/W4211218761","https://openalex.org/W4250916340"],"related_works":["https://openalex.org/W2082611367","https://openalex.org/W2035460391","https://openalex.org/W7099835729","https://openalex.org/W2109118966","https://openalex.org/W1963917724","https://openalex.org/W2043068583","https://openalex.org/W1977986691","https://openalex.org/W2021875728","https://openalex.org/W1594041406","https://openalex.org/W1986738603"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}