{"id":"https://openalex.org/W1974872243","doi":"https://doi.org/10.1074/jbc.273.28.17824","title":"Complete Exon-Intron Organization of the Human Gene for the \u03b11 Chain of Type XV Collagen (COL15A1) and Comparison with the Homologous Col18a1 Gene","display_name":"Complete Exon-Intron Organization of the Human Gene for the \u03b11 Chain of Type XV Collagen (COL15A1) and Comparison with the Homologous Col18a1 Gene","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W1974872243","doi":"https://doi.org/10.1074/jbc.273.28.17824","mag":"1974872243","pmid":"https://pubmed.ncbi.nlm.nih.gov/9651385"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.273.28.17824","doi":"https://doi.org/10.1074/jbc.273.28.17824","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.28.17824","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.273.28.17824","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065770075","display_name":"P\u00e4ivi M. H\u00e4gg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"P\u00e4ivi M. H\u00e4gg","raw_affiliation_strings":["Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111728320","display_name":"Anu Muona","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Anu Muona","raw_affiliation_strings":["Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082615393","display_name":"Jocelyne Li\u00e9tard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jocelyne Li\u00e9tard","raw_affiliation_strings":["Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034164399","display_name":"Sirpa Kivirikko","orcid":"https://orcid.org/0000-0002-9926-8802","observed_orcids":["https://orcid.org/0000-0002-9926-8802"]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Sirpa Kivirikko","raw_affiliation_strings":["Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036252076","display_name":"Taina A. Pihlajaniemi","orcid":"https://orcid.org/0000-0002-1664-9045","observed_orcids":["https://orcid.org/0000-0002-1664-9045"]},"institutions":[{"id":"https://openalex.org/I98381234","display_name":"University of Oulu","ror":"https://ror.org/03yj89h83","country_code":"FI","type":"education","lineage":["https://openalex.org/I98381234"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Taina Pihlajaniemi","raw_affiliation_strings":["Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]},{"raw_affiliation_string":"From the Collagen Research Unit, Biocenter, and Department of Medical Biochemistry, University of Oulu, Kajaanintie 52 A, FIN-90220 Oulu, Finland","institution_ids":["https://openalex.org/I98381234"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5036252076"],"corresponding_institution_ids":["https://openalex.org/I98381234"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":0.7826,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.67674802,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"273","issue":"28","first_page":"17824","last_page":"17831"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.42289999127388,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.42289999127388,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.14890000224113464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.12999999523162842,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/col15a1","display_name":"COL15A1","score":0.9950000047683716},{"id":"https://openalex.org/keywords/col18a1","display_name":"COL18A1","score":0.8949999809265137},{"id":"https://openalex.org/keywords/alpha1-chain","display_name":"alpha1 chain","score":0.5839999914169312},{"id":"https://openalex.org/keywords/exon-intron-organization","display_name":"exon-intron organization","score":0.8700000047683716},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.8389999866485596},{"id":"https://openalex.org/keywords/promoter","display_name":"promoter","score":0.7960000038146973},{"id":"https://openalex.org/keywords/sp1-binding-site","display_name":"Sp1 binding site","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cysteine-rich-motif","display_name":"cysteine-rich motif","score":0.7480000257492065},{"id":"https://openalex.org/keywords/exon-exon-junctions","display_name":"exon-exon junctions","score":0.6060000061988831},{"id":"https://openalex.org/keywords/intron-length","display_name":"intron length","score":0.703000009059906},{"id":"https://openalex.org/keywords/gene-evolution","display_name":"gene evolution","score":0.4880000054836273},{"id":"https://openalex.org/keywords/mouse-homolog","display_name":"mouse homolog","score":0.5009999871253967},{"id":"https://openalex.org/keywords/human-genes","display_name":"human genes","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.7702745199203491},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.7392013072967529},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.633663535118103},{"id":"https://openalex.org/C64894306","wikidata":"https://www.wikidata.org/wiki/Q849622","display_name":"Homologous chromosome","level":3,"score":0.5029763579368591},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4137672185897827},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3766833543777466},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35560551285743713}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016329","descriptor_name":"Sp1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017384","descriptor_name":"Sequence Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.273.28.17824","doi":"https://doi.org/10.1074/jbc.273.28.17824","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.28.17824","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:9651385","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9651385","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1074/jbc.273.28.17824","doi":"https://doi.org/10.1074/jbc.273.28.17824","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.28.17824","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1309511","https://openalex.org/W177541346","https://openalex.org/W580812585","https://openalex.org/W1008280890","https://openalex.org/W1502758571","https://openalex.org/W1528700820","https://openalex.org/W1542375841","https://openalex.org/W1543347748","https://openalex.org/W1584345674","https://openalex.org/W1606693434","https://openalex.org/W1888819061","https://openalex.org/W1969956117","https://openalex.org/W1971553231","https://openalex.org/W1981978155","https://openalex.org/W1991598333","https://openalex.org/W1994286344","https://openalex.org/W2006434572","https://openalex.org/W2011466486","https://openalex.org/W2017869427","https://openalex.org/W2044460712","https://openalex.org/W2049281007","https://openalex.org/W2059339519","https://openalex.org/W2065014938","https://openalex.org/W2067283439","https://openalex.org/W2069820119","https://openalex.org/W2070932057","https://openalex.org/W2075617346","https://openalex.org/W2084157979","https://openalex.org/W2097707959","https://openalex.org/W2115149771","https://openalex.org/W2119518116","https://openalex.org/W2134812217","https://openalex.org/W2138270253","https://openalex.org/W2144634347","https://openalex.org/W2146760000","https://openalex.org/W2204061729","https://openalex.org/W2314225431"],"related_works":["https://openalex.org/W2014500514","https://openalex.org/W1584345674","https://openalex.org/W1543347748","https://openalex.org/W2006512735","https://openalex.org/W2067283439","https://openalex.org/W1528700820","https://openalex.org/W2039330132","https://openalex.org/W1485583646","https://openalex.org/W1521900848","https://openalex.org/W2049281007"],"abstract_inverted_index":{"The":[0,22,73,139,200],"human":[1],"gene":[2],"for":[3],"the":[4,27,34,57,70,84,104,107,123,126,136,143,151,159,168,173,177,186,189,196,203,215,228],"alpha1":[5],"chain":[6,60],"of":[7,29,36,42,94,103,106,116,125,148,172,180,188,195,202],"type":[8],"XV":[9],"collagen":[10,59],"(COL15A1)":[11],"is":[12,24,219,232],"about":[13,235],"145":[14],"kilobases":[15],"in":[16,48,113,135,158,208,238],"size":[17],"and":[18,33,122,150,185,227,247],"contains":[19,76],"42":[20],"exons.":[21],"promoter":[23],"characterized":[25],"by":[26,167],"lack":[28],"a":[30,98,154,252],"TATAA":[31],"motif":[32],"presence":[35],"several":[37],"Sp1":[38],"binding":[39],"sites,":[40],"some":[41],"which":[43,55,96,164,193,218,231],"appeared":[44],"to":[45,83,91],"be":[46,243],"functional":[47],"transfected":[49],"HeLa":[50],"cells.":[51],"Comparison":[52],"with":[53,62,211],"Col18a1,":[54,95],"encodes":[56,97],"alpha1(XVIII)":[58],"homologous":[61,140],"alpha1(XV),":[63],"indicates":[64],"marked":[65],"structural":[66],"homology":[67,156],"spread":[68],"throughout":[69],"two":[71,108,137,174,212],"genes.":[72,138,240],"mouse":[74],"Col18a1":[75,248],"one":[77],"exon":[78,92],"more":[79],"than":[80,223],"COL15A1,":[81],"due":[82],"fact":[85],"that":[86,245],"COL15A1":[87,246],"lacks":[88],"sequences":[89],"corresponding":[90],"3":[93],"cysteine-rich":[99],"sequence":[100],"motif.":[101],"Twenty-five":[102],"exons":[105,141,149,152,197],"genes":[109],"are":[110,130,165,198,205,249],"almost":[111,133],"identical":[112,131,134],"size,":[114],"six":[115],"them":[117],"contain":[118],"conserved":[119],"split":[120],"codons,":[121],"locations":[124],"respective":[127],"exon-intron":[128],"junctions":[129],"or":[132],"include":[142],"closely":[144],"adjacent":[145],"first":[146,216],"pair":[147],"encoding":[153],"thrombospondin-1":[155],"found":[157],"N-terminal":[160],"noncollagenous":[161,182],"domain":[162,183],"1,":[163],"followed":[166],"most":[169,194],"variable":[170],"part":[171],"genes,":[175,210],"covering":[176],"C-terminal":[178],"half":[179],"their":[181],"1":[184],"beginning":[187],"collagenous":[190],"portion,":[191],"after":[192],"homologous.":[199],"lengths":[201],"introns":[204],"not":[206],"similar":[207],"these":[209],"exceptions,":[213],"namely":[214],"intron,":[217,230],"very":[220,233],"short,":[221],"less":[222],"100":[224],"base":[225],"pairs,":[226],"second":[229],"large,":[234],"50":[236],"kilobases,":[237],"both":[239],"It":[241],"can":[242],"concluded":[244],"derived":[250],"from":[251],"common":[253],"ancestor.":[254]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}