{"id":"https://openalex.org/W1974831425","doi":"https://doi.org/10.1038/sj.jid.5700414","title":"Intense Pulsed Light Therapy for Superficial Pigmented Lesions Evaluated by Reflectance-Mode Confocal Microscopy and Optical Coherence Tomography","display_name":"Intense Pulsed Light Therapy for Superficial Pigmented Lesions Evaluated by Reflectance-Mode Confocal Microscopy and Optical Coherence Tomography","publication_year":2006,"publication_date":"2006-06-01","ids":{"openalex":"https://openalex.org/W1974831425","doi":"https://doi.org/10.1038/sj.jid.5700414","mag":"1974831425","pmid":"https://pubmed.ncbi.nlm.nih.gov/16741506"},"language":"en","primary_location":{"id":"doi:10.1038/sj.jid.5700414","doi":"https://doi.org/10.1038/sj.jid.5700414","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.jid.5700414","pdf_url":null,"source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1038/sj.jid.5700414","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112546046","display_name":"Toyonobu Yamashita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123820","display_name":"Shiseido Group (Japan)","ror":"https://ror.org/03da3g825","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210123820"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Toyonobu Yamashita","raw_affiliation_strings":["Shiseido Research Center, Shin-Yokohama, Yokohama, Japan. toyonobu.yamashita@to.shiseido.co.jp","Shiseido Research Center, Shin-Yokohama, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan. toyonobu.yamashita@to.shiseido.co.jp","institution_ids":["https://openalex.org/I4210123820"]},{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan","institution_ids":["https://openalex.org/I4210123820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006482434","display_name":"Kei Negishi","orcid":"https://orcid.org/0000-0002-6121-020X","observed_orcids":["https://orcid.org/0000-0002-6121-020X"]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei Negishi","raw_affiliation_strings":["Aoyama Institute of Women's and Natural Medicine, Tokyo Women's Medical University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aoyama Institute of Women's and Natural Medicine, Tokyo Women's Medical University, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084349656","display_name":"Takeshi Hariya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123820","display_name":"Shiseido Group (Japan)","ror":"https://ror.org/03da3g825","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210123820"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Hariya","raw_affiliation_strings":["Shiseido Research Center, Shin-Yokohama, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan","institution_ids":["https://openalex.org/I4210123820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000826431","display_name":"Naomi Kunizawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123820","display_name":"Shiseido Group (Japan)","ror":"https://ror.org/03da3g825","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210123820"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naomi Kunizawa","raw_affiliation_strings":["Shiseido Research Center, Shin-Yokohama, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan","institution_ids":["https://openalex.org/I4210123820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033992777","display_name":"Kaori Ikuta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123820","display_name":"Shiseido Group (Japan)","ror":"https://ror.org/03da3g825","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210123820"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaori Ikuta","raw_affiliation_strings":["Shiseido Research Center, Shin-Yokohama, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan","institution_ids":["https://openalex.org/I4210123820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026543777","display_name":"Motohiro Yanai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123820","display_name":"Shiseido Group (Japan)","ror":"https://ror.org/03da3g825","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210123820"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motohiro Yanai","raw_affiliation_strings":["Shiseido Research Center, Shin-Yokohama, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shiseido Research Center, Shin-Yokohama, Yokohama, Japan","institution_ids":["https://openalex.org/I4210123820"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049856851","display_name":"Shingo Wakamatsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136522","display_name":"Tokyo Women's Medical University","ror":"https://ror.org/03kjjhe36","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210136522"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shingo Wakamatsu","raw_affiliation_strings":["Aoyama Institute of Women's and Natural Medicine, Tokyo Women's Medical University, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aoyama Institute of Women's and Natural Medicine, Tokyo Women's Medical University, Tokyo, Japan","institution_ids":["https://openalex.org/I4210136522"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112546046"],"corresponding_institution_ids":["https://openalex.org/I4210123820"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":7.208,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.9745067,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"126","issue":"10","first_page":"2281","last_page":"2286"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.01810000091791153,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intense-pulsed-light-therapy","display_name":"intense pulsed light therapy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/solar-lentigines","display_name":"liver spots","score":0.8669999837875366},{"id":"https://openalex.org/keywords/pigmented-skin-lesions","display_name":"pigmented skin lesions","score":0.8920000195503235},{"id":"https://openalex.org/keywords/epidermal-basal-layer","display_name":"epidermal basal layer","score":0.8859999775886536},{"id":"https://openalex.org/keywords/melanocytes","display_name":"melanocytes","score":0.6759999990463257},{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"optical coherence tomography","score":0.921999990940094},{"id":"https://openalex.org/keywords/hydroquinone","display_name":"hydroquinone","score":0.718999981880188},{"id":"https://openalex.org/keywords/q-switched-laser","display_name":"Q-switched laser","score":0.9850000143051147}],"concepts":[{"id":"https://openalex.org/C94435474","wikidata":"https://www.wikidata.org/wiki/Q1065756","display_name":"Melanosome","level":3,"score":0.8709558248519897},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.642707347869873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5022580623626709},{"id":"https://openalex.org/C136009344","wikidata":"https://www.wikidata.org/wiki/Q336201","display_name":"Confocal","level":2,"score":0.46103644371032715},{"id":"https://openalex.org/C2776458125","wikidata":"https://www.wikidata.org/wiki/Q1827343","display_name":"Epidermis (zoology)","level":2,"score":0.45453909039497375},{"id":"https://openalex.org/C2776714205","wikidata":"https://www.wikidata.org/wiki/Q1193171","display_name":"Intense pulsed light","level":2,"score":0.4496843218803406},{"id":"https://openalex.org/C2779178360","wikidata":"https://www.wikidata.org/wiki/Q902045","display_name":"Confocal microscopy","level":2,"score":0.448455274105072},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4380336105823517},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3928583264350891},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.38767245411872864},{"id":"https://openalex.org/C107538193","wikidata":"https://www.wikidata.org/wiki/Q187526","display_name":"Melanin","level":2,"score":0.3819791376590729},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.263405978679657},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.24373894929885864},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1742427945137024},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.15130287408828735},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1265239715576172},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.07028704881668091},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007911","descriptor_name":"Lentigo","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010789","descriptor_name":"Phototherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D017495","descriptor_name":"Hyperpigmentation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D017495","descriptor_name":"Hyperpigmentation","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020460","descriptor_name":"Melanosomes","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046529","descriptor_name":"Microscopy, Electron, Transmission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/sj.jid.5700414","doi":"https://doi.org/10.1038/sj.jid.5700414","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.jid.5700414","pdf_url":null,"source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},{"id":"pmid:16741506","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16741506","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of investigative dermatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/sj.jid.5700414","doi":"https://doi.org/10.1038/sj.jid.5700414","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.jid.5700414","pdf_url":null,"source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1975064825","https://openalex.org/W1977134049","https://openalex.org/W1982444630","https://openalex.org/W1986770703","https://openalex.org/W1991092865","https://openalex.org/W1996513213","https://openalex.org/W2021497248","https://openalex.org/W2028957994","https://openalex.org/W2030293894","https://openalex.org/W2038166075","https://openalex.org/W2043193298","https://openalex.org/W2061694580","https://openalex.org/W2064530127","https://openalex.org/W2070645949","https://openalex.org/W2085279180","https://openalex.org/W2106579290","https://openalex.org/W2111620906","https://openalex.org/W2112634516","https://openalex.org/W2123786318","https://openalex.org/W2138800197","https://openalex.org/W2148361228","https://openalex.org/W2158831156","https://openalex.org/W2165249254","https://openalex.org/W6680713561"],"related_works":["https://openalex.org/W4243993462","https://openalex.org/W2395266517","https://openalex.org/W2058871121","https://openalex.org/W4253098859","https://openalex.org/W3162482900","https://openalex.org/W2123786318","https://openalex.org/W2775727787","https://openalex.org/W2052129229","https://openalex.org/W2730134892","https://openalex.org/W1992496164"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}