{"id":"https://openalex.org/W1974767167","doi":"https://doi.org/10.1016/j.plantsci.2011.12.005","title":"Overproduction of recombinant proteins in plants","display_name":"Overproduction of recombinant proteins in plants","publication_year":2011,"publication_date":"2011-12-16","ids":{"openalex":"https://openalex.org/W1974767167","doi":"https://doi.org/10.1016/j.plantsci.2011.12.005","mag":"1974767167","pmid":"https://pubmed.ncbi.nlm.nih.gov/22284713"},"language":"en","primary_location":{"id":"doi:10.1016/j.plantsci.2011.12.005","doi":"https://doi.org/10.1016/j.plantsci.2011.12.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.plantsci.2011.12.005","pdf_url":null,"source":{"id":"https://openalex.org/S167743172","display_name":"Plant Science","issn_l":"0168-9452","issn":["0168-9452","1873-2259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Science","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052109757","display_name":"Erin M. Egelkrout","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149919469","display_name":"California Polytechnic State University","ror":"https://ror.org/001gpfp45","country_code":"US","type":"education","lineage":["https://openalex.org/I149919469"]},{"id":"https://openalex.org/I4210143010","display_name":"Applied Biotechnology Institute","ror":"https://ror.org/03qv28y75","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143010"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin Egelkrout","raw_affiliation_strings":["Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, USA","institution_ids":["https://openalex.org/I149919469","https://openalex.org/I4210143010"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Vidya Rajan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149919469","display_name":"California Polytechnic State University","ror":"https://ror.org/001gpfp45","country_code":"US","type":"education","lineage":["https://openalex.org/I149919469"]},{"id":"https://openalex.org/I4210143010","display_name":"Applied Biotechnology Institute","ror":"https://ror.org/03qv28y75","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143010"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vidya Rajan","raw_affiliation_strings":["Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, United States","institution_ids":["https://openalex.org/I149919469","https://openalex.org/I4210143010"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003338788","display_name":"John A. Howard","orcid":"https://orcid.org/0000-0002-5974-5416","observed_orcids":["https://orcid.org/0000-0002-5974-5416"]},"institutions":[{"id":"https://openalex.org/I149919469","display_name":"California Polytechnic State University","ror":"https://ror.org/001gpfp45","country_code":"US","type":"education","lineage":["https://openalex.org/I149919469"]},{"id":"https://openalex.org/I4210143010","display_name":"Applied Biotechnology Institute","ror":"https://ror.org/03qv28y75","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143010"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John A. Howard","raw_affiliation_strings":["Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Biotechnology Institute, Cal Poly Technology Park, Building 83, San Luis Obispo, CA 93407, United States","institution_ids":["https://openalex.org/I149919469","https://openalex.org/I4210143010"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5003338788"],"corresponding_institution_ids":["https://openalex.org/I149919469","https://openalex.org/I4210143010"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":1.1755,"has_fulltext":false,"cited_by_count":132,"citation_normalized_percentile":{"value":0.74626866,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"184","issue":null,"first_page":"83","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.9300000071525574},{"id":"https://openalex.org/keywords/genetically-modified-plants","display_name":"transgenic plants","score":0.9200000166893005},{"id":"https://openalex.org/keywords/protein-accumulation","display_name":"protein accumulation","score":0.906000018119812},{"id":"https://openalex.org/keywords/plant-expression-systems","display_name":"plant expression systems","score":0.7319999933242798},{"id":"https://openalex.org/keywords/germplasm-selection","display_name":"germplasm selection","score":0.6990000009536743},{"id":"https://openalex.org/keywords/protein-localization","display_name":"protein localization","score":0.5799999833106995},{"id":"https://openalex.org/keywords/transformation-method","display_name":"transformation method","score":0.46700000762939453},{"id":"https://openalex.org/keywords/translation-optimization","display_name":"translation optimization","score":0.8339999914169312},{"id":"https://openalex.org/keywords/cost-effective-manufacturing","display_name":"cost-effective manufacturing","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8369594812393188},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.6821175217628479},{"id":"https://openalex.org/C124420848","wikidata":"https://www.wikidata.org/wiki/Q333076","display_name":"Overproduction","level":3,"score":0.6511728763580322},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.5218914151191711},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.4830949306488037},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.47670596837997437},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.47437363862991333},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4074050188064575},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3270740211009979},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2687039375305176},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2019944190979004}],"mesh":[{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010944","descriptor_name":"Plants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.plantsci.2011.12.005","doi":"https://doi.org/10.1016/j.plantsci.2011.12.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.plantsci.2011.12.005","pdf_url":null,"source":{"id":"https://openalex.org/S167743172","display_name":"Plant Science","issn_l":"0168-9452","issn":["0168-9452","1873-2259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Science","raw_type":"journal-article"},{"id":"pmid:22284713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22284713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant science : an international journal of experimental plant biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4359000027179718,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":223,"referenced_works":["https://openalex.org/W24174317","https://openalex.org/W35886515","https://openalex.org/W57167446","https://openalex.org/W81770158","https://openalex.org/W108542326","https://openalex.org/W147891367","https://openalex.org/W191676690","https://openalex.org/W227845122","https://openalex.org/W1211778324","https://openalex.org/W1488937500","https://openalex.org/W1490215484","https://openalex.org/W1516813746","https://openalex.org/W1520552221","https://openalex.org/W1550375105","https://openalex.org/W1555979680","https://openalex.org/W1571594032","https://openalex.org/W1585483179","https://openalex.org/W1587761090","https://openalex.org/W1590932635","https://openalex.org/W1606565747","https://openalex.org/W1644535274","https://openalex.org/W1678010498","https://openalex.org/W1682922962","https://openalex.org/W1760665500","https://openalex.org/W1768050488","https://openalex.org/W1813218734","https://openalex.org/W1858671828","https://openalex.org/W1866842417","https://openalex.org/W1929105441","https://openalex.org/W1930341263","https://openalex.org/W1933830148","https://openalex.org/W1951665502","https://openalex.org/W1964157636","https://openalex.org/W1966305256","https://openalex.org/W1966887838","https://openalex.org/W1969770714","https://openalex.org/W1970960314","https://openalex.org/W1973036268","https://openalex.org/W1974330115","https://openalex.org/W1975513263","https://openalex.org/W1975759007","https://openalex.org/W1977289893","https://openalex.org/W1977294998","https://openalex.org/W1977491203","https://openalex.org/W1978382324","https://openalex.org/W1979965542","https://openalex.org/W1981509058","https://openalex.org/W1981614977","https://openalex.org/W1982542312","https://openalex.org/W1984343513","https://openalex.org/W1989805200","https://openalex.org/W1990353896","https://openalex.org/W1990849226","https://openalex.org/W1991416684","https://openalex.org/W1994218567","https://openalex.org/W1994805528","https://openalex.org/W1995471938","https://openalex.org/W1995774065","https://openalex.org/W1997212522","https://openalex.org/W1999150850","https://openalex.org/W2003520310","https://openalex.org/W2004362709","https://openalex.org/W2004676853","https://openalex.org/W2005506831","https://openalex.org/W2005848936","https://openalex.org/W2006607348","https://openalex.org/W2006814458","https://openalex.org/W2007885388","https://openalex.org/W2008557798","https://openalex.org/W2009258758","https://openalex.org/W2012686113","https://openalex.org/W2016080981","https://openalex.org/W2017099106","https://openalex.org/W2018848205","https://openalex.org/W2019007981","https://openalex.org/W2019622811","https://openalex.org/W2023689726","https://openalex.org/W2026258495","https://openalex.org/W2026594405","https://openalex.org/W2027045247","https://openalex.org/W2027876836","https://openalex.org/W2027945375","https://openalex.org/W2027969712","https://openalex.org/W2029502441","https://openalex.org/W2036532753","https://openalex.org/W2037108634","https://openalex.org/W2037214772","https://openalex.org/W2037593399","https://openalex.org/W2037688791","https://openalex.org/W2037793580","https://openalex.org/W2038393405","https://openalex.org/W2038811561","https://openalex.org/W2039789830","https://openalex.org/W2039909144","https://openalex.org/W2043734532","https://openalex.org/W2045310728","https://openalex.org/W2045830695","https://openalex.org/W2048035644","https://openalex.org/W2049324939","https://openalex.org/W2051649700","https://openalex.org/W2052766440","https://openalex.org/W2052813349","https://openalex.org/W2053876967","https://openalex.org/W2056158436","https://openalex.org/W2058278889","https://openalex.org/W2058793111","https://openalex.org/W2058830308","https://openalex.org/W2059230904","https://openalex.org/W2060037459","https://openalex.org/W2060797201","https://openalex.org/W2062606951","https://openalex.org/W2063671508","https://openalex.org/W2064330305","https://openalex.org/W2064483138","https://openalex.org/W2067041321","https://openalex.org/W2069165607","https://openalex.org/W2069275136","https://openalex.org/W2070090382","https://openalex.org/W2070932974","https://openalex.org/W2072330144","https://openalex.org/W2072803260","https://openalex.org/W2073409608","https://openalex.org/W2074804625","https://openalex.org/W2076873728","https://openalex.org/W2077009726","https://openalex.org/W2077228334","https://openalex.org/W2077400503","https://openalex.org/W2079298102","https://openalex.org/W2079784371","https://openalex.org/W2081374983","https://openalex.org/W2083113626","https://openalex.org/W2083425042","https://openalex.org/W2084334886","https://openalex.org/W2089184691","https://openalex.org/W2091926257","https://openalex.org/W2092198719","https://openalex.org/W2093250523","https://openalex.org/W2095180061","https://openalex.org/W2096591534","https://openalex.org/W2097043803","https://openalex.org/W2099414888","https://openalex.org/W2099763917","https://openalex.org/W2100361743","https://openalex.org/W2100690167","https://openalex.org/W2102508144","https://openalex.org/W2103634877","https://openalex.org/W2103986567","https://openalex.org/W2104004928","https://openalex.org/W2105160466","https://openalex.org/W2106823467","https://openalex.org/W2106935208","https://openalex.org/W2108733083","https://openalex.org/W2109164508","https://openalex.org/W2109729481","https://openalex.org/W2109744583","https://openalex.org/W2111621171","https://openalex.org/W2111824328","https://openalex.org/W2112483255","https://openalex.org/W2112754294","https://openalex.org/W2113278572","https://openalex.org/W2114644187","https://openalex.org/W2114649333","https://openalex.org/W2114908611","https://openalex.org/W2116640622","https://openalex.org/W2116700453","https://openalex.org/W2118728483","https://openalex.org/W2119898083","https://openalex.org/W2120215158","https://openalex.org/W2120998754","https://openalex.org/W2123958351","https://openalex.org/W2125795528","https://openalex.org/W2126123282","https://openalex.org/W2126512396","https://openalex.org/W2128479421","https://openalex.org/W2128966805","https://openalex.org/W2129113294","https://openalex.org/W2129168757","https://openalex.org/W2129604975","https://openalex.org/W2130142855","https://openalex.org/W2132540199","https://openalex.org/W2135015580","https://openalex.org/W2136364313","https://openalex.org/W2137690232","https://openalex.org/W2139751264","https://openalex.org/W2139880870","https://openalex.org/W2141052107","https://openalex.org/W2141794831","https://openalex.org/W2142297287","https://openalex.org/W2146156422","https://openalex.org/W2146387619","https://openalex.org/W2147522529","https://openalex.org/W2148918318","https://openalex.org/W2150451934","https://openalex.org/W2150895319","https://openalex.org/W2152312841","https://openalex.org/W2154858732","https://openalex.org/W2155534763","https://openalex.org/W2155989425","https://openalex.org/W2156852055","https://openalex.org/W2157212209","https://openalex.org/W2157760365","https://openalex.org/W2159554401","https://openalex.org/W2160802460","https://openalex.org/W2161002275","https://openalex.org/W2161553904","https://openalex.org/W2161714250","https://openalex.org/W2163779721","https://openalex.org/W2164618276","https://openalex.org/W2165071298","https://openalex.org/W2166936260","https://openalex.org/W2167381455","https://openalex.org/W2169177790","https://openalex.org/W2169915963","https://openalex.org/W2171356375","https://openalex.org/W2171567367","https://openalex.org/W2172195350","https://openalex.org/W2240027552","https://openalex.org/W2354977637","https://openalex.org/W2403353253","https://openalex.org/W2416466597","https://openalex.org/W4230046749","https://openalex.org/W6647770077","https://openalex.org/W6680402065"],"related_works":["https://openalex.org/W2142297287","https://openalex.org/W4416979699","https://openalex.org/W2996768333","https://openalex.org/W2089653069","https://openalex.org/W2621277177","https://openalex.org/W4394937837","https://openalex.org/W4285038249","https://openalex.org/W2744772165","https://openalex.org/W4407873460","https://openalex.org/W2393490282"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}