{"id":"https://openalex.org/W1973938481","doi":"https://doi.org/10.1016/j.pnpbp.2005.01.007","title":"Role of brain-derived neurotrophic factor in eating disorders: Recent findings and its pathophysiological implications","display_name":"Role of brain-derived neurotrophic factor in eating disorders: Recent findings and its pathophysiological implications","publication_year":2005,"publication_date":"2005-03-11","ids":{"openalex":"https://openalex.org/W1973938481","doi":"https://doi.org/10.1016/j.pnpbp.2005.01.007","mag":"1973938481","pmid":"https://pubmed.ncbi.nlm.nih.gov/15866349"},"language":"en","primary_location":{"id":"doi:10.1016/j.pnpbp.2005.01.007","doi":"https://doi.org/10.1016/j.pnpbp.2005.01.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pnpbp.2005.01.007","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032453300","display_name":"Kenji Hashimoto","orcid":"https://orcid.org/0000-0002-8892-0439","observed_orcids":["https://orcid.org/0000-0002-8892-0439"]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kenji Hashimoto","raw_affiliation_strings":["Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan. hashimoto@faculty.chiba-u.jp","Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan. hashimoto@faculty.chiba-u.jp","institution_ids":["https://openalex.org/I159385669"]},{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroki Koizumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki Koizumi","raw_affiliation_strings":["Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077286663","display_name":"Michiko Nakazato","orcid":"https://orcid.org/0000-0002-4025-7594","observed_orcids":["https://orcid.org/0000-0002-4025-7594"]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michiko Nakazato","raw_affiliation_strings":["Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053435376","display_name":"Eiji Shimizu","orcid":"https://orcid.org/0000-0002-6741-9338","observed_orcids":["https://orcid.org/0000-0002-6741-9338","https://orcid.org/0000-0002-6867-0727"]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eiji Shimizu","raw_affiliation_strings":["Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033793584","display_name":"Masaomi Iyo","orcid":"https://orcid.org/0000-0002-5384-857X","observed_orcids":["https://orcid.org/0000-0002-5384-857X"]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaomi Iyo","raw_affiliation_strings":["Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba 260-8670, Japan","institution_ids":["https://openalex.org/I159385669"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5032453300"],"corresponding_institution_ids":["https://openalex.org/I159385669"],"apc_list":{"value":4380,"currency":"USD","value_usd":4380},"apc_paid":null,"fwci":0.7319,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.56048387,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"29","issue":"4","first_page":"499","last_page":"504"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13393","display_name":"Child Nutrition and Feeding Issues","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":1.0},{"id":"https://openalex.org/keywords/eating-disorders","display_name":"eating disorders","score":0.9580000042915344},{"id":"https://openalex.org/keywords/anorexia-nervosa","display_name":"anorexia nervosa","score":1.0},{"id":"https://openalex.org/keywords/bulimia-nervosa","display_name":"bulimia nervosa","score":1.0},{"id":"https://openalex.org/keywords/bdnf-gene-polymorphism","display_name":"BDNF gene polymorphism","score":0.843999981880188},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8009999990463257},{"id":"https://openalex.org/keywords/serum-bdnf-levels","display_name":"serum BDNF","score":0.9459999799728394},{"id":"https://openalex.org/keywords/bdnf-knockout-mice","display_name":"BDNF knockout mice","score":0.8939999938011169},{"id":"https://openalex.org/keywords/p75-neurotrophin-receptor","display_name":"p75 neurotrophin receptor","score":0.9240000247955322},{"id":"https://openalex.org/keywords/trkb-receptor","display_name":"TrkB receptor","score":0.9240000247955322},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.7950000166893005},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.6790000200271606},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C2776394216","wikidata":"https://www.wikidata.org/wiki/Q373822","display_name":"Eating disorders","level":2,"score":0.8422870635986328},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.7031212449073792},{"id":"https://openalex.org/C2777556793","wikidata":"https://www.wikidata.org/wiki/Q64513386","display_name":"Bulimia nervosa","level":3,"score":0.6563337445259094},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.647609293460846},{"id":"https://openalex.org/C97124661","wikidata":"https://www.wikidata.org/wiki/Q14897782","display_name":"Tropomyosin receptor kinase B","level":4,"score":0.644137442111969},{"id":"https://openalex.org/C92020748","wikidata":"https://www.wikidata.org/wiki/Q420457","display_name":"Neurotrophin","level":3,"score":0.6112249493598938},{"id":"https://openalex.org/C2777031586","wikidata":"https://www.wikidata.org/wiki/Q131749","display_name":"Anorexia nervosa","level":3,"score":0.6076108813285828},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5700482726097107},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4621264636516571},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.45600709319114685},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41830888390541077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41036903858184814},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36146295070648193},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32551220059394836},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.321120023727417},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.25665128231048584}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001068","descriptor_name":"Feeding and Eating Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001068","descriptor_name":"Feeding and Eating Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010551","descriptor_name":"Personality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.pnpbp.2005.01.007","doi":"https://doi.org/10.1016/j.pnpbp.2005.01.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pnpbp.2005.01.007","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},{"id":"pmid:15866349","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15866349","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in neuro-psychopharmacology & biological psychiatry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W117431324","https://openalex.org/W141636555","https://openalex.org/W1484497860","https://openalex.org/W1576918670","https://openalex.org/W1639247225","https://openalex.org/W1925793145","https://openalex.org/W1966419092","https://openalex.org/W1968213313","https://openalex.org/W1978807302","https://openalex.org/W1979722180","https://openalex.org/W1983914274","https://openalex.org/W1984123296","https://openalex.org/W1986956972","https://openalex.org/W1987615735","https://openalex.org/W1999456081","https://openalex.org/W2004107819","https://openalex.org/W2007156391","https://openalex.org/W2009208338","https://openalex.org/W2009838896","https://openalex.org/W2010269783","https://openalex.org/W2015262351","https://openalex.org/W2024413432","https://openalex.org/W2027262024","https://openalex.org/W2027535421","https://openalex.org/W2029184795","https://openalex.org/W2030204732","https://openalex.org/W2031987419","https://openalex.org/W2038122755","https://openalex.org/W2046124560","https://openalex.org/W2046901540","https://openalex.org/W2047159816","https://openalex.org/W2048557710","https://openalex.org/W2053472601","https://openalex.org/W2066953122","https://openalex.org/W2070948105","https://openalex.org/W2071804866","https://openalex.org/W2079884579","https://openalex.org/W2087090756","https://openalex.org/W2098231907","https://openalex.org/W2106085993","https://openalex.org/W2130417276","https://openalex.org/W2131122797","https://openalex.org/W2139565721","https://openalex.org/W2151055409","https://openalex.org/W2159011576","https://openalex.org/W2159692236","https://openalex.org/W2163391687","https://openalex.org/W2165033042","https://openalex.org/W2169270953","https://openalex.org/W2170675493","https://openalex.org/W2170911475","https://openalex.org/W2312532289","https://openalex.org/W2421814529","https://openalex.org/W2502993979","https://openalex.org/W2779897803","https://openalex.org/W3099182054","https://openalex.org/W4211016487"],"related_works":["https://openalex.org/W1999170764","https://openalex.org/W2009838896","https://openalex.org/W2042475669","https://openalex.org/W4323108445","https://openalex.org/W2137198040","https://openalex.org/W2066953122","https://openalex.org/W2126175461","https://openalex.org/W1983195788","https://openalex.org/W1964385956","https://openalex.org/W4285730496"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}