{"id":"https://openalex.org/W1973665038","doi":"https://doi.org/10.1172/jci109723","title":"Contraction of Cultured Rat Glomerular Cells of Apparent Mesangial Origin after Stimulation with Angiotensin II and Arginine Vasopressin","display_name":"Contraction of Cultured Rat Glomerular Cells of Apparent Mesangial Origin after Stimulation with Angiotensin II and Arginine Vasopressin","publication_year":1980,"publication_date":"1980-03-01","ids":{"openalex":"https://openalex.org/W1973665038","doi":"https://doi.org/10.1172/jci109723","mag":"1973665038","pmid":"https://pubmed.ncbi.nlm.nih.gov/6153393","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/371419"},"language":"en","primary_location":{"id":"doi:10.1172/jci109723","doi":"https://doi.org/10.1172/jci109723","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109723","pdf_url":"http://www.jci.org/articles/view/109723/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jci.org/articles/view/109723/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042453107","display_name":"Dennis A. Ausiello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis A. Ausiello","raw_affiliation_strings":["Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074579464","display_name":"Jeffrey I. Kreisberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey I. Kreisberg","raw_affiliation_strings":["Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Christian Roy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Roy","raw_affiliation_strings":["Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112790533","display_name":"Morris J. Karnovsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I187986737","display_name":"Coll\u00e8ge de France","ror":"https://ror.org/04ex24z53","country_code":"FR","type":"education","lineage":["https://openalex.org/I187986737"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Morris J. Karnovsky","raw_affiliation_strings":["Laboratoire de Physiologie Cellulaire , College de France , Paris , France","Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Physiologie Cellulaire , College de France , Paris , France","institution_ids":["https://openalex.org/I187986737"]},{"raw_affiliation_string":"Medical Services (Renal Unit), Massachusetts General Hospital, altd Departmiientts of Meclicine and Pathology Harvard Medical School, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":20.4536,"has_fulltext":true,"cited_by_count":401,"citation_normalized_percentile":{"value":0.99649096,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"65","issue":"3","first_page":"754","last_page":"760"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesangial-cells","display_name":"mesangial cells","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cell-contraction","display_name":"cell contraction","score":0.6959999799728394},{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":0.9210000038146973},{"id":"https://openalex.org/keywords/angiotensin-ii","display_name":"angiotensin II","score":1.0},{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":0.8199999928474426},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9369999766349792},{"id":"https://openalex.org/keywords/camp","display_name":"cyclic AMP","score":0.8389999866485596},{"id":"https://openalex.org/keywords/cgmp","display_name":"cyclic GMP","score":0.9589999914169312},{"id":"https://openalex.org/keywords/hormone-receptor-interaction","display_name":"hormone-receptor interaction","score":0.7149999737739563},{"id":"https://openalex.org/keywords/renin-producing-cells","display_name":"renin-producing cells","score":0.6880000233650208}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7539994716644287},{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.7526137232780457},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7316723465919495},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.614629864692688},{"id":"https://openalex.org/C2779131090","wikidata":"https://www.wikidata.org/wiki/Q3331086","display_name":"Mesangial cell","level":3,"score":0.5592997074127197},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.5329863429069519},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.49916768074035645},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.45026567578315735},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.42395660281181335},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.4237782061100006},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42319750785827637},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3933759331703186},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.26351314783096313},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20043522119522095},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.19313505291938782},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.18639424443244934},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.13690096139907837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11188137531280518}],"mesh":[{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006152","descriptor_name":"Cyclic GMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007678","descriptor_name":"Kidney Glomerulus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007678","descriptor_name":"Kidney Glomerulus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008236","descriptor_name":"Lypressin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011459","descriptor_name":"Prostaglandins E, Synthetic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015056","descriptor_name":"1-Methyl-3-isobutylxanthine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1172/jci109723","doi":"https://doi.org/10.1172/jci109723","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109723","pdf_url":"http://www.jci.org/articles/view/109723/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:371419","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/371419","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Invest","raw_type":"Text"},{"id":"pmid:6153393","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6153393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical investigation","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.937.8440","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.937.8440","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dm5migu4zj3pb.cloudfront.net/manuscripts/109000/109723/JCI80109723.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1172/jci109723","doi":"https://doi.org/10.1172/jci109723","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109723","pdf_url":"http://www.jci.org/articles/view/109723/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6000000238418579}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1973665038.pdf","grobid_xml":"https://content.openalex.org/works/W1973665038.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W60021536","https://openalex.org/W1490352408","https://openalex.org/W1518913349","https://openalex.org/W1592059338","https://openalex.org/W1598617305","https://openalex.org/W1599995112","https://openalex.org/W1603068052","https://openalex.org/W1736907577","https://openalex.org/W1761008414","https://openalex.org/W1775749144","https://openalex.org/W1821013869","https://openalex.org/W1965853065","https://openalex.org/W1979800254","https://openalex.org/W1985305324","https://openalex.org/W1988683351","https://openalex.org/W2001668786","https://openalex.org/W2085315340","https://openalex.org/W2089351912","https://openalex.org/W2144447462","https://openalex.org/W2147463574","https://openalex.org/W2398707352","https://openalex.org/W2416766621","https://openalex.org/W2419796768","https://openalex.org/W2422490184","https://openalex.org/W2432403270","https://openalex.org/W2433890533","https://openalex.org/W2438878616","https://openalex.org/W2947531032"],"related_works":["https://openalex.org/W7098545940","https://openalex.org/W2409780606","https://openalex.org/W2467406837","https://openalex.org/W2013016672","https://openalex.org/W1972557535","https://openalex.org/W1988694819","https://openalex.org/W2053052223","https://openalex.org/W2020425660","https://openalex.org/W2312961008","https://openalex.org/W2213350680"],"abstract_inverted_index":{"Studies":[0],"to":[1,196,241],"identify":[2],"the":[3,198,202,219,227,268,283,290],"physiological":[4],"role":[5],"of":[6,15,19,50,110,115,146,150,189,204,214,222,229,270,285,301],"glomerular":[7,17,96,302],"mesangial":[8,21],"cells":[9,18,26,52,98,101,112,224,281,288],"were":[10,27,129,194],"undertaken":[11],"using":[12],"homogeneous":[13],"cultures":[14],"rat":[16,95],"apparent":[20,169],"origin":[22],"(MS).":[23],"Cultured":[24],"MS":[25,51,111,176,223,246,280],"treated":[28],"with":[29,235],"arginine":[30],"vasopressin":[31],"(AVP),":[32],"angiotensin":[33],"II":[34],"(AGII),":[35],"prostaglandin":[36,236],"E(2),":[37],"and":[38,44,77,119,158,165,272,292],"parathyroid":[39],"hormone.":[40],"AVP":[41,215],"(0.1":[42],"nM)":[43,47,217],"AGII":[45],"(1":[46,238],"stimulated":[48],"contraction":[49,109,142,254,271,295],"in":[53,93,226,245,289,299],"vitro":[54],"that":[55,141,180,279,293],"was":[56,113,143,152,162,171,191,255],"complete":[57],"by":[58,74],"2":[59],"min":[60,67,83],"at":[61,68,87],"37":[62],"degrees":[63,70,89],"C":[64,71],"or":[65,99],"10":[66,172],"23":[69,88],"as":[72,131,133],"observed":[73],"phase":[75],"contrast":[76],"electron":[78],"microscopy.":[79],"Relaxation":[80],"recurred":[81],"15":[82],"after":[84,136],"hormonal":[85,137],"addition":[86],"C.":[90],"Similar":[91,233],"experiments":[92,234],"cloned":[94],"epithelial":[97],"\"renin\"-producing":[100],"did":[102],"not":[103],"demonstrate":[104,140],"a":[105,144,230,242],"contractile":[106],"response.":[107],"The":[108,167],"independent":[114],"cyclic":[116,120,127,208,273],"AMP":[117],"(cAMP)":[118],"3',5'-guanosine":[121],"monophosphate":[122],"(cGMP)":[123],"production,":[124],"even":[125],"when":[126],"nucleotides":[128],"measured":[130],"early":[132],"30":[134],"s":[135],"stimulation.":[138],"To":[139],"function":[145],"hormone-receptor":[147],"interaction,":[148],"binding":[149,155,188],"[(3)H](8-lysine)vasopressin":[151,190],"studied.":[153],"Specific":[154],"for":[156,200,267],"1.6":[157],"5":[159],"nM":[160],"hormone":[161,258],"both":[163],"time-":[164],"dose-dependent.":[166],"estimated":[168],"affinity":[170],"nM.":[173],"In":[174],"late":[175],"cell":[177,207,247],"passages":[178],"(>16th)":[179],"no":[181,186,251],"longer":[182],"demonstrated":[183],"hormone-stimulated":[184],"contraction,":[185],"specific":[187],"observed.":[192,256],"Incubations":[193],"modified":[195],"optimize":[197],"conditions":[199],"detecting":[201],"effect":[203,252],"hormones":[205],"on":[206,253],"nucleotide":[209,274],"content.":[210,261],"A":[211],"supramaximal":[212],"concentration":[213],"(200":[216],"increased":[218],"cAMP":[220,248],"content":[221],"twofold":[225],"presence":[228],"phosphodiesterase":[231],"inhibitor.":[232],"E(2)":[237],"mug/ml)":[239],"led":[240],"1.5-6-fold":[243],"increase":[244],"content,":[249],"but":[250],"Neither":[257],"altered":[259],"cGMP":[260],"These":[262],"data":[263],"are":[264,282],"further":[265],"support":[266],"independence":[269],"production.":[275],"Our":[276],"studies":[277],"suggest":[278],"equivalent":[284],"smooth":[286],"muscle":[287],"glomerulus":[291],"their":[294],"may":[296],"be":[297],"important":[298],"control":[300],"filtration.":[303]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}