{"id":"https://openalex.org/W1973644206","doi":"https://doi.org/10.1007/s00467-011-1879-9","title":"Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome","display_name":"Prophylactic eculizumab prior to kidney transplantation for atypical hemolytic uremic syndrome","publication_year":2011,"publication_date":"2011-05-09","ids":{"openalex":"https://openalex.org/W1973644206","doi":"https://doi.org/10.1007/s00467-011-1879-9","mag":"1973644206","pmid":"https://pubmed.ncbi.nlm.nih.gov/21556717"},"language":"en","primary_location":{"id":"doi:10.1007/s00467-011-1879-9","doi":"https://doi.org/10.1007/s00467-011-1879-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00467-011-1879-9","pdf_url":null,"source":{"id":"https://openalex.org/S25178087","display_name":"Pediatric Nephrology","issn_l":"0931-041X","issn":["0931-041X","1432-198X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037273436","display_name":"Marcus Weitz","orcid":"https://orcid.org/0000-0002-1696-5646","observed_orcids":["https://orcid.org/0000-0002-1696-5646"]},"institutions":[{"id":"https://openalex.org/I4210125796","display_name":"University Children's Hospital T\u00fcbingen","ror":"https://ror.org/03esvmb28","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118","https://openalex.org/I4210125796"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Marcus Weitz","raw_affiliation_strings":["University Children's Hospital Tuebingen, Tuebingen, Germany. marcus.weitz@med.uni-tuebingen.de","University Children's Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Children's Hospital Tuebingen, Tuebingen, Germany. marcus.weitz@med.uni-tuebingen.de","institution_ids":["https://openalex.org/I4210125796"]},{"raw_affiliation_string":"University Children's Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210125796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076191343","display_name":"Oliver Amon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125796","display_name":"University Children's Hospital T\u00fcbingen","ror":"https://ror.org/03esvmb28","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118","https://openalex.org/I4210125796"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oliver Amon","raw_affiliation_strings":["University Children\u2019s Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Children\u2019s Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210125796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069859261","display_name":"Dirk Bassler","orcid":"https://orcid.org/0000-0003-2358-4419","observed_orcids":["https://orcid.org/0000-0003-2358-4419"]},"institutions":[{"id":"https://openalex.org/I4210125796","display_name":"University Children's Hospital T\u00fcbingen","ror":"https://ror.org/03esvmb28","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118","https://openalex.org/I4210125796"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk Bassler","raw_affiliation_strings":["University Children\u2019s Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Children\u2019s Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210125796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022953340","display_name":"Alfred Koenigsrainer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094118","display_name":"Universit\u00e4tsklinikum T\u00fcbingen","ror":"https://ror.org/00pjgxh97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alfred Koenigsrainer","raw_affiliation_strings":["Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210094118"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034708142","display_name":"Silvio Nadalin","orcid":"https://orcid.org/0000-0001-8803-6670","observed_orcids":["https://orcid.org/0000-0001-8803-6670"]},"institutions":[{"id":"https://openalex.org/I4210094118","display_name":"Universit\u00e4tsklinikum T\u00fcbingen","ror":"https://ror.org/00pjgxh97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Silvio Nadalin","raw_affiliation_strings":["Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General, Visceral and Transplant Surgery, University Hospital Tuebingen, Tuebingen, Germany","institution_ids":["https://openalex.org/I4210094118"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037273436"],"corresponding_institution_ids":["https://openalex.org/I4210125796"],"apc_list":{"value":4337,"currency":"USD","value_usd":4337},"apc_paid":null,"fwci":7.8931,"has_fulltext":false,"cited_by_count":106,"citation_normalized_percentile":{"value":0.98213197,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"26","issue":"8","first_page":"1325","last_page":"1329"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atypical-hemolytic-uremic-syndrome","display_name":"atypical hemolytic uremic syndrome","score":0.9869999885559082},{"id":"https://openalex.org/keywords/eculizumab","display_name":"eculizumab","score":0.9959999918937683},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9739999771118164},{"id":"https://openalex.org/keywords/alternative-complement-pathway","display_name":"alternative complement pathway","score":0.7789999842643738},{"id":"https://openalex.org/keywords/membrane-attack-complex","display_name":"membrane attack complex","score":0.8320000171661377},{"id":"https://openalex.org/keywords/prophylaxis","display_name":"prophylaxis","score":0.6809999942779541},{"id":"https://openalex.org/keywords/pediatric-patients","display_name":"pediatric patients","score":0.5680000185966492},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C2777991916","wikidata":"https://www.wikidata.org/wiki/Q421617","display_name":"Eculizumab","level":4,"score":0.9433689117431641},{"id":"https://openalex.org/C2777637130","wikidata":"https://www.wikidata.org/wiki/Q17165460","display_name":"Atypical hemolytic uremic syndrome","level":4,"score":0.9313242435455322},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8204214572906494},{"id":"https://openalex.org/C2777878052","wikidata":"https://www.wikidata.org/wiki/Q3312044","display_name":"Thrombotic microangiopathy","level":3,"score":0.6439304351806641},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6357060074806213},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.621237576007843},{"id":"https://openalex.org/C2778842783","wikidata":"https://www.wikidata.org/wiki/Q603502","display_name":"Plasmapheresis","level":3,"score":0.6127933263778687},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.5817059874534607},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.5720164179801941},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5346927046775818},{"id":"https://openalex.org/C14356644","wikidata":"https://www.wikidata.org/wiki/Q14911975","display_name":"Factor H","level":4,"score":0.5239917635917664},{"id":"https://openalex.org/C189446657","wikidata":"https://www.wikidata.org/wiki/Q4736500","display_name":"Alternative complement pathway","level":4,"score":0.513519823551178},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48229315876960754},{"id":"https://openalex.org/C71318922","wikidata":"https://www.wikidata.org/wiki/Q426181","display_name":"Complement component 5","level":4,"score":0.46472981572151184},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45715731382369995},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.452437162399292},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.41945797204971313},{"id":"https://openalex.org/C184404459","wikidata":"https://www.wikidata.org/wiki/Q5009828","display_name":"CD59","level":4,"score":0.4170122742652893},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.22911673784255981},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.18313178420066833}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006463","descriptor_name":"Hemolytic-Uremic Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006463","descriptor_name":"Hemolytic-Uremic Syndrome","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006463","descriptor_name":"Hemolytic-Uremic Syndrome","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017242","descriptor_name":"Complement Factor H","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055502","descriptor_name":"Secondary Prevention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D065766","descriptor_name":"Atypical Hemolytic Uremic Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00467-011-1879-9","doi":"https://doi.org/10.1007/s00467-011-1879-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00467-011-1879-9","pdf_url":null,"source":{"id":"https://openalex.org/S25178087","display_name":"Pediatric Nephrology","issn_l":"0931-041X","issn":["0931-041X","1432-198X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Nephrology","raw_type":"journal-article"},{"id":"pmid:21556717","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21556717","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric nephrology (Berlin, Germany)","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320327604","display_name":"Akershus Universitetssykehus","ror":"https://ror.org/0331wat71"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1970280471","https://openalex.org/W1970432269","https://openalex.org/W2011115907","https://openalex.org/W2012630248","https://openalex.org/W2013537340","https://openalex.org/W2017183118","https://openalex.org/W2048117130","https://openalex.org/W2051293525","https://openalex.org/W2054824588","https://openalex.org/W2089013072","https://openalex.org/W2090724120","https://openalex.org/W2102537411","https://openalex.org/W2125992604","https://openalex.org/W2126092981","https://openalex.org/W2136780004","https://openalex.org/W2138062831","https://openalex.org/W2149330659","https://openalex.org/W2157130010"],"related_works":["https://openalex.org/W1986736016","https://openalex.org/W2001318494","https://openalex.org/W2008274577","https://openalex.org/W4309030460","https://openalex.org/W2774452804","https://openalex.org/W4200097213","https://openalex.org/W2154494423","https://openalex.org/W2047723597","https://openalex.org/W2773539971","https://openalex.org/W2401824088"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":19},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}