{"id":"https://openalex.org/W1973509992","doi":"https://doi.org/10.1016/j.rgmx.2013.06.008","title":"Microbiota intestinal en los trastornos digestivos. Probi\u00f3ticos, prebi\u00f3ticos y simbi\u00f3ticos","display_name":"Microbiota intestinal en los trastornos digestivos. Probi\u00f3ticos, prebi\u00f3ticos y simbi\u00f3ticos","publication_year":2013,"publication_date":"2013-08-01","ids":{"openalex":"https://openalex.org/W1973509992","doi":"https://doi.org/10.1016/j.rgmx.2013.06.008","mag":"1973509992","pmid":"https://pubmed.ncbi.nlm.nih.gov/24041049"},"language":"es","primary_location":{"id":"doi:10.1016/j.rgmx.2013.06.008","doi":"https://doi.org/10.1016/j.rgmx.2013.06.008","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.rgmx.2013.06.008","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0375090613000748/pdf","source":{"id":"https://openalex.org/S4210200243","display_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","issn_l":"0375-0906","issn":["0375-0906","2255-5528"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex","norway-1","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S0375090613000748/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114073719","display_name":"Miguel Angel Valdovinos-D\u00edaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210097900","display_name":"Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n","ror":"https://ror.org/00xgvev73","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210097900","https://openalex.org/I4210128723"]},{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"M.\u00c1. Valdovinos-D\u00edaz","raw_affiliation_strings":["Profesor titular. Curso de posgrado de Gastroenterolog\u00eda. UNAM. Jefe del Laboratorio de motilidad gastrointestinal. Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n. Electronic address: ma_valdovinos@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Profesor titular. Curso de posgrado de Gastroenterolog\u00eda. UNAM. Jefe del Laboratorio de motilidad gastrointestinal. Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n. Electronic address: ma_valdovinos@yahoo.com","institution_ids":["https://openalex.org/I4210097900","https://openalex.org/I8961855"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5114073719"],"corresponding_institution_ids":["https://openalex.org/I4210097900","https://openalex.org/I8961855"],"apc_list":{"value":1200,"currency":"USD","value_usd":1200},"apc_paid":{"value":1200,"currency":"USD","value_usd":1200},"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.06395872,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"78","issue":null,"first_page":"25","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.04839999973773956,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0340999998152256,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9300000071525574},{"id":"https://openalex.org/keywords/dysbiosis","display_name":"dysbiosis","score":0.7599999904632568},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.7900000214576721},{"id":"https://openalex.org/keywords/prebiotics","display_name":"prebiotics","score":1.0},{"id":"https://openalex.org/keywords/synbiotics","display_name":"synbiotics","score":0.9869999885559082},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.8930000066757202},{"id":"https://openalex.org/keywords/duodenal-microbiota","display_name":"duodenal microbiota","score":0.8059999942779541},{"id":"https://openalex.org/keywords/fecal-microbiota-transplantation","display_name":"fecal microbiota transplantation","score":0.8740000128746033},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.47099998593330383}],"concepts":[{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41468819975852966},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40282127261161804}],"mesh":[{"descriptor_ui":"D004066","descriptor_name":"Digestive System Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D004066","descriptor_name":"Digestive System Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D043183","descriptor_name":"Irritable Bowel Syndrome","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056692","descriptor_name":"Prebiotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.rgmx.2013.06.008","doi":"https://doi.org/10.1016/j.rgmx.2013.06.008","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.rgmx.2013.06.008","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0375090613000748/pdf","source":{"id":"https://openalex.org/S4210200243","display_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","issn_l":"0375-0906","issn":["0375-0906","2255-5528"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex","norway-1","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","raw_type":"journal-article"},{"id":"pmid:24041049","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24041049","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de gastroenterologia de Mexico","raw_type":"Conference Proceedings"},{"id":"pmh:oai:doaj.org/article:575a1a3a3aa84c3eb095211ca024981e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/575a1a3a3aa84c3eb095211ca024981e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico, Vol 78, Iss S1, Pp 25-27 (2013)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.rgmx.2013.06.008","doi":"https://doi.org/10.1016/j.rgmx.2013.06.008","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.rgmx.2013.06.008","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0375090613000748/pdf","source":{"id":"https://openalex.org/S4210200243","display_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","issn_l":"0375-0906","issn":["0375-0906","2255-5528"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex","norway-1","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Gastroenterolog\u00eda de M\u00e9xico","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1973509992.pdf","grobid_xml":"https://content.openalex.org/works/W1973509992.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1026380542","https://openalex.org/W1134601962","https://openalex.org/W1168598963","https://openalex.org/W2137956141","https://openalex.org/W2220583024","https://openalex.org/W2227766743","https://openalex.org/W2248440054","https://openalex.org/W2266969085"],"related_works":["https://openalex.org/W7014159540","https://openalex.org/W152037736","https://openalex.org/W1990596100","https://openalex.org/W6931342713","https://openalex.org/W4311550381","https://openalex.org/W7067585208","https://openalex.org/W3011467368","https://openalex.org/W2017740280","https://openalex.org/W2779255061","https://openalex.org/W3126586124"],"abstract_inverted_index":{"Los":[0],"avances":[1],"en":[2,21,54,63,70,77,142,153,162,176,211,224],"las":[3,116,265],"t\u00e9cnicas":[4,171,232],"de":[5,11,19,30,60,80,84,123,131,160,165,180,186,189,198,205,221,248,261,276],"biolog\u00eda":[6],"molecular":[7],"han":[8,89,173],"peren":[9],"condiciones":[10],"salud":[12],"y":[13,33,67,76,98,111,118,157,179,230],"enfermedad.Ahora":[14],"sabemos":[15],"que":[16,28,34,42,48,115,148,183,237,263,270],"el":[17,29,35,43,64,71,78,121,146,158,252],"n\u00famero":[18],"bacterias":[20],"un":[22],"individuo":[23],"es":[24,52,194,243,255],"10":[25],"veces":[26,39],"mayor":[27],"c\u00e9lulas":[31],"humanas":[32],"microbioma":[36,253,259],"tiene":[37,149],"150":[38],"m\u00e1s":[40,119,139,256],"genes":[41],"genoma":[44],"humano.Se":[45],"ha":[46],"reconocido":[47],"la":[49,55,58,68,81,85,150,184,187,197,206,238,247,271],"microbiota":[50,94,124,151,188],"intestinal":[51,152],"fundamental":[53],"protecci\u00f3n":[56],"contra":[57],"invasi\u00f3n":[59],"g\u00e9rmenes":[61],"pat\u00f3genos,":[62],"metabolismo":[65],"energ\u00e9tico":[66],"nutrici\u00f3n,":[69],"desarrollo":[72],"del":[73,107,209,215,241,274],"sistema":[74],"inmune":[75],"mantenimiento":[79],"integridad":[82],"anat\u00f3mica":[83],"mucosa":[86,181],"intestinal.Asimismo,":[87],"se":[88,135,202],"establecido":[90],"asociaciones":[91],"entre":[92],"una":[93],"alterada":[95],"o":[96,127],"disbiosis":[97],"padecimientos":[99],"como":[100],"obesidad,":[101],"s\u00edndrome":[102],"metab\u00f3lico,":[103],"diabetes,":[104],"irritable,":[105],"trastornos":[106,155],"neurodesarrollo,":[108],"enfermedades":[109],"autoinmunes":[110],"alergias.Tambi\u00e9n":[112],"hemos":[113],"aprendido":[114],"cos,":[117],"recientemente,":[120],"trasplante":[122],"fecal":[125],"restaurar":[126],"corregir":[128],"los":[129,137,154,190,199,234],"estados":[130],"disbiosis.En":[132],"este":[133],"art\u00edculo":[134],"analizan":[136],"estudios":[138,169],"recientes":[140],"presentados":[141],"congresos":[143],"internacionales,":[144],"sobre":[145],"papel":[147],"digestivos":[156],"uso":[159],"probi\u00f3ticos":[161],"gastroenterolog\u00eda.":[163],"S\u00edndrome":[164],"intestino":[166],"irritable":[167],"(SII)Diversos":[168],"con":[170,192,226,278],"moleculares":[172],"mostrado":[174],"tanto":[175],"muestras":[177,220,249,266],"fecales":[178,267],"col\u00f3nica":[182],"composici\u00f3n":[185,239],"pacientes":[191,225,277],"SII":[193],"diferente":[195,245],"a":[196,246,264],"sujetos":[200,228],"normales.Poco":[201],"conoce":[203],"acerca":[204],"ecolog\u00eda":[207,272],"microbiana":[208,240,273],"duodeno":[210,242,275],"estos":[212],"sujetos.El":[213],"grupo":[214],"Dr.":[216],"Pimentel":[217],"1":[218],"estudi\u00f3":[219],"aspirado":[222],"duodenal":[223,254,260],"SII-D,":[227],"sanos":[229],"ratones.Usando":[231],"moleculares,":[233],"autores":[235],"demostraron":[236,269],"completamente":[244],"fecales.De":[250],"hecho,":[251],"parecido":[257],"al":[258],"ratones":[262],"humanas.Tambi\u00e9n":[268],"SII-D":[279],"fue":[280]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}