{"id":"https://openalex.org/W1973347559","doi":"https://doi.org/10.1016/j.vetimm.2011.03.017","title":"PKC isoenzymes in equine platelets and stimulus induced activation","display_name":"PKC isoenzymes in equine platelets and stimulus induced activation","publication_year":2011,"publication_date":"2011-04-19","ids":{"openalex":"https://openalex.org/W1973347559","doi":"https://doi.org/10.1016/j.vetimm.2011.03.017","mag":"1973347559","pmid":"https://pubmed.ncbi.nlm.nih.gov/21513989"},"language":"en","primary_location":{"id":"doi:10.1016/j.vetimm.2011.03.017","doi":"https://doi.org/10.1016/j.vetimm.2011.03.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vetimm.2011.03.017","pdf_url":null,"source":{"id":"https://openalex.org/S194416120","display_name":"Veterinary Immunology and Immunopathology","issn_l":"0165-2427","issn":["0165-2427","1873-2534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary Immunology and Immunopathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://researchonline.rvc.ac.uk/id/eprint/4977/1/4977.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019921121","display_name":"\u00cd. Aktan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133836048","display_name":"Royal Veterinary College","ror":"https://ror.org/01wka8n18","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"\u00cd. Aktan","raw_affiliation_strings":["Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK. iaktan@rvc.ac.uk","Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK. iaktan@rvc.ac.uk","institution_ids":["https://openalex.org/I133836048"]},{"raw_affiliation_string":"Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK","institution_ids":["https://openalex.org/I133836048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073134219","display_name":"Bettina Dunkel","orcid":"https://orcid.org/0000-0003-2041-2144","observed_orcids":["https://orcid.org/0000-0003-2041-2144"]},"institutions":[{"id":"https://openalex.org/I133836048","display_name":"Royal Veterinary College","ror":"https://ror.org/01wka8n18","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"B. Dunkel","raw_affiliation_strings":["Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK","Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK","institution_ids":["https://openalex.org/I133836048"]},{"raw_affiliation_string":"Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK","institution_ids":["https://openalex.org/I133836048"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007575726","display_name":"Fiona M Cunningham","orcid":"https://orcid.org/0000-0002-7445-2419","observed_orcids":["https://orcid.org/0000-0002-7445-2419"]},"institutions":[{"id":"https://openalex.org/I133836048","display_name":"Royal Veterinary College","ror":"https://ror.org/01wka8n18","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I133836048"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F.M. Cunningham","raw_affiliation_strings":["Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Basic Sciences, Royal Veterinary College, Hawkshead Lane, Hertfordshire AL9 7TA, UK","institution_ids":["https://openalex.org/I133836048"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019921121"],"corresponding_institution_ids":["https://openalex.org/I133836048"],"apc_list":{"value":3250,"currency":"USD","value_usd":3250},"apc_paid":null,"fwci":0.1088,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.43529597,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"141","issue":"3-4","first_page":"276","last_page":"282"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7856000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7856000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.19599999487400055,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-kinase-c-isoenzymes","display_name":"protein kinase C isoenzymes","score":0.9620000123977661},{"id":"https://openalex.org/keywords/platelet-activation","display_name":"platelet activation","score":0.8690000176429749},{"id":"https://openalex.org/keywords/pkcdelta","display_name":"PKC\u03b4","score":0.8690000176429749},{"id":"https://openalex.org/keywords/platelet-activating-factor","display_name":"platelet-activating factor","score":0.9900000095367432},{"id":"https://openalex.org/keywords/phorbol-myristate-acetate","display_name":"phorbol myristate acetate","score":0.9380000233650208},{"id":"https://openalex.org/keywords/novel-pkc","display_name":"novel PKC","score":0.871999979019165}],"concepts":[{"id":"https://openalex.org/C195794163","wikidata":"https://www.wikidata.org/wiki/Q420877","display_name":"Protein kinase C","level":3,"score":0.9173898100852966},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.7726794481277466},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.6949331760406494},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.6162528991699219},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.5334926247596741},{"id":"https://openalex.org/C3018697912","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Platelet activation","level":3,"score":0.4877529740333557},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48261508345603943},{"id":"https://openalex.org/C2779020240","wikidata":"https://www.wikidata.org/wiki/Q420577","display_name":"Platelet-activating factor","level":2,"score":0.47995856404304504},{"id":"https://openalex.org/C2780043322","wikidata":"https://www.wikidata.org/wiki/Q2705359","display_name":"Phorbol","level":4,"score":0.47363439202308655},{"id":"https://openalex.org/C2778920010","wikidata":"https://www.wikidata.org/wiki/Q410968","display_name":"Digitonin","level":3,"score":0.4403942823410034},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.4236699342727661},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4133196771144867},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40941932797431946},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3205074071884155},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.31902772188186646},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.299380362033844},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.27442336082458496},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2251121997833252},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18841350078582764},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12041494250297546}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006736","descriptor_name":"Horses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D011493","descriptor_name":"Protein Kinase C","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015971","descriptor_name":"Gene Expression Regulation, Enzymologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.vetimm.2011.03.017","doi":"https://doi.org/10.1016/j.vetimm.2011.03.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vetimm.2011.03.017","pdf_url":null,"source":{"id":"https://openalex.org/S194416120","display_name":"Veterinary Immunology and Immunopathology","issn_l":"0165-2427","issn":["0165-2427","1873-2534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary Immunology and Immunopathology","raw_type":"journal-article"},{"id":"pmid:21513989","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21513989","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Veterinary immunology and immunopathology","raw_type":"Journal Article"},{"id":"pmh:oai:researchonline.rvc.ac.uk:4977","doi":null,"is_oa":true,"landing_page_url":"https://researchonline.rvc.ac.uk/id/eprint/4977/1/4977.pdf","pdf_url":"https://researchonline.rvc.ac.uk/id/eprint/4977/1/4977.pdf","source":{"id":"https://openalex.org/S4306402069","display_name":"RVC Research Online (Royal Veterinary College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I133836048","host_organization_name":"Royal Veterinary College","host_organization_lineage":["https://openalex.org/I133836048"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:alma.44SUR_INST:11138707960002346","doi":null,"is_oa":false,"landing_page_url":"https://openresearch.surrey.ac.uk/esploro/outputs/journalArticle/PKC-isoenzymes-in-equine-platelets-and/99512012602346","pdf_url":null,"source":{"id":"https://openalex.org/S4210197018","display_name":"Open Research (University of Surrey)","issn_l":"2688-268X","issn":["2688-268X","2688-3988"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:epubs.surrey.ac.uk:826877","doi":null,"is_oa":false,"landing_page_url":"http://epubs.surrey.ac.uk/826877/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400680","display_name":"Surrey Research Insight Open Access (The University of Surrey)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28290843","host_organization_name":"University of Surrey","host_organization_lineage":["https://openalex.org/I28290843"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:researchonline.rvc.ac.uk:4977","doi":null,"is_oa":true,"landing_page_url":"https://researchonline.rvc.ac.uk/id/eprint/4977/1/4977.pdf","pdf_url":"https://researchonline.rvc.ac.uk/id/eprint/4977/1/4977.pdf","source":{"id":"https://openalex.org/S4306402069","display_name":"RVC Research Online (Royal Veterinary College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I133836048","host_organization_name":"Royal Veterinary College","host_organization_lineage":["https://openalex.org/I133836048"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320638","display_name":"Horserace Betting Levy Board","ror":"https://ror.org/02z2a9w02"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1549702212","https://openalex.org/W1596532570","https://openalex.org/W1598566391","https://openalex.org/W1607258414","https://openalex.org/W1678773327","https://openalex.org/W1938922647","https://openalex.org/W1943033915","https://openalex.org/W1964754149","https://openalex.org/W1967176356","https://openalex.org/W1969684801","https://openalex.org/W1974468399","https://openalex.org/W1980169797","https://openalex.org/W1980606673","https://openalex.org/W1980652099","https://openalex.org/W1990026949","https://openalex.org/W1991264067","https://openalex.org/W1996587934","https://openalex.org/W2001031266","https://openalex.org/W2004243381","https://openalex.org/W2007424618","https://openalex.org/W2007711402","https://openalex.org/W2010297202","https://openalex.org/W2015571904","https://openalex.org/W2015572452","https://openalex.org/W2035472478","https://openalex.org/W2049468323","https://openalex.org/W2052049148","https://openalex.org/W2054266243","https://openalex.org/W2062053430","https://openalex.org/W2064252897","https://openalex.org/W2070860745","https://openalex.org/W2073405171","https://openalex.org/W2075951376","https://openalex.org/W2081637712","https://openalex.org/W2101346679","https://openalex.org/W2101723197","https://openalex.org/W2106877372","https://openalex.org/W2148943593","https://openalex.org/W2152955882","https://openalex.org/W2171703111","https://openalex.org/W2239689618","https://openalex.org/W2403734881"],"related_works":["https://openalex.org/W1991264067","https://openalex.org/W1967176356","https://openalex.org/W2104388133","https://openalex.org/W2073405171","https://openalex.org/W2171703111","https://openalex.org/W4322384827","https://openalex.org/W1977173640","https://openalex.org/W2101346679","https://openalex.org/W1549702212","https://openalex.org/W2332045404"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
