{"id":"https://openalex.org/W1972944746","doi":null,"title":"[Prediction of natively unfolded regions in protein chain].","display_name":"[Prediction of natively unfolded regions in protein chain].","publication_year":2006,"publication_date":"2006-03-01","ids":{"openalex":"https://openalex.org/W1972944746","mag":"1972944746","pmid":"https://pubmed.ncbi.nlm.nih.gov/16637275"},"language":"ru","primary_location":{"id":"pmid:16637275","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16637275","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekuliarnaia biologiia","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090341452","display_name":"O V Galzitskaia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137602","display_name":"Institute of Protein Research","ror":"https://ror.org/0489f0s93","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210137602"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"O V Galzitskaia","raw_affiliation_strings":["Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia","institution_ids":["https://openalex.org/I4210137602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111541028","display_name":"S A Garbuzinski\u012d","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137602","display_name":"Institute of Protein Research","ror":"https://ror.org/0489f0s93","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210137602"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"S A Garbuzinski\u012d","raw_affiliation_strings":["Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia","institution_ids":["https://openalex.org/I4210137602"]}]},{"author_position":"last","author":{"id":null,"display_name":"M Iu Lobanov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137602","display_name":"Institute of Protein Research","ror":"https://ror.org/0489f0s93","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210137602"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"M Iu Lobanov","raw_affiliation_strings":["Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Protein Research, Russian Academy of Sciences Pushchino Moscow Region Russia","institution_ids":["https://openalex.org/I4210137602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210137602"],"apc_list":null,"apc_paid":null,"fwci":1.4597,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.78062392,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"40","issue":"2","first_page":"341","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-folding-prediction","display_name":"protein folding prediction","score":0.7749999761581421},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"protein structure prediction","score":0.49399998784065247},{"id":"https://openalex.org/keywords/globular-proteins","display_name":"globular proteins","score":0.640999972820282},{"id":"https://openalex.org/keywords/hydrophobicity","display_name":"hydrophobicity","score":0.6259999871253967},{"id":"https://openalex.org/keywords/net-charge","display_name":"net charge","score":0.8370000123977661},{"id":"https://openalex.org/keywords/protein-chains","display_name":"protein chains","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C105168689","wikidata":"https://www.wikidata.org/wiki/Q901969","display_name":"Globular protein","level":2,"score":0.7019684910774231},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.5040713548660278},{"id":"https://openalex.org/C2994376932","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Amino acid residue","level":4,"score":0.49355900287628174},{"id":"https://openalex.org/C139447449","wikidata":"https://www.wikidata.org/wiki/Q14633900","display_name":"Unfolded protein response","level":3,"score":0.4592205882072449},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.41249340772628784},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4107389748096466},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3273085355758667},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2999890446662903},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.26883214712142944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2526807188987732},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17523348331451416},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:16637275","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16637275","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekuliarnaia biologiia","raw_type":"English Abstract"},{"id":"mag:1972944746","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16637275","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1593425281","https://openalex.org/W1720678970","https://openalex.org/W1968910000","https://openalex.org/W1972235557","https://openalex.org/W1975304761","https://openalex.org/W2006192061","https://openalex.org/W2014776147","https://openalex.org/W2016170088","https://openalex.org/W2051119339","https://openalex.org/W2070602158","https://openalex.org/W2073745520","https://openalex.org/W2085277871","https://openalex.org/W2092153867","https://openalex.org/W2101600610","https://openalex.org/W2104412724","https://openalex.org/W2107496962","https://openalex.org/W2114823344","https://openalex.org/W2126064524","https://openalex.org/W2134327751","https://openalex.org/W2149472608","https://openalex.org/W2152265734","https://openalex.org/W2161199282","https://openalex.org/W2168769487","https://openalex.org/W2918011059","https://openalex.org/W4239620712"],"related_works":["https://openalex.org/W4297822793","https://openalex.org/W2134327751","https://openalex.org/W2802688195","https://openalex.org/W6921622227","https://openalex.org/W2056514958","https://openalex.org/W2964239553","https://openalex.org/W1748564764","https://openalex.org/W2076682739","https://openalex.org/W2199143916","https://openalex.org/W7095705841"],"abstract_inverted_index":{"We":[0],"have":[1],"shown":[2],"that":[3,167],"the":[4,38,42,49,56,63,80,134,162,171],"ability":[5],"of":[6,45,55,59,69,82,91,104,109,128,133,137,142,151,153,156,174],"a":[7,29,35],"protein":[8,84,138,147],"to":[9,115,186],"be":[10,22,123],"in":[11,14,73,102,146],"globular":[12,74,93],"or":[13,131],"natively":[15,96,143,158,177],"unfolded":[16,97,144,159,178],"state":[17,75,136],"(under":[18],"native":[19,135],"conditions)":[20],"may":[21,122],"determined":[23],"(besides":[24],"low":[25],"overall":[26],"hydrophobicity":[27,117],"and":[28,94,139,183,191],"large":[30],"net":[31],"charge)":[32],"by":[33],"such":[34],"property":[36],"as":[37],"average":[39,43,57],"environment":[40],"density,":[41],"number":[44,58],"residues":[46,60,72,190],"enclosed":[47,61],"at":[48,62],"given":[50,64],"distance.":[51],"A":[52],"statistical":[53],"scale":[54,88,121],"distance":[65],"for":[66,89,126,140],"20":[67],"types":[68],"amino":[70],"acid":[71],"has":[76,170],"been":[77],"created":[78],"on":[79],"basis":[81],"6626":[83],"structures.":[85],"Using":[86],"this":[87],"separation":[90],"80":[92],"90":[95],"proteins":[98,105,193],"we":[99],"fail":[100],"only":[101],"11%":[103],"(compared":[106],"with":[107,161],"17%":[108],"errors":[110],"which":[111],"are":[112],"observed":[113],"if":[114,185],"use":[116],"scale).":[118],"The":[119,149],"present":[120],"used":[124],"both":[125],"prediction":[127,141],"form":[129],"(folded":[130],"unfolded)":[132],"regions":[145,160,179],"chains.":[148],"results":[150],"comparison":[152],"our":[154,168],"method":[155,169],"predicting":[157],"other":[163],"known":[164],"methods":[165],"show":[166],"highest":[172],"fraction":[173],"correctly":[175],"predicted":[176],"(that":[180],"is":[181],"87%":[182],"77%":[184],"make":[187],"averaging":[188],"over":[189,192],"correspondingly).":[194]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}