{"id":"https://openalex.org/W1972811451","doi":"https://doi.org/10.1073/pnas.67.1.193","title":"Antigenic Study of Unfertilized Mouse Eggs: Cross Reactivity with SV40-Induced Antigens","display_name":"Antigenic Study of Unfertilized Mouse Eggs: Cross Reactivity with SV40-Induced Antigens","publication_year":1970,"publication_date":"1970-09-01","ids":{"openalex":"https://openalex.org/W1972811451","doi":"https://doi.org/10.1073/pnas.67.1.193","mag":"1972811451","pmid":"https://pubmed.ncbi.nlm.nih.gov/4318777","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/283187"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.67.1.193","doi":"https://doi.org/10.1073/pnas.67.1.193","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.67.1.193","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/283187","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031090444","display_name":"Wanda Baranska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322052","display_name":"The Wistar Institute","ror":"https://ror.org/04wncat98","country_code":"US","type":"facility","lineage":["https://openalex.org/I102322052"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wanda Baranska","raw_affiliation_strings":["THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104","institution_ids":["https://openalex.org/I102322052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113445445","display_name":"P. Koldovsk\u00fd","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322052","display_name":"The Wistar Institute","ror":"https://ror.org/04wncat98","country_code":"US","type":"facility","lineage":["https://openalex.org/I102322052"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pavel Koldovsky","raw_affiliation_strings":["THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104","institution_ids":["https://openalex.org/I102322052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050328478","display_name":"Hilary Koprowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322052","display_name":"The Wistar Institute","ror":"https://ror.org/04wncat98","country_code":"US","type":"facility","lineage":["https://openalex.org/I102322052"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hilary Koprowski","raw_affiliation_strings":["THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PENNSYLVANIA 19104","institution_ids":["https://openalex.org/I102322052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I102322052"],"apc_list":null,"apc_paid":null,"fwci":28.3952,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.99817677,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"67","issue":"1","first_page":"193","last_page":"199"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.18569999933242798,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.18569999933242798,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.17790000140666962,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.16850000619888306,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cross-reactivity","display_name":"cross-reactivity","score":0.8709999918937683},{"id":"https://openalex.org/keywords/complement-dependent-cytotoxicity","display_name":"complement-dependent cytotoxicity","score":0.8259999752044678},{"id":"https://openalex.org/keywords/antigen-absorption","display_name":"antigen absorption","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.8536655902862549},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6659231185913086},{"id":"https://openalex.org/C2780303067","wikidata":"https://www.wikidata.org/wiki/Q223099","display_name":"Methylcholanthrene","level":3,"score":0.6223633885383606},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5846289992332458},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5580896735191345},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.46741652488708496},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.4541480243206024},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4293321669101715},{"id":"https://openalex.org/C2779456560","wikidata":"https://www.wikidata.org/wiki/Q23488","display_name":"C57BL/6","level":2,"score":0.41683095693588257},{"id":"https://openalex.org/C3018646818","wikidata":"https://www.wikidata.org/wiki/Q420496","display_name":"Immune sera","level":3,"score":0.41503337025642395},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.39305031299591064},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.30677181482315063},{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.1088232696056366},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10453325510025024},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06468799710273743}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003165","descriptor_name":"Complement System Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003429","descriptor_name":"Cross Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008748","descriptor_name":"Methylcholanthrene","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013539","descriptor_name":"Simian virus 40","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.67.1.193","doi":"https://doi.org/10.1073/pnas.67.1.193","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.67.1.193","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:283187","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/283187","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:4318777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4318777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:mouseion.jax.org:ssbb1970-1201","doi":null,"is_oa":false,"landing_page_url":"https://mouseion.jax.org/ssbb1970/202","pdf_url":null,"source":{"id":"https://openalex.org/S4377196421","display_name":"The Mouseion at the JAXlibrary (Jackson Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115256","host_organization_name":"Jackson Laboratory","host_organization_lineage":["https://openalex.org/I4210115256"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Subject Strain Bibliography 1970","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:283187","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/283187","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320313780","display_name":"Lalor Foundation","ror":"https://ror.org/03vpdge44"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W628300856","https://openalex.org/W1488341157","https://openalex.org/W1605428934","https://openalex.org/W2004236800","https://openalex.org/W2019275827","https://openalex.org/W2020567063","https://openalex.org/W2024441285","https://openalex.org/W2029571231","https://openalex.org/W2032678095","https://openalex.org/W2038644016","https://openalex.org/W2038722446","https://openalex.org/W2041372181","https://openalex.org/W2042954723","https://openalex.org/W2055280853","https://openalex.org/W2071878806","https://openalex.org/W2072573978","https://openalex.org/W2082547962","https://openalex.org/W2101073592","https://openalex.org/W2328542833","https://openalex.org/W2410723883","https://openalex.org/W2411460421","https://openalex.org/W4246904433"],"related_works":["https://openalex.org/W7074008001","https://openalex.org/W1906927754","https://openalex.org/W117362816","https://openalex.org/W2292148277","https://openalex.org/W2079781570","https://openalex.org/W2395297257","https://openalex.org/W1482268231","https://openalex.org/W2088987941","https://openalex.org/W7098749460","https://openalex.org/W2037111172"],"abstract_inverted_index":{"Serum":[0],"obtained":[1,23,47],"from":[2,24,49],"guinea":[3],"pigs":[4],"immunized":[5],"with":[6,69],"unfertilized":[7],"C57BL/6":[8,65],"mouse":[9,78],"eggs":[10,22],"was":[11,32],"found":[12],"to":[13],"be":[14],"cytotoxic":[15,34,59],"in":[16],"the":[17],"presence":[18],"of":[19],"complement":[20],"for":[21,35,60,77],"syngeneic":[25,50],"and":[26,64],"allogeneic":[27,52],"mice.":[28,53],"The":[29,54],"anti-egg":[30,55,72],"serum":[31,56,73],"not":[33],"rat":[36],"eggs,":[37],"lymph":[38],"node":[39],"cells,":[40,43,71],"methylcholanthrene-induced":[41],"tumor":[42],"or":[44,51],"3T3":[45,62],"cells":[46,63],"either":[48],"was,":[57],"however,":[58],"SV40-transformed":[61,70],"cells.":[66],"After":[67],"absorption":[68],"lost":[74],"its":[75],"cytotoxicity":[76],"eggs.":[79]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}