{"id":"https://openalex.org/W1972425756","doi":"https://doi.org/10.1016/s1674-8301(11)60014-6","title":"A functional type I interferon pathway drives resistance to cornea herpes simplex virus type 1 infection by recruitment of leukocytes","display_name":"A functional type I interferon pathway drives resistance to cornea herpes simplex virus type 1 infection by recruitment of leukocytes","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W1972425756","doi":"https://doi.org/10.1016/s1674-8301(11)60014-6","mag":"1972425756","pmid":"https://pubmed.ncbi.nlm.nih.gov/21709805","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3119485"},"language":"en","primary_location":{"id":"doi:10.1016/s1674-8301(11)60014-6","doi":"https://doi.org/10.1016/s1674-8301(11)60014-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1674-8301(11)60014-6","pdf_url":null,"source":{"id":"https://openalex.org/S165426342","display_name":"Journal of Biomedical Research","issn_l":"1674-8301","issn":["1674-8301","2352-4685"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3119485","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010566352","display_name":"Christopher D. Conrady","orcid":"https://orcid.org/0000-0002-8531-0037","observed_orcids":["https://orcid.org/0000-0002-8531-0037"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher D. Conrady","raw_affiliation_strings":["Departments of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, 73104, USA","Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, 73104, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Heather Jones","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Jones","raw_affiliation_strings":["Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100706464","display_name":"Min Zheng","orcid":"https://orcid.org/0009-0003-9811-4937","observed_orcids":["https://orcid.org/0009-0003-9811-4937"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Min Zheng","raw_affiliation_strings":["Department of Ophthalmology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","institution_ids":["https://openalex.org/I49332381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037611291","display_name":"Daniel J.J. Carr","orcid":"https://orcid.org/0000-0003-1954-2478","observed_orcids":["https://orcid.org/0000-0003-1954-2478"]},"institutions":[{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel J.J. Carr","raw_affiliation_strings":["Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","Department of Ophthalmology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Immunology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Ophthalmology, The University of Oklahoma Health Science Center, Oklahoma City, OK, 73104, USA","institution_ids":["https://openalex.org/I49332381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037611291"],"corresponding_institution_ids":["https://openalex.org/I49332381"],"apc_list":null,"apc_paid":null,"fwci":1.845,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.83998021,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"25","issue":"2","first_page":"111","last_page":"119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-i-interferon","display_name":"type I interferon","score":0.9340000152587891},{"id":"https://openalex.org/keywords/interferon-alpha","display_name":"interferon-alpha","score":0.7990000247955322},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.984000027179718},{"id":"https://openalex.org/keywords/corneal-infection","display_name":"corneal infection","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ocular-herpes","display_name":"ocular herpes","score":0.656000018119812},{"id":"https://openalex.org/keywords/type-i-interferon-receptor","display_name":"type I interferon receptor","score":0.75},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.7670000195503235},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.9990000128746033},{"id":"https://openalex.org/keywords/t-cell-recruitment","display_name":"T cell recruitment","score":0.7630000114440918},{"id":"https://openalex.org/keywords/chemokine-production","display_name":"chemokine production","score":0.9459999799728394},{"id":"https://openalex.org/keywords/corneal-epithelial-cells","display_name":"corneal epithelial cells","score":0.878000020980835},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6420000195503235},{"id":"https://openalex.org/keywords/adaptive-immune-response","display_name":"adaptive immune response","score":0.8330000042915344},{"id":"https://openalex.org/keywords/mandibular-lymph-nodes","display_name":"mandibular lymph nodes","score":0.722000002861023},{"id":"https://openalex.org/keywords/virus-susceptibility","display_name":"viral susceptibility","score":0.45399999618530273}],"concepts":[{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.8156528472900391},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.6645209789276123},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6562930941581726},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.6371139287948608},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6275935173034668},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5598933696746826},{"id":"https://openalex.org/C17502307","wikidata":"https://www.wikidata.org/wiki/Q411999","display_name":"CXCL9","level":5,"score":0.5478857755661011},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5433311462402344},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4715069830417633},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.44935277104377747},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.44328102469444275},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.4224301874637604},{"id":"https://openalex.org/C5858377","wikidata":"https://www.wikidata.org/wiki/Q986112","display_name":"CXCL10","level":4,"score":0.37786930799484253},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/s1674-8301(11)60014-6","doi":"https://doi.org/10.1016/s1674-8301(11)60014-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1674-8301(11)60014-6","pdf_url":null,"source":{"id":"https://openalex.org/S165426342","display_name":"Journal of Biomedical Research","issn_l":"1674-8301","issn":["1674-8301","2352-4685"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3119485","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3119485","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biomed Res","raw_type":"Text"},{"id":"pmid:21709805","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21709805","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical research","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3119485","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3119485","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biomed Res","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3948148410","display_name":"Mentoring Vision Research In Oklahoma","funder_award_id":"P20RR017703","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G3996733508","display_name":"Molecular Basis of Immunity","funder_award_id":"T32AI007633","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5767302889","display_name":"The Neuroimmunology of Viral Infection","funder_award_id":"R01AI053108","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000887589","display_name":"P30 Center Core Grant for Vision Research","funder_award_id":"P30EY021725","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W86328080","https://openalex.org/W115589982","https://openalex.org/W169652639","https://openalex.org/W1523485980","https://openalex.org/W1541097619","https://openalex.org/W1589473146","https://openalex.org/W1642090213","https://openalex.org/W1645084893","https://openalex.org/W1833357512","https://openalex.org/W1893481266","https://openalex.org/W1918282372","https://openalex.org/W1963064194","https://openalex.org/W1968134447","https://openalex.org/W1981400752","https://openalex.org/W2004829503","https://openalex.org/W2013453300","https://openalex.org/W2028645756","https://openalex.org/W2037358732","https://openalex.org/W2038972698","https://openalex.org/W2045423123","https://openalex.org/W2047882003","https://openalex.org/W2055223113","https://openalex.org/W2059013205","https://openalex.org/W2073296110","https://openalex.org/W2087004183","https://openalex.org/W2091153004","https://openalex.org/W2092009940","https://openalex.org/W2093033018","https://openalex.org/W2094446542","https://openalex.org/W2094565610","https://openalex.org/W2095840406","https://openalex.org/W2101083359","https://openalex.org/W2103943058","https://openalex.org/W2105882438","https://openalex.org/W2108948157","https://openalex.org/W2113180936","https://openalex.org/W2125060130","https://openalex.org/W2129071472","https://openalex.org/W2133605770","https://openalex.org/W2134216634","https://openalex.org/W2134397718","https://openalex.org/W2134438797","https://openalex.org/W2139175652","https://openalex.org/W2150098469","https://openalex.org/W2155661903","https://openalex.org/W2157962615","https://openalex.org/W2158825435","https://openalex.org/W2160063406","https://openalex.org/W2165662544","https://openalex.org/W2167414261","https://openalex.org/W2169407070","https://openalex.org/W2345576086","https://openalex.org/W2610208464","https://openalex.org/W2992145912","https://openalex.org/W4313343438"],"related_works":["https://openalex.org/W4324065237","https://openalex.org/W2092009940","https://openalex.org/W2191592717","https://openalex.org/W2345576086","https://openalex.org/W2034106674","https://openalex.org/W2056398804","https://openalex.org/W7095121816","https://openalex.org/W2010905723","https://openalex.org/W2049797817","https://openalex.org/W1743570032"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}
