{"id":"https://openalex.org/W1972284136","doi":"https://doi.org/10.1016/j.jpba.2005.11.035","title":"Determination of clopidogrel metabolite (SR26334) in human plasma by LC\u2013MS","display_name":"Determination of clopidogrel metabolite (SR26334) in human plasma by LC\u2013MS","publication_year":2006,"publication_date":"2006-01-07","ids":{"openalex":"https://openalex.org/W1972284136","doi":"https://doi.org/10.1016/j.jpba.2005.11.035","mag":"1972284136","pmid":"https://pubmed.ncbi.nlm.nih.gov/16406450"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpba.2005.11.035","doi":"https://doi.org/10.1016/j.jpba.2005.11.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jpba.2005.11.035","pdf_url":null,"source":{"id":"https://openalex.org/S174893293","display_name":"Journal of Pharmaceutical and Biomedical Analysis","issn_l":"0731-7085","issn":["0731-7085","1873-264X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical and Biomedical Analysis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050186593","display_name":"Hanna Ksyci\u0144ska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160142","display_name":"Instytut Farmaceutyczny","ror":"https://ror.org/05695qy17","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210160142"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Hanna Ksycinska","raw_affiliation_strings":["Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland. hksycinska@op.pl","Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland. hksycinska@op.pl","institution_ids":["https://openalex.org/I4210160142"]},{"raw_affiliation_string":"Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland","institution_ids":["https://openalex.org/I4210160142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091573775","display_name":"Piotr J. Rudzki","orcid":"https://orcid.org/0000-0002-4622-4849","observed_orcids":["https://orcid.org/0000-0002-4622-4849"]},"institutions":[{"id":"https://openalex.org/I4210160142","display_name":"Instytut Farmaceutyczny","ror":"https://ror.org/05695qy17","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210160142"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Piotr Rudzki","raw_affiliation_strings":["Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland","institution_ids":["https://openalex.org/I4210160142"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081918982","display_name":"Miros\u0142awa Bukowska-Kiliszek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160142","display_name":"Instytut Farmaceutyczny","ror":"https://ror.org/05695qy17","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210160142"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Miros\u0142awa Bukowska-Kiliszek","raw_affiliation_strings":["Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Pharmaceutical Research Institute, 8 Rydygiera Street, 01-793 Warsaw, Poland","institution_ids":["https://openalex.org/I4210160142"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050186593"],"corresponding_institution_ids":["https://openalex.org/I4210160142"],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":3.9534,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.93322937,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"41","issue":"2","first_page":"533","last_page":"539"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.8593999743461609,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.8593999743461609,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.12020000070333481,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.8230000138282776},{"id":"https://openalex.org/keywords/clopidogrel-metabolite","display_name":"clopidogrel metabolite","score":0.925000011920929},{"id":"https://openalex.org/keywords/human-plasma","display_name":"human plasma","score":0.734000027179718},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.8109999895095825},{"id":"https://openalex.org/keywords/liquid-liquid-extraction","display_name":"liquid-liquid extraction","score":0.8209999799728394},{"id":"https://openalex.org/keywords/reversed-phase-hplc","display_name":"reversed-phase HPLC","score":0.6980000138282776},{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"mass spectrometry","score":0.6970000267028809},{"id":"https://openalex.org/keywords/internal-standard","display_name":"internal standard","score":0.7749999761581421},{"id":"https://openalex.org/keywords/drug-quantification","display_name":"pharmaceutical analysis","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9329297542572021},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.8763225674629211},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.7490003108978271},{"id":"https://openalex.org/C2777379063","wikidata":"https://www.wikidata.org/wiki/Q161233","display_name":"Formic acid","level":2,"score":0.6484265327453613},{"id":"https://openalex.org/C23531484","wikidata":"https://www.wikidata.org/wiki/Q3196863","display_name":"Calibration curve","level":3,"score":0.6132089495658875},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5674895644187927},{"id":"https://openalex.org/C81426234","wikidata":"https://www.wikidata.org/wiki/Q1408763","display_name":"Solid phase extraction","level":3,"score":0.5208107233047485},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.49747517704963684},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.47346654534339905},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.45013466477394104},{"id":"https://openalex.org/C2776108993","wikidata":"https://www.wikidata.org/wiki/Q866399","display_name":"Liquid\u2013liquid extraction","level":3,"score":0.42498964071273804},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.05999100208282471},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004355","descriptor_name":"Drug Stability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jpba.2005.11.035","doi":"https://doi.org/10.1016/j.jpba.2005.11.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jpba.2005.11.035","pdf_url":null,"source":{"id":"https://openalex.org/S174893293","display_name":"Journal of Pharmaceutical and Biomedical Analysis","issn_l":"0731-7085","issn":["0731-7085","1873-264X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical and Biomedical Analysis","raw_type":"journal-article"},{"id":"pmid:16406450","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16406450","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmaceutical and biomedical analysis","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1515542254","https://openalex.org/W1996587391","https://openalex.org/W2014455125","https://openalex.org/W2021880542","https://openalex.org/W2030370251","https://openalex.org/W2039496408","https://openalex.org/W2046852461","https://openalex.org/W2124231871","https://openalex.org/W2405379010"],"related_works":["https://openalex.org/W2379647730","https://openalex.org/W2075061037","https://openalex.org/W2014455125","https://openalex.org/W2351821058","https://openalex.org/W2383321437","https://openalex.org/W2133455015","https://openalex.org/W2104814383","https://openalex.org/W1973913628","https://openalex.org/W2061796344","https://openalex.org/W2038454584"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}