{"id":"https://openalex.org/W1972254403","doi":"https://doi.org/10.1016/s0378-4347(00)84281-4","title":"Liquid chromatographic determination of caffeine in biologic fluids","display_name":"Liquid chromatographic determination of caffeine in biologic fluids","publication_year":1982,"publication_date":"1982-05-01","ids":{"openalex":"https://openalex.org/W1972254403","doi":"https://doi.org/10.1016/s0378-4347(00)84281-4","mag":"1972254403","pmid":"https://pubmed.ncbi.nlm.nih.gov/7096473"},"language":"en","primary_location":{"id":"doi:10.1016/s0378-4347(00)84281-4","doi":"https://doi.org/10.1016/s0378-4347(00)84281-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-4347(00)84281-4","pdf_url":null,"source":{"id":"https://openalex.org/S14366386","display_name":"Journal of Chromatography B Biomedical Sciences and Applications","issn_l":"0378-4347","issn":["0378-4347","1387-2273","1872-812X","1878-5603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B: Biomedical Sciences and Applications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023131297","display_name":"David B. Haughey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Haughey","raw_affiliation_strings":["Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111615387","display_name":"Richard M. Greenberg","orcid":"https://orcid.org/0000-0002-8792-3005","observed_orcids":["https://orcid.org/0000-0002-8792-3005"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Greenberg","raw_affiliation_strings":["Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090047278","display_name":"Stephen F. Schaal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen F. Schaal","raw_affiliation_strings":["Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108423726","display_name":"John J. Lima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John J. Lima","raw_affiliation_strings":["Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, 500 W. 12th Avenue, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Pharmacy Practice, College of Pharmacy, and Division of Cardiology, College of Medicine, Ohio State University, Columbus, OH 43210 U.S.A","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I52357470"],"apc_list":null,"apc_paid":null,"fwci":4.4604,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.94315888,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"229","issue":"2","first_page":"387","last_page":"395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.8199999928474426},{"id":"https://openalex.org/keywords/caffeine-determination","display_name":"caffeine determination","score":0.7319999933242798},{"id":"https://openalex.org/keywords/body-fluids","display_name":"biological fluids","score":0.902999997138977},{"id":"https://openalex.org/keywords/serum","display_name":"serum","score":0.7639999985694885},{"id":"https://openalex.org/keywords/saliva","display_name":"saliva","score":0.9980000257492065},{"id":"https://openalex.org/keywords/coffee","display_name":"coffee","score":0.7929999828338623},{"id":"https://openalex.org/keywords/caffeine-metabolites","display_name":"caffeine metabolites","score":0.7319999933242798},{"id":"https://openalex.org/keywords/xanthine","display_name":"xanthine","score":0.984000027179718},{"id":"https://openalex.org/keywords/caffeine-pharmacokinetics","display_name":"caffeine pharmacokinetics","score":0.8960000276565552}],"concepts":[{"id":"https://openalex.org/C2778500429","wikidata":"https://www.wikidata.org/wiki/Q60235","display_name":"Caffeine","level":2,"score":0.9859100580215454},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.8398340940475464},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.8157588243484497},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7315188646316528},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.5885993242263794},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.500861644744873},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2504695653915405},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.15377143025398254},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11587291955947876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09287947416305542}],"mesh":[{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003069","descriptor_name":"Coffee","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0378-4347(00)84281-4","doi":"https://doi.org/10.1016/s0378-4347(00)84281-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-4347(00)84281-4","pdf_url":null,"source":{"id":"https://openalex.org/S14366386","display_name":"Journal of Chromatography B Biomedical Sciences and Applications","issn_l":"0378-4347","issn":["0378-4347","1387-2273","1872-812X","1878-5603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B: Biomedical Sciences and Applications","raw_type":"journal-article"},{"id":"pmid:7096473","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7096473","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chromatography","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W166333077","https://openalex.org/W1921297128","https://openalex.org/W1990844809","https://openalex.org/W2001420919","https://openalex.org/W2016233146","https://openalex.org/W2024483071","https://openalex.org/W2038556136","https://openalex.org/W2039691276","https://openalex.org/W2052044420","https://openalex.org/W2064439460","https://openalex.org/W2065284240","https://openalex.org/W2086360687","https://openalex.org/W2124734188","https://openalex.org/W2328867190","https://openalex.org/W2337160971","https://openalex.org/W2472976730"],"related_works":["https://openalex.org/W2948380785","https://openalex.org/W1968362740","https://openalex.org/W2023723680","https://openalex.org/W2396262664","https://openalex.org/W2001030316","https://openalex.org/W2054447553","https://openalex.org/W293113457","https://openalex.org/W2319094516","https://openalex.org/W1973308834","https://openalex.org/W1987719727"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}