{"id":"https://openalex.org/W1972228166","doi":"https://doi.org/10.1074/jbc.m803934200","title":"Defective Dissociation of a \u201cSlow\u201d RecA Mutant Protein Imparts an Escherichia coli Growth Defect","display_name":"Defective Dissociation of a \u201cSlow\u201d RecA Mutant Protein Imparts an Escherichia coli Growth Defect","publication_year":2008,"publication_date":"2008-07-05","ids":{"openalex":"https://openalex.org/W1972228166","doi":"https://doi.org/10.1074/jbc.m803934200","mag":"1972228166","pmid":"https://pubmed.ncbi.nlm.nih.gov/18603529","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2529011"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m803934200","doi":"https://doi.org/10.1074/jbc.m803934200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m803934200","pdf_url":"http://www.jbc.org/article/S0021925819492363/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jbc.org/article/S0021925819492363/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Julia M. Cox","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia M. Cox","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100348623","display_name":"Hao Li","orcid":"https://orcid.org/0000-0002-6652-4793","observed_orcids":["https://orcid.org/0000-0002-6652-4793"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hao Li","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009865471","display_name":"Elizabeth Anne Wood","orcid":"https://orcid.org/0000-0002-7769-8481","observed_orcids":["https://orcid.org/0000-0002-7769-8481"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth A. Wood","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041118769","display_name":"Sindhu Chitteni\u2010Pattu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sindhu Chitteni-Pattu","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103530578","display_name":"Ross B. Inman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ross B. Inman","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080771015","display_name":"Michael Matthew Cox","orcid":"https://orcid.org/0000-0003-3606-5722","observed_orcids":["https://orcid.org/0000-0003-3606-5722"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael M. Cox","raw_affiliation_strings":["Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706-1544","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080771015"],"corresponding_institution_ids":["https://openalex.org/I135310074"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":0.548,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.63045382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"283","issue":"36","first_page":"24909","last_page":"24921"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reca","display_name":"RecA","score":0.9129999876022339},{"id":"https://openalex.org/keywords/atp-hydrolysis","display_name":"ATP hydrolysis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/dna-strand-exchange","display_name":"DNA strand exchange","score":0.9909999966621399},{"id":"https://openalex.org/keywords/stalled-replication-forks","display_name":"stalled replication forks","score":0.7260000109672546},{"id":"https://openalex.org/keywords/recombinational-dna-repair","display_name":"recombinational DNA repair","score":0.9150000214576721},{"id":"https://openalex.org/keywords/bacterial-growth-defects","display_name":"bacterial growth defects","score":0.8309999704360962},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8349999785423279},{"id":"https://openalex.org/keywords/suppressors","display_name":"suppressors","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C141315368","wikidata":"https://www.wikidata.org/wiki/Q4654881","display_name":"ATP hydrolysis","level":4,"score":0.7849821448326111},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5385023951530457},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5315765142440796},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.4937487542629242},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.4804058372974396},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.47588005661964417},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46813663840293884},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4654660224914551},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3946385383605957},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35216718912124634},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.187555193901062},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.16748839616775513},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.097680002450943}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011938","descriptor_name":"Rec A Recombinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011938","descriptor_name":"Rec A Recombinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1074/jbc.m803934200","doi":"https://doi.org/10.1074/jbc.m803934200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m803934200","pdf_url":"http://www.jbc.org/article/S0021925819492363/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2529011","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2529011","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biol Chem","raw_type":"Text"},{"id":"pmid:18603529","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18603529","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m803934200","doi":"https://doi.org/10.1074/jbc.m803934200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m803934200","pdf_url":"http://www.jbc.org/article/S0021925819492363/pdf","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G637704490","display_name":null,"funder_award_id":"GM32335","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7165872653","display_name":"Mechanisms and applications of recombinational DNA repair","funder_award_id":"U01GM032335","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7399874518","display_name":"The Biochemistry of Genetic Recombination/RecA Protein","funder_award_id":"R01GM032335","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000243287","display_name":null,"funder_award_id":"GM32335","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309434","display_name":"University of Wisconsin-Madison","ror":"https://ror.org/01y2jtd41"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1972228166.pdf","grobid_xml":"https://content.openalex.org/works/W1972228166.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1484036744","https://openalex.org/W1493386189","https://openalex.org/W1503969832","https://openalex.org/W1520909561","https://openalex.org/W1524885316","https://openalex.org/W1531198323","https://openalex.org/W1540750107","https://openalex.org/W1559132509","https://openalex.org/W1570361288","https://openalex.org/W1573374536","https://openalex.org/W1582323028","https://openalex.org/W1591999606","https://openalex.org/W1600533038","https://openalex.org/W1978955797","https://openalex.org/W1982003972","https://openalex.org/W1989950632","https://openalex.org/W1990010457","https://openalex.org/W1994338971","https://openalex.org/W1998449586","https://openalex.org/W2000826427","https://openalex.org/W2003103656","https://openalex.org/W2003239553","https://openalex.org/W2003956909","https://openalex.org/W2005548481","https://openalex.org/W2006041183","https://openalex.org/W2007343241","https://openalex.org/W2011659166","https://openalex.org/W2021984369","https://openalex.org/W2022001195","https://openalex.org/W2024480366","https://openalex.org/W2029026026","https://openalex.org/W2031595067","https://openalex.org/W2036842869","https://openalex.org/W2037222730","https://openalex.org/W2040092826","https://openalex.org/W2041025611","https://openalex.org/W2041817089","https://openalex.org/W2043141017","https://openalex.org/W2043335148","https://openalex.org/W2046811539","https://openalex.org/W2066616729","https://openalex.org/W2072669896","https://openalex.org/W2073483885","https://openalex.org/W2074273508","https://openalex.org/W2075909368","https://openalex.org/W2077535486","https://openalex.org/W2079817946","https://openalex.org/W2084142731","https://openalex.org/W2084802036","https://openalex.org/W2086581740","https://openalex.org/W2093398311","https://openalex.org/W2098865666","https://openalex.org/W2114809602","https://openalex.org/W2114965792","https://openalex.org/W2124037827","https://openalex.org/W2125119079","https://openalex.org/W2131574750","https://openalex.org/W2133279612","https://openalex.org/W2133290100","https://openalex.org/W2139486841","https://openalex.org/W2139925979","https://openalex.org/W2142168955","https://openalex.org/W2142822333","https://openalex.org/W2143669599","https://openalex.org/W2152392747","https://openalex.org/W2168211826","https://openalex.org/W2169118588","https://openalex.org/W2170455802"],"related_works":["https://openalex.org/W2267923574","https://openalex.org/W3167723294","https://openalex.org/W2037222730","https://openalex.org/W2598845379","https://openalex.org/W623818837","https://openalex.org/W2114965792","https://openalex.org/W1601654483","https://openalex.org/W2022559772","https://openalex.org/W1531198323","https://openalex.org/W1540831008"],"abstract_inverted_index":{"The":[0,76,113,152],"RecA":[1,36,81,132,142,170,189,210],"and":[2,23,31,62,125,181],"some":[3],"related":[4],"proteins":[5],"possess":[6],"a":[7,119,130,138,205,213,231],"simple":[8],"motif,":[9],"called":[10],"(KR)X(KR),":[11],"that":[12,164,185,200,222],"(in":[13,70],"RecA)":[14],"consists":[15],"of":[16,52,59,96,110,118,146,169,230],"two":[17],"lysine":[18],"residues":[19],"at":[20,25,171],"positions":[21],"248":[22],"250":[24],"the":[26,39,48,57,65,97,108,116,144,147,165,192,197,218,227],"subunit-subunit":[27],"interface.":[28],"This":[29],"study":[30],"previous":[32],"work":[33,69],"implicate":[34],"this":[35,71],"motif":[37],"in":[38,45,137,158,208,217],"following:":[40],"(a)":[41],"catalyzing":[42],"ATP":[43,49,60,66,88,111,123],"hydrolysis":[44,67,89,124],"trans,(b)":[46],"coordinating":[47],"hydrolytic":[50],"cycles":[51],"adjacent":[53],"subunits,":[54],"(c)":[55],"governing":[56],"rate":[58,109,229],"hydrolysis,":[61],"(d)":[63],"coupling":[64,121],"to":[68,92],"case":[72],"DNA":[73,100,126,202],"strand":[74,101,127],"exchange).":[75],"conservative":[77],"K250R":[78,133,190],"mutation":[79],"leaves":[80],"nucleoprotein":[82],"filament":[83],"formation":[84],"largely":[85],"intact.":[86],"However,":[87],"is":[90,103,135,149,156,204],"slowed":[91,105],"less":[93],"than":[94],"15%":[95],"wild-type":[98],"rate.":[99],"exchange":[102],"also":[104],"commensurate":[106],"with":[107],"hydrolysis.":[112],"results":[114,198],"reinforce":[115],"idea":[117],"tight":[120],"between":[122],"exchange.":[128],"When":[129],"plasmid-borne":[131],"protein":[134,211],"expressed":[136],"cell":[139,220],"otherwise":[140],"lacking":[141,160],"protein,":[143],"growth":[145,154,194,228],"cells":[148,159],"severely":[150],"curtailed.":[151],"slow":[153,193],"defect":[155,166],"alleviated":[157],"RecFOR":[161],"function,":[162],"suggesting":[163],"reflects":[167],"loading":[168],"stalled":[172],"replication":[173],"forks.":[174],"Suppressors":[175],"occur":[176],"as":[177],"recA":[178],"gene":[179],"alterations,":[180],"their":[182],"properties":[183,224],"indicate":[184],"limited":[186],"dissociation":[187],"by":[188],"confers":[191],"phenotype.":[195],"Overall,":[196],"suggest":[199],"recombinational":[201],"repair":[203],"common":[206],"occurrence":[207],"cells.":[209],"plays":[212],"sufficiently":[214],"intimate":[215],"role":[216],"bacterial":[219,232],"cycle":[221],"its":[223],"can":[225],"limit":[226],"culture.":[233]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}