{"id":"https://openalex.org/W1972115754","doi":"https://doi.org/10.1097/00132576-200406000-00002","title":"Treatment of Opiate Addicts With Buprenorphine","display_name":"Treatment of Opiate Addicts With Buprenorphine","publication_year":2004,"publication_date":"2004-05-26","ids":{"openalex":"https://openalex.org/W1972115754","doi":"https://doi.org/10.1097/00132576-200406000-00002","mag":"1972115754"},"language":"en","primary_location":{"id":"doi:10.1097/00132576-200406000-00002","doi":"https://doi.org/10.1097/00132576-200406000-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00132576-200406000-00002","pdf_url":null,"source":{"id":"https://openalex.org/S50600419","display_name":"Addictive Disorders & Their Treatment","issn_l":"1531-5754","issn":["1531-5754","1535-1122"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addictive Disorders & Their Treatment","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073079083","display_name":"Uwe Verthein","orcid":"https://orcid.org/0000-0002-5565-5536","observed_orcids":["https://orcid.org/0000-0002-5565-5536"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Uwe Verthein","raw_affiliation_strings":["the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","Supported by ESSEX Pharma GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Supported by ESSEX Pharma GmbH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083203073","display_name":"Michael Prinzleve","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Prinzleve","raw_affiliation_strings":["the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","Supported by ESSEX Pharma GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Supported by ESSEX Pharma GmbH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026227597","display_name":"Georg Farnbacher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Georg Farnbacher","raw_affiliation_strings":["the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","Supported by ESSEX Pharma GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Supported by ESSEX Pharma GmbH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111535683","display_name":"Christian Haasen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Haasen","raw_affiliation_strings":["the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","Supported by ESSEX Pharma GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Supported by ESSEX Pharma GmbH","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067159385","display_name":"Michael Reinhardt Krausz","orcid":"https://orcid.org/0000-0002-3509-7274","observed_orcids":["https://orcid.org/0000-0002-3509-7274"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Krausz","raw_affiliation_strings":["the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","Supported by ESSEX Pharma GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"From the Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Reprints: Dr. Uwe Verthein, Centre for Interdisciplinary Addiction Research (ZIS), Psychiatric Clinic, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg (e-mail: [email\u00a0protected])","institution_ids":["https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Supported by ESSEX Pharma GmbH","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5073079083"],"corresponding_institution_ids":["https://openalex.org/I4210108711"],"apc_list":null,"apc_paid":null,"fwci":0.3641,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.67945572,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"3","issue":"2","first_page":"58","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/buprenorphine","display_name":"buprenorphine","score":1.0},{"id":"https://openalex.org/keywords/opioid-use-disorder","display_name":"opioid use disorder","score":0.8740000128746033},{"id":"https://openalex.org/keywords/medication-assisted-treatment","display_name":"medication-assisted treatment","score":0.9700000286102295},{"id":"https://openalex.org/keywords/methadone-maintenance-treatment","display_name":"methadone maintenance treatment","score":0.7739999890327454},{"id":"https://openalex.org/keywords/withdrawal-symptoms","display_name":"withdrawal symptoms","score":0.8939999938011169},{"id":"https://openalex.org/keywords/drug-use-behavior","display_name":"drug use behavior","score":0.7739999890327454},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.625},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.953000009059906},{"id":"https://openalex.org/keywords/general-practitioners","display_name":"general practitioners","score":0.6919999718666077},{"id":"https://openalex.org/keywords/post-marketing-surveillance","display_name":"post-marketing surveillance","score":0.9710000157356262}],"concepts":[{"id":"https://openalex.org/C2778949969","wikidata":"https://www.wikidata.org/wiki/Q407721","display_name":"Buprenorphine","level":4,"score":0.9179484844207764},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8120662569999695},{"id":"https://openalex.org/C2778140631","wikidata":"https://www.wikidata.org/wiki/Q2026938","display_name":"Opiate","level":3,"score":0.7382125854492188},{"id":"https://openalex.org/C2778767360","wikidata":"https://www.wikidata.org/wiki/Q179996","display_name":"Methadone","level":2,"score":0.6430793404579163},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.6394139528274536},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.4298044443130493},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.34572523832321167},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26794958114624023},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.2165268361568451},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.11039137840270996},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00132576-200406000-00002","doi":"https://doi.org/10.1097/00132576-200406000-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00132576-200406000-00002","pdf_url":null,"source":{"id":"https://openalex.org/S50600419","display_name":"Addictive Disorders & Their Treatment","issn_l":"1531-5754","issn":["1531-5754","1535-1122"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addictive Disorders & Their Treatment","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W125827253","https://openalex.org/W1973849525","https://openalex.org/W1978946510","https://openalex.org/W1979184030","https://openalex.org/W1980315117","https://openalex.org/W1992389336","https://openalex.org/W1998425896","https://openalex.org/W2002091306","https://openalex.org/W2007802571","https://openalex.org/W2027873427","https://openalex.org/W2029472930","https://openalex.org/W2034202363","https://openalex.org/W2038802102","https://openalex.org/W2044053502","https://openalex.org/W2048376222","https://openalex.org/W2049853347","https://openalex.org/W2061161214","https://openalex.org/W2063539450","https://openalex.org/W2078592976","https://openalex.org/W2083263555","https://openalex.org/W2092356971","https://openalex.org/W2094064004","https://openalex.org/W2108791771","https://openalex.org/W2108978934","https://openalex.org/W2113517664","https://openalex.org/W2124503010","https://openalex.org/W2133801459","https://openalex.org/W2141882410","https://openalex.org/W2304131176"],"related_works":["https://openalex.org/W1976869578","https://openalex.org/W1999182319","https://openalex.org/W2040661175","https://openalex.org/W2126745806","https://openalex.org/W2466655546","https://openalex.org/W2077784683","https://openalex.org/W7094046309","https://openalex.org/W2003905787","https://openalex.org/W163375770","https://openalex.org/W1979184030"],"abstract_inverted_index":{"Aims:":[0],"In":[1],"a":[2,26,31,85,172],"nationwide":[3],"German":[4],"post-marketing":[5],"surveillance,":[6],"the":[7,44,102,112,137,141,146,152,182],"acceptance,":[8],"efficacy,":[9],"and":[10,41,48,53,71,91,130,151],"tolerability":[11],"of":[12,33,46,80,88,114,123,136,148,154,186],"buprenorphine":[13,125,164],"in":[14,101,160,181],"opiate":[15,94,187],"dependent":[16],"patients":[17,42,65,99,110,138,161],"were":[18,37,66,84,106],"tested.":[19],"Design:":[20],"The":[21,57,64,117],"study":[22,58],"was":[23,59],"conceived":[24],"as":[25],"prospective":[27],"naturalistic":[28],"approach":[29],"over":[30],"period":[32],"12":[34,54],"weeks.":[35,55],"Data":[36],"collected":[38],"from":[39,108],"doctors":[40],"at":[43,111],"start":[45],"treatment":[47,168,185],"after":[49],"1,":[50],"5,":[51],"9":[52],"Setting:":[56],"conducted":[60],"with":[61],"general":[62],"practitioners.":[63],"recruited":[67],"between":[68],"February":[69],"2000":[70],"April":[72],"2001.":[73],"Participants:":[74],"Inclusion":[75],"criteria":[76],"according":[77],"to":[78,170],"Summary":[79],"Product":[81],"Information":[82],"(SPC)":[83],"minimum":[86],"age":[87],"18":[89],"years":[90],"an":[92],"established":[93],"dependency.":[95,188],"Three":[96],"hundred":[97],"ninety":[98],"participated":[100],"study;":[103],"valid":[104],"data":[105],"available":[107],"314":[109],"time":[113],"inclusion.":[115],"Measurements:":[116],"descriptive":[118],"analysis":[119],"focused":[120],"on":[121],"duration":[122],"participation,":[124],"dosage,":[126],"drug":[127,149],"use":[128,150],"behavior,":[129],"withdrawal":[131,155],"symptoms.":[132],"Findings:":[133],"Sixty-eight":[134],"percent":[135],"regularly":[139],"completed":[140],"study.":[142],"Positive":[143],"effects":[144],"concerning":[145],"reduction":[147],"improvement":[153],"symptoms":[156],"can":[157],"be":[158,171],"observed":[159],"who":[162],"continued":[163],"treatment.":[165],"Conclusions:":[166],"Buprenorphine":[167],"proves":[169],"good":[173],"supplement":[174],"or":[175],"alternative":[176],"(for":[177],"methadone":[178],"maintenance":[179],"treatment)":[180],"medication":[183],"assisted":[184]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}