{"id":"https://openalex.org/W1972039113","doi":"https://doi.org/10.1016/j.ajo.2010.04.028","title":"Cardiovascular Risk Factors, Inflammation, and Corneal Arcus: The Singapore Malay Eye Study","display_name":"Cardiovascular Risk Factors, Inflammation, and Corneal Arcus: The Singapore Malay Eye Study","publication_year":2010,"publication_date":"2010-07-14","ids":{"openalex":"https://openalex.org/W1972039113","doi":"https://doi.org/10.1016/j.ajo.2010.04.028","mag":"1972039113","pmid":"https://pubmed.ncbi.nlm.nih.gov/20630492"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajo.2010.04.028","doi":"https://doi.org/10.1016/j.ajo.2010.04.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajo.2010.04.028","pdf_url":null,"source":{"id":"https://openalex.org/S50016660","display_name":"American Journal of Ophthalmology","issn_l":"0002-9394","issn":["0002-9394","1879-1891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075162983","display_name":"Renyi Wu","orcid":"https://orcid.org/0000-0002-5945-0124","observed_orcids":["https://orcid.org/0000-0002-5945-0124"]},"institutions":[{"id":"https://openalex.org/I2799299286","display_name":"Singapore National Eye Center","ror":"https://ror.org/029nvrb94","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2799299286"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Renyi Wu","raw_affiliation_strings":["Singapore Eye Research Institute, Singapore National Eye Centre, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore National Eye Centre, Singapore","institution_ids":["https://openalex.org/I2799299286","https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047012718","display_name":"Jie Jin Wang","orcid":"https://orcid.org/0000-0001-9491-4898","observed_orcids":["https://orcid.org/0000-0001-9491-4898"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105949","display_name":"Centre for Eye Research Australia","ror":"https://ror.org/01sqdef20","country_code":"AU","type":"facility","lineage":["https://openalex.org/I4210105949"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jie Jin Wang","raw_affiliation_strings":["Centre for Eye Research Australia, University of Melbourne, Australia","Centre for Vision Research, University of Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Eye Research Australia, University of Melbourne, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210105949"]},{"raw_affiliation_string":"Centre for Vision Research, University of Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049068947","display_name":"E Shyong Tai","orcid":"https://orcid.org/0000-0003-2929-8966","observed_orcids":["https://orcid.org/0000-0003-2929-8966"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"E. Shyong Tai","raw_affiliation_strings":["Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072258594","display_name":"Tien Yin Wong","orcid":"https://orcid.org/0000-0002-8448-1264","observed_orcids":["https://orcid.org/0000-0002-8448-1264"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I2799299286","display_name":"Singapore National Eye Center","ror":"https://ror.org/029nvrb94","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2799299286"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Tien Yin Wong","raw_affiliation_strings":["Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore","Singapore Eye Research Institute, Singapore National Eye Centre, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore Eye Research Institute, Singapore National Eye Centre, Singapore","institution_ids":["https://openalex.org/I2799299286","https://openalex.org/I4210116917"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5072258594"],"corresponding_institution_ids":["https://openalex.org/I165932596","https://openalex.org/I2799299286","https://openalex.org/I4210116917"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":null,"fwci":1.0119,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.77458682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"150","issue":"4","first_page":"581","last_page":"587.e1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7973999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7973999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.08730000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corneal-arcus","display_name":"corneal arcus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.9860000014305115},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.9139999747276306},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9950000047683716},{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.9710000157356262},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":1.0},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.6349999904632568},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.6959999799728394},{"id":"https://openalex.org/keywords/malay-adults","display_name":"Malay adults","score":0.7239999771118164},{"id":"https://openalex.org/keywords/asian-populations","display_name":"Asian populations","score":0.7850000262260437},{"id":"https://openalex.org/keywords/singapore-malay-eye-study","display_name":"Singapore Malay Eye Study","score":0.7799999713897705}],"concepts":[{"id":"https://openalex.org/C2776938241","wikidata":"https://www.wikidata.org/wiki/Q9237","display_name":"Malay","level":2,"score":0.7711043357849121},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6827107071876526},{"id":"https://openalex.org/C2909898526","wikidata":"https://www.wikidata.org/wiki/Q757838","display_name":"Corneal inflammation","level":3,"score":0.6613596081733704},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.6109515428543091},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5140501260757446},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.4246102571487427},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.39430367946624756},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19842582941055298},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000210","descriptor_name":"Acute-Phase Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000869","descriptor_name":"Anterior Eye Segment","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001112","descriptor_name":"Arcus Senilis","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012846","descriptor_name":"Singapore","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ajo.2010.04.028","doi":"https://doi.org/10.1016/j.ajo.2010.04.028","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajo.2010.04.028","pdf_url":null,"source":{"id":"https://openalex.org/S50016660","display_name":"American Journal of Ophthalmology","issn_l":"0002-9394","issn":["0002-9394","1879-1891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Ophthalmology","raw_type":"journal-article"},{"id":"pmid:20630492","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20630492","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of ophthalmology","raw_type":"Journal Article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/108284","doi":null,"is_oa":false,"landing_page_url":"http://scholarbank.nus.edu.sg/handle/10635/108284","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2675159349","display_name":null,"funder_award_id":"501/1/25-5","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"},{"id":"https://openalex.org/G2974830252","display_name":null,"funder_award_id":"0863/2004","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"},{"id":"https://openalex.org/G5009778109","display_name":null,"funder_award_id":"CSI/0002/2005","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"},{"id":"https://openalex.org/G7232005456","display_name":null,"funder_award_id":"0796/2003","funder_id":"https://openalex.org/F4320334737","funder_display_name":"National Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320320697","display_name":"Ministry of Health -Singapore","ror":"https://ror.org/00mrhvv69"},{"id":"https://openalex.org/F4320334737","display_name":"National Medical Research Council","ror":"https://ror.org/04x3cxs03"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1855998022","https://openalex.org/W1856081209","https://openalex.org/W1976432291","https://openalex.org/W1981618554","https://openalex.org/W1982956058","https://openalex.org/W1983022133","https://openalex.org/W2026618174","https://openalex.org/W2036790724","https://openalex.org/W2043470783","https://openalex.org/W2052882363","https://openalex.org/W2053971332","https://openalex.org/W2058709767","https://openalex.org/W2059177555","https://openalex.org/W2071554314","https://openalex.org/W2073520183","https://openalex.org/W2075936775","https://openalex.org/W2081040499","https://openalex.org/W2082525813","https://openalex.org/W2088913874","https://openalex.org/W2102576263","https://openalex.org/W2103731374","https://openalex.org/W2108986293","https://openalex.org/W2119635674","https://openalex.org/W2121915155","https://openalex.org/W2150917640","https://openalex.org/W2152875397","https://openalex.org/W2153402533","https://openalex.org/W2155933492","https://openalex.org/W2166370747","https://openalex.org/W2168889968","https://openalex.org/W2199339317","https://openalex.org/W2332022697","https://openalex.org/W2410326962","https://openalex.org/W3000563840"],"related_works":["https://openalex.org/W2036790724","https://openalex.org/W1992580301","https://openalex.org/W2001101391","https://openalex.org/W2088913874","https://openalex.org/W2332022697","https://openalex.org/W2785635494","https://openalex.org/W2750880285","https://openalex.org/W4417501914","https://openalex.org/W1976432291","https://openalex.org/W2082525813"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}