{"id":"https://openalex.org/W1971871007","doi":"https://doi.org/10.1159/000051448","title":"Operative vs. Nonoperative Therapy in Necrotizing Pancreatitis","display_name":"Operative vs. Nonoperative Therapy in Necrotizing Pancreatitis","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W1971871007","doi":"https://doi.org/10.1159/000051448","mag":"1971871007","pmid":"https://pubmed.ncbi.nlm.nih.gov/10026426"},"language":"en","primary_location":{"id":"doi:10.1159/000051448","doi":"https://doi.org/10.1159/000051448","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000051448","pdf_url":null,"source":{"id":"https://openalex.org/S28092622","display_name":"Digestion","issn_l":"0012-2823","issn":["0012-2823","1421-9867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestion","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111475583","display_name":"E. L. Bradley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157091","display_name":"Buffalo General Medical Center","ror":"https://ror.org/04ngv0f69","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1325611130","https://openalex.org/I4210157091"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"EdwardL. Bradley,III","raw_affiliation_strings":["Department of Surgery, Buffalo General Hospital, Buffalo, NY 14203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Buffalo General Hospital, Buffalo, NY 14203, USA","institution_ids":["https://openalex.org/I4210157091"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111475583"],"corresponding_institution_ids":["https://openalex.org/I4210157091"],"apc_list":null,"apc_paid":null,"fwci":2.8055,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.89696254,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"60","issue":"Suppl. 1","first_page":"19","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/necrotizing-pancreatitis","display_name":"necrotizing pancreatitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sterile-pancreatic-necrosis","display_name":"sterile pancreatic necrosis","score":0.8560000061988831},{"id":"https://openalex.org/keywords/infected-pancreatic-necrosis","display_name":"infected pancreatic necrosis","score":0.9729999899864197},{"id":"https://openalex.org/keywords/conservative-treatment","display_name":"conservative treatment","score":0.9049999713897705},{"id":"https://openalex.org/keywords/surgical-debridement","display_name":"surgical debridement","score":0.9769999980926514},{"id":"https://openalex.org/keywords/secondary-infection","display_name":"secondary infection","score":0.5429999828338623},{"id":"https://openalex.org/keywords/postoperative-drainage","display_name":"postoperative drainage","score":0.6549999713897705},{"id":"https://openalex.org/keywords/closed-drainage","display_name":"closed drainage","score":0.8050000071525574},{"id":"https://openalex.org/keywords/re-exploration","display_name":"re-exploration","score":0.8600000143051147},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.4180000126361847},{"id":"https://openalex.org/keywords/organ-failure","display_name":"organ failure","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.918471097946167},{"id":"https://openalex.org/C2777438270","wikidata":"https://www.wikidata.org/wiki/Q5248564","display_name":"Debridement (dental)","level":2,"score":0.8664103746414185},{"id":"https://openalex.org/C2910062394","wikidata":"https://www.wikidata.org/wiki/Q854573","display_name":"Necrotizing pancreatitis","level":3,"score":0.8543858528137207},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.746449887752533},{"id":"https://openalex.org/C2776670229","wikidata":"https://www.wikidata.org/wiki/Q854573","display_name":"Acute pancreatitis","level":2,"score":0.6562235951423645},{"id":"https://openalex.org/C3019207691","wikidata":"https://www.wikidata.org/wiki/Q1270448","display_name":"Surgical debridement","level":2,"score":0.6018657684326172},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.5589174032211304},{"id":"https://openalex.org/C2775967933","wikidata":"https://www.wikidata.org/wiki/Q1527888","display_name":"Pancreatitis","level":2,"score":0.5307058691978455},{"id":"https://openalex.org/C3020397523","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrotic tissue","level":2,"score":0.44928717613220215},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08564987778663635}],"mesh":[{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003646","descriptor_name":"Debridement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004322","descriptor_name":"Drainage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009102","descriptor_name":"Multiple Organ Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009102","descriptor_name":"Multiple Organ Failure","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019283","descriptor_name":"Pancreatitis, Acute Necrotizing","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D019283","descriptor_name":"Pancreatitis, Acute Necrotizing","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000051448","doi":"https://doi.org/10.1159/000051448","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000051448","pdf_url":null,"source":{"id":"https://openalex.org/S28092622","display_name":"Digestion","issn_l":"0012-2823","issn":["0012-2823","1421-9867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestion","raw_type":"journal-article"},{"id":"pmid:10026426","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10026426","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestion","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W289597657","https://openalex.org/W1982646477","https://openalex.org/W1985045980","https://openalex.org/W2033400666","https://openalex.org/W2035786448","https://openalex.org/W2054934999","https://openalex.org/W2061443884","https://openalex.org/W2095349768","https://openalex.org/W2160221316","https://openalex.org/W2313545497","https://openalex.org/W2403772434","https://openalex.org/W2409218844"],"related_works":["https://openalex.org/W2043647527","https://openalex.org/W2007907354","https://openalex.org/W2069096160","https://openalex.org/W2038952540","https://openalex.org/W329061701","https://openalex.org/W2011790172","https://openalex.org/W2086007572","https://openalex.org/W1994678917","https://openalex.org/W2216723602","https://openalex.org/W7100165665"],"abstract_inverted_index":{"Anecdotal":[0],"and":[1,68,87,118],"uncontrolled":[2],"recommendations":[3],"for":[4,124],"programmatic":[5],"surgical":[6,47,51,101,116],"intervention":[7],"in":[8,39,83,89,103],"necrotizing":[9,105],"pancreatitis":[10,106],"are":[11],"gradually":[12],"being":[13,166],"replaced":[14],"by":[15,135],"nonoperative":[16,31],"approaches":[17],"as":[18,77],"prospective":[19],"natural":[20],"history":[21],"information":[22],"becomes":[23],"available.":[24],"In":[25],"patients":[26],"with":[27,154],"sterile":[28,54,74,104],"pancreatic":[29,55,126],"necrosis,":[30],"managements":[32],"has":[33,57],"now":[34],"been":[35,59],"shown":[36,60],"to":[37,46,61],"result":[38,79],"a":[40,78,90,149],"mortality":[41,93],"rate":[42],"equal":[43],"or":[44,63,137,163],"better":[45],"debridement.":[48],"Moreover,":[49],"since":[50],"debridement":[52,82,102,117],"of":[53,73,80,85,92,132,145,170],"necrosis":[56,75,127],"not":[58],"prevent":[62],"ameliorate":[64],"co-existing":[65],"organ":[66],"failure,":[67],"given":[69],"that":[70,100],"secondary":[71],"infection":[72],"occurs":[76],"operative":[81],"25%":[84],"cases":[86],"results":[88],"trebling":[91],"risk,":[94],"it":[95],"is":[96,152],"becoming":[97],"increasingly":[98],"clear":[99],"will":[107],"become":[108],"the":[109,113,121,141,155,171],"exception":[110],"rather":[111],"than":[112],"rule.":[114],"However,":[115],"drainage":[119,146],"remains":[120,147],"preferred":[122],"approach":[123,151],"infected":[125],"despite":[128],"occasional":[129],"anecdotal":[130],"reports":[131],"successful":[133],"management":[134],"transcutaneous":[136],"endoscopic":[138],"means.":[139],"While":[140],"optimal":[142],"post-surgical":[143],"technique":[144],"controversial,":[148],"selective":[150],"reasonable,":[153],"choice":[156],"between":[157],"closed":[158],"drainage,":[159],"lesser":[160],"sac":[161],"lavage,":[162],"schedule":[164],"re-explorations":[165],"based":[167],"upon":[168],"extent":[169],"necrotic":[172],"process.":[173]},"counts_by_year":[{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}