{"id":"https://openalex.org/W1971584062","doi":"https://doi.org/10.1016/j.tet.2009.09.018","title":"Norbornane as the novel pseudoglycone moiety in nucleosides","display_name":"Norbornane as the novel pseudoglycone moiety in nucleosides","publication_year":2009,"publication_date":"2009-09-10","ids":{"openalex":"https://openalex.org/W1971584062","doi":"https://doi.org/10.1016/j.tet.2009.09.018","mag":"1971584062"},"language":"en","primary_location":{"id":"doi:10.1016/j.tet.2009.09.018","doi":"https://doi.org/10.1016/j.tet.2009.09.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tet.2009.09.018","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068675942","display_name":"Michal \u0160\u00e1la","orcid":"https://orcid.org/0000-0003-1554-6906","observed_orcids":["https://orcid.org/0000-0003-1554-6906"]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210145889","display_name":"Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry","ror":"https://ror.org/04nfjn472","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}],"countries":["CZ"],"is_corresponding":true,"raw_author_name":"Michal \u0160\u00e1la","raw_affiliation_strings":["Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008553141","display_name":"Hubert H\u0159ebabeck\u00fd","orcid":"https://orcid.org/0000-0001-7211-390X","observed_orcids":["https://orcid.org/0000-0001-7211-390X"]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210145889","display_name":"Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry","ror":"https://ror.org/04nfjn472","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Hubert H\u0159ebabeck\u00fd","raw_affiliation_strings":["Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028880379","display_name":"Martin Dra\u010d\u00ednsk\u00fd","orcid":"https://orcid.org/0000-0002-4495-0070","observed_orcids":["https://orcid.org/0000-0002-4495-0070"]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210145889","display_name":"Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry","ror":"https://ror.org/04nfjn472","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Martin Dra\u010d\u00ednsk\u00fd","raw_affiliation_strings":["Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000625532","display_name":"Milena Masoj\u0131\u0301dkov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210145889","display_name":"Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry","ror":"https://ror.org/04nfjn472","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Milena Masoj\u00eddkov\u00e1","raw_affiliation_strings":["Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103855024","display_name":"Armando M. De Palma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Armando M. De Palma","raw_affiliation_strings":["Rega Institute for Medical Research, Minderbroedersstraat 10, BE-3000, Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rega Institute for Medical Research, Minderbroedersstraat 10, BE-3000, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089010495","display_name":"Johan H. Neyts","orcid":"https://orcid.org/0000-0002-0033-7514","observed_orcids":["https://orcid.org/0000-0002-0033-7514"]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Johan Neyts","raw_affiliation_strings":["Rega Institute for Medical Research, Minderbroedersstraat 10, BE-3000, Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rega Institute for Medical Research, Minderbroedersstraat 10, BE-3000, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111746439","display_name":"Anton\u0131\u0301n Hol\u00fd","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I202391551","display_name":"Czech Academy of Sciences","ror":"https://ror.org/053avzc18","country_code":"CZ","type":"government","lineage":["https://openalex.org/I202391551"]},{"id":"https://openalex.org/I4210145889","display_name":"Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry","ror":"https://ror.org/04nfjn472","country_code":"CZ","type":"facility","lineage":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Anton\u00edn Hol\u00fd","raw_affiliation_strings":["Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, 166 10 Prague 6, Czech Republic","institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5068675942"],"corresponding_institution_ids":["https://openalex.org/I202391551","https://openalex.org/I4210145889"],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":2.0626,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.8520832,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"65","issue":"45","first_page":"9291","last_page":"9299"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.24410000443458557,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.24410000443458557,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.20229999721050262,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.1648000031709671,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/norbornane","display_name":"norbornane","score":0.949999988079071},{"id":"https://openalex.org/keywords/nucleoside-analogs","display_name":"nucleoside analogues","score":0.9649999737739563},{"id":"https://openalex.org/keywords/bicyclo-2-2-1-heptene","display_name":"bicyclo[2.2.1]heptene","score":0.953000009059906},{"id":"https://openalex.org/keywords/ritter-reaction","display_name":"Ritter reaction","score":0.7699999809265137},{"id":"https://openalex.org/keywords/linear-synthesis","display_name":"linear synthesis","score":0.6660000085830688},{"id":"https://openalex.org/keywords/cytostatic-effect","display_name":"cytostatic activity","score":0.9589999914169312},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":1.0}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9380437731742859},{"id":"https://openalex.org/C2776162329","wikidata":"https://www.wikidata.org/wiki/Q15687131","display_name":"Heptene","level":3,"score":0.863693118095398},{"id":"https://openalex.org/C2780795484","wikidata":"https://www.wikidata.org/wiki/Q418111","display_name":"Norbornane","level":2,"score":0.8432210683822632},{"id":"https://openalex.org/C61234307","wikidata":"https://www.wikidata.org/wiki/Q422960","display_name":"Nucleobase","level":3,"score":0.8158352375030518},{"id":"https://openalex.org/C24961977","wikidata":"https://www.wikidata.org/wiki/Q225972","display_name":"Bicyclic molecule","level":2,"score":0.7878639698028564},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.6774564981460571},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6224713921546936},{"id":"https://openalex.org/C2776543447","wikidata":"https://www.wikidata.org/wiki/Q28734","display_name":"Nucleoside","level":2,"score":0.62019282579422},{"id":"https://openalex.org/C2777854178","wikidata":"https://www.wikidata.org/wiki/Q150668","display_name":"Heptane","level":2,"score":0.4477991461753845},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.33752715587615967},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1869487762451172},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.1138511598110199},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07401418685913086}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.tet.2009.09.018","doi":"https://doi.org/10.1016/j.tet.2009.09.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tet.2009.09.018","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2856002380","display_name":null,"funder_award_id":"1QS400550501","funder_id":"https://openalex.org/F4320322482","funder_display_name":"Akademie V\u011bd \u010cesk\u00e9 Republiky"},{"id":"https://openalex.org/G8080343049","display_name":"New Antivirals and Antineoplastics","funder_award_id":"1M0508","funder_id":"https://openalex.org/F4320321005","funder_display_name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy"}],"funders":[{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"},{"id":"https://openalex.org/F4320321005","display_name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","ror":"https://ror.org/037n8p820"},{"id":"https://openalex.org/F4320322482","display_name":"Akademie V\u011bd \u010cesk\u00e9 Republiky","ror":"https://ror.org/053avzc18"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1966866013","https://openalex.org/W1968249260","https://openalex.org/W1978579339","https://openalex.org/W1993165931","https://openalex.org/W2003917476","https://openalex.org/W2024682383","https://openalex.org/W2025904622","https://openalex.org/W2036775472","https://openalex.org/W2054047850","https://openalex.org/W2086055371","https://openalex.org/W2090780418","https://openalex.org/W2095376060","https://openalex.org/W2145598186","https://openalex.org/W2149702677","https://openalex.org/W2177372459","https://openalex.org/W2325574214","https://openalex.org/W2527460096","https://openalex.org/W2949427308","https://openalex.org/W2949463512","https://openalex.org/W2949595208","https://openalex.org/W2949606492","https://openalex.org/W2950092000","https://openalex.org/W2950934573","https://openalex.org/W2951278933","https://openalex.org/W2951410691","https://openalex.org/W2951877837","https://openalex.org/W2952330013","https://openalex.org/W2952446643","https://openalex.org/W2952585274","https://openalex.org/W2952952288"],"related_works":["https://openalex.org/W2154558565","https://openalex.org/W4307432309","https://openalex.org/W2224231160","https://openalex.org/W2030877949","https://openalex.org/W2166533732","https://openalex.org/W2020973033","https://openalex.org/W1991587885","https://openalex.org/W2004585224","https://openalex.org/W1987089731","https://openalex.org/W1966464528"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}